Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHS70_RS09295 Genome accession   NZ_CP107945
Coordinates   2272229..2272903 (-) Length   224 a.a.
NCBI ID   WP_328395594.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00390     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2267229..2277903
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHS70_RS09270 (OHS70_09285) - 2267389..2267970 (+) 582 WP_328405511.1 hypothetical protein -
  OHS70_RS09275 (OHS70_09290) - 2268123..2269853 (+) 1731 WP_328395588.1 sensor histidine kinase -
  OHS70_RS09280 (OHS70_09295) - 2269850..2269957 (+) 108 Protein_1851 two-component system response regulator -
  OHS70_RS09285 (OHS70_09300) - 2270029..2271651 (-) 1623 WP_328395590.1 cation acetate symporter -
  OHS70_RS09290 (OHS70_09305) - 2271648..2272130 (-) 483 WP_328395592.1 DUF485 domain-containing protein -
  OHS70_RS09295 (OHS70_09310) vraR 2272229..2272903 (-) 675 WP_328395594.1 response regulator transcription factor Regulator
  OHS70_RS09300 (OHS70_09315) - 2272900..2274060 (-) 1161 WP_328395596.1 sensor histidine kinase -
  OHS70_RS09305 (OHS70_09320) - 2274164..2276290 (-) 2127 WP_328395598.1 DNA topoisomerase IV subunit B -
  OHS70_RS09310 (OHS70_09325) - 2276725..2276955 (+) 231 WP_328395600.1 hypothetical protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 24119.55 Da        Isoelectric Point: 5.3766

>NTDB_id=649835 OHS70_RS09295 WP_328395594.1 2272229..2272903(-) (vraR) [Streptomyces sp. NBC_00390]
MTGQIARVIVADDQAVVREGIVMLLGLLPGIQVVGSARDGEEAFALVAELDPDVVLMDLRMPRCDGVEATRRIRREHPAT
QVVVLTTYADDDSLFPALRAGARGYLTKDADGDEISRAIRDVVAGRAGLSPVVQQRLLEQVTAPTEPAAPRLPDGLTARE
GEVLTLIAEGLSNADIARSLQISTATVKTHINNLFAKAGLHDRAQAVRYAYREGLAQPPRNRIT

Nucleotide


Download         Length: 675 bp        

>NTDB_id=649835 OHS70_RS09295 WP_328395594.1 2272229..2272903(-) (vraR) [Streptomyces sp. NBC_00390]
ATGACCGGGCAGATCGCCCGAGTGATCGTCGCCGATGATCAGGCGGTGGTGCGCGAGGGCATCGTGATGCTGCTGGGGCT
GCTGCCCGGTATCCAGGTCGTGGGCTCGGCCAGGGACGGTGAGGAAGCGTTCGCCCTGGTCGCCGAACTCGATCCCGATG
TCGTCCTGATGGACCTGCGGATGCCCCGCTGCGACGGGGTCGAGGCCACCCGCCGTATCCGCCGTGAGCATCCTGCGACC
CAGGTGGTGGTGCTCACCACGTACGCGGACGACGACTCCCTCTTCCCGGCGCTGCGTGCGGGCGCACGCGGCTATCTCAC
CAAGGACGCCGACGGCGACGAGATCTCGCGGGCCATCCGCGATGTCGTCGCCGGACGGGCCGGGCTTTCCCCGGTGGTGC
AGCAAAGACTGCTCGAGCAGGTCACGGCACCGACCGAGCCGGCCGCGCCGCGGCTGCCCGACGGCCTGACCGCCCGTGAG
GGCGAGGTGCTCACCCTGATCGCGGAGGGCCTCAGCAACGCCGACATCGCCCGCAGTCTGCAGATCTCGACCGCCACCGT
GAAGACCCACATCAACAACCTGTTCGCCAAGGCCGGACTCCACGACAGGGCCCAGGCAGTGCGCTACGCCTACCGCGAGG
GCCTCGCGCAGCCGCCCCGGAACCGCATCACCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(155-210)

Response regulator receiver domain (Response_reg)

(8-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.863

94.196

0.366
  degU Bacillus subtilis subsp. subtilis str. 168

36.771

99.554

0.366