Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHS70_RS19930 Genome accession   NZ_CP107945
Coordinates   4540640..4541284 (-) Length   214 a.a.
NCBI ID   WP_328399143.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00390     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4535640..4546284
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHS70_RS19905 (OHS70_19925) - 4536724..4537203 (+) 480 WP_328399139.1 GNAT family N-acetyltransferase -
  OHS70_RS19910 (OHS70_19930) - 4537200..4538195 (-) 996 WP_328399140.1 zinc-binding dehydrogenase -
  OHS70_RS19915 (OHS70_19935) - 4538325..4539011 (+) 687 WP_328399141.1 pentapeptide repeat-containing protein -
  OHS70_RS19920 (OHS70_19940) - 4539367..4539867 (-) 501 WP_328399142.1 hypothetical protein -
  OHS70_RS19925 (OHS70_19945) - 4540040..4540630 (+) 591 WP_328405766.1 Uma2 family endonuclease -
  OHS70_RS19930 (OHS70_19950) vraR 4540640..4541284 (-) 645 WP_328399143.1 response regulator transcription factor Regulator
  OHS70_RS19935 (OHS70_19955) - 4541281..4542396 (-) 1116 WP_328405768.1 sensor histidine kinase -
  OHS70_RS19940 (OHS70_19960) - 4542738..4543226 (+) 489 WP_328405770.1 heme-binding protein -
  OHS70_RS19945 (OHS70_19965) - 4543342..4544745 (+) 1404 WP_328399144.1 M1 family metallopeptidase -
  OHS70_RS19950 (OHS70_19970) - 4544767..4545480 (-) 714 WP_328399145.1 hypothetical protein -
  OHS70_RS19955 (OHS70_19975) - 4545578..4546153 (-) 576 WP_328399146.1 TerD family protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 22441.85 Da        Isoelectric Point: 6.4974

>NTDB_id=649869 OHS70_RS19930 WP_328399143.1 4540640..4541284(-) (vraR) [Streptomyces sp. NBC_00390]
MTVGKAALHGTRILLCDDHAVVRAGLLALLGSESDIEVVGEAGSGEEAVAMAAKRKPDVVLMDLQLGAGIDGVEATRRIA
SPEVHVLVLTTYDTDADITRAIEAGATGYLLKAERPEELFAAIRAAAEGRTALSAPVAGRVMDRMRGAAGPTLTNRERDI
LGQLAQGLGNREIARALFISEATVKTHLGRIYAKLGVDTRAGAVAVAKEQRLLL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=649869 OHS70_RS19930 WP_328399143.1 4540640..4541284(-) (vraR) [Streptomyces sp. NBC_00390]
ATGACGGTCGGCAAGGCGGCCCTGCACGGCACACGGATCCTGCTCTGCGACGACCACGCGGTCGTACGCGCCGGACTGCT
CGCCCTCCTTGGCAGCGAGAGCGACATCGAGGTCGTGGGCGAGGCGGGCAGCGGTGAGGAGGCCGTCGCCATGGCCGCCA
AACGGAAGCCGGACGTCGTACTGATGGACCTCCAGCTCGGGGCGGGCATCGACGGGGTCGAGGCCACCCGCCGGATCGCC
TCCCCCGAGGTCCATGTCCTGGTGCTCACCACATACGACACGGACGCCGACATCACCCGCGCCATCGAGGCGGGCGCGAC
GGGCTATCTGCTGAAGGCCGAGCGGCCCGAGGAGCTCTTCGCGGCGATCCGCGCGGCGGCCGAGGGGCGCACCGCACTGT
CGGCCCCGGTCGCCGGCCGCGTCATGGACCGCATGCGGGGCGCGGCCGGCCCGACCCTGACGAACCGCGAACGCGACATC
CTCGGCCAGCTCGCCCAGGGCCTGGGCAACAGGGAGATCGCGCGCGCCCTGTTCATCAGCGAGGCGACGGTGAAGACACA
CCTGGGCCGCATCTACGCCAAGCTGGGCGTGGACACACGGGCGGGGGCGGTGGCGGTGGCGAAGGAGCAGCGGCTGCTGC
TGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(13-124)

Bacterial regulatory proteins, luxR family (GerE)

(152-207)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.262

96.262

0.397
  degU Bacillus subtilis subsp. subtilis str. 168

35.945

100

0.364