Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHS70_RS11390 Genome accession   NZ_CP107945
Coordinates   2757879..2758577 (+) Length   232 a.a.
NCBI ID   WP_328396345.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00390     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2752879..2763577
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHS70_RS11365 (OHS70_11380) - 2753844..2754167 (-) 324 WP_328396335.1 STAS domain-containing protein -
  OHS70_RS11370 (OHS70_11385) - 2754294..2755142 (-) 849 WP_328396337.1 3-hydroxyacyl-CoA dehydrogenase family protein -
  OHS70_RS11375 (OHS70_11390) - 2755363..2755935 (+) 573 WP_328396339.1 cob(I)yrinic acid a,c-diamide adenosyltransferase -
  OHS70_RS11380 (OHS70_11395) - 2755932..2756525 (-) 594 WP_328396341.1 hypothetical protein -
  OHS70_RS11385 (OHS70_11400) - 2756677..2757882 (+) 1206 WP_328396343.1 histidine kinase -
  OHS70_RS11390 (OHS70_11405) vraR 2757879..2758577 (+) 699 WP_328396345.1 response regulator transcription factor Regulator
  OHS70_RS11395 (OHS70_11410) - 2758821..2760587 (+) 1767 WP_328405555.1 glycoside hydrolase family 18 chitinase -
  OHS70_RS11400 (OHS70_11415) - 2760672..2761529 (+) 858 WP_328396347.1 metallophosphoesterase -
  OHS70_RS11405 (OHS70_11420) - 2761728..2762174 (-) 447 WP_328396349.1 DUF2550 domain-containing protein -
  OHS70_RS11410 (OHS70_11425) - 2762302..2762685 (-) 384 WP_328396351.1 F0F1 ATP synthase subunit epsilon -

Sequence

Protein


Download         Length: 232 a.a.        Molecular weight: 24523.18 Da        Isoelectric Point: 4.8752

>NTDB_id=649845 OHS70_RS11390 WP_328396345.1 2757879..2758577(+) (vraR) [Streptomyces sp. NBC_00390]
MTSPAVPPHEPGRDGPHTISVLVAEDQSAVRAGLVLILRSAADIEVVGEAADGEEAVRLARELRPDLVLMDVQMPKLDGV
SATRQVTAERLADVLVLTTFDLDEYVFGALRAGASGFLLKNTEAKDLLDAVRTVARGEGLIAPAVTRRLIAEFASAAPVR
PADAPDPAVLDALTRREREVLSCLGAGLSNAEIAGRLSMAETTVKTHVSRLLGKLELRSRVQAAVLAQELGV

Nucleotide


Download         Length: 699 bp        

>NTDB_id=649845 OHS70_RS11390 WP_328396345.1 2757879..2758577(+) (vraR) [Streptomyces sp. NBC_00390]
ATGACGTCCCCCGCAGTTCCGCCGCACGAGCCCGGCAGGGACGGCCCGCACACCATCAGCGTGCTGGTGGCCGAGGACCA
GAGCGCCGTGCGCGCGGGTCTGGTCCTGATCCTGCGCAGCGCTGCGGACATCGAGGTGGTCGGCGAAGCCGCGGACGGCG
AGGAGGCGGTACGGCTGGCCCGTGAGCTGCGCCCCGATCTGGTGCTGATGGATGTGCAGATGCCGAAGCTGGACGGGGTC
TCGGCGACCCGGCAGGTGACGGCCGAGCGGCTGGCGGACGTGCTCGTACTGACGACGTTCGATCTCGACGAGTACGTCTT
CGGGGCGCTGCGGGCCGGGGCCTCCGGCTTTCTGCTGAAGAACACCGAAGCGAAGGATCTGCTCGATGCGGTGCGCACGG
TGGCGCGCGGCGAAGGGCTGATCGCGCCCGCCGTGACGCGCAGGCTGATCGCGGAGTTCGCCTCGGCCGCACCGGTACGG
CCGGCGGACGCGCCGGACCCGGCCGTTCTCGATGCGCTGACGCGACGGGAGCGCGAGGTGCTCTCGTGTCTCGGCGCGGG
GCTGTCGAACGCCGAGATCGCCGGCCGGCTGTCGATGGCGGAGACCACGGTGAAGACGCACGTCAGCCGTCTGCTGGGGA
AGCTGGAGCTGCGCAGCCGGGTCCAAGCAGCCGTGCTGGCCCAGGAGTTGGGGGTCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(21-132)

Bacterial regulatory proteins, luxR family (GerE)

(172-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

42.654

90.948

0.388
  degU Bacillus subtilis subsp. subtilis str. 168

38.914

95.259

0.371