Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHS70_RS06370 Genome accession   NZ_CP107945
Coordinates   1468711..1469385 (-) Length   224 a.a.
NCBI ID   WP_328394538.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00390     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1463711..1474385
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHS70_RS06350 (OHS70_06360) - 1464234..1464854 (-) 621 WP_328394534.1 dihydrofolate reductase family protein -
  OHS70_RS06355 (OHS70_06365) alc 1465041..1466156 (-) 1116 WP_328405453.1 allantoicase -
  OHS70_RS06360 (OHS70_06370) allB 1466156..1467496 (-) 1341 WP_328405456.1 allantoinase AllB -
  OHS70_RS06365 (OHS70_06375) - 1467889..1468683 (+) 795 WP_328394536.1 IclR family transcriptional regulator -
  OHS70_RS06370 (OHS70_06380) vraR 1468711..1469385 (-) 675 WP_328394538.1 response regulator transcription factor Regulator
  OHS70_RS06375 (OHS70_06385) - 1469427..1470725 (-) 1299 WP_328394540.1 sensor histidine kinase -
  OHS70_RS06380 (OHS70_06390) - 1470727..1471896 (-) 1170 WP_328394541.1 acyltransferase -
  OHS70_RS06385 (OHS70_06395) - 1471889..1472845 (-) 957 WP_328394543.1 alpha/beta hydrolase -
  OHS70_RS06390 (OHS70_06400) - 1473149..1473472 (-) 324 WP_328394545.1 DUF5955 family protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 24053.83 Da        Isoelectric Point: 4.8357

>NTDB_id=649831 OHS70_RS06370 WP_328394538.1 1468711..1469385(-) (vraR) [Streptomyces sp. NBC_00390]
MTIPIRVLIADDQMMVRQGFTVLLDAEPGIEVVGQAVNGLEAIAKVAELDPDVVLMDIRMPELGGIEATRRITEQDGATV
QVLVLTTFDLDEYVYEALRAGASGFLLKDASAGELAQAVRVVAAGDALLAPNVTKRLIAEFSRMTRSPRAPLKDRVGGLT
ERETEVLSLIAQGLSNAEIAGRLVVAEQTVKTHVSRILVKLGLRDRTQAAVFAYETGLVRPAGH

Nucleotide


Download         Length: 675 bp        

>NTDB_id=649831 OHS70_RS06370 WP_328394538.1 1468711..1469385(-) (vraR) [Streptomyces sp. NBC_00390]
ATGACGATCCCCATCCGTGTACTGATCGCCGACGACCAGATGATGGTCCGTCAGGGCTTCACGGTGCTGCTCGACGCCGA
ACCCGGCATCGAGGTCGTCGGCCAGGCGGTGAACGGTCTCGAGGCGATCGCCAAGGTCGCCGAACTCGACCCGGACGTGG
TCCTGATGGACATCCGGATGCCCGAACTCGGCGGCATAGAGGCGACCCGCCGCATCACCGAACAGGACGGCGCCACCGTC
CAGGTCCTCGTACTGACCACCTTCGACCTCGACGAGTACGTGTACGAGGCGCTGCGCGCGGGCGCGTCCGGGTTCCTGCT
GAAGGACGCCTCCGCCGGCGAACTCGCCCAGGCGGTGCGGGTGGTGGCGGCCGGCGACGCGCTGCTCGCCCCGAACGTCA
CCAAGCGGCTCATCGCCGAGTTCTCCCGGATGACGCGCTCCCCGCGGGCGCCGCTCAAGGATCGCGTCGGCGGTCTGACG
GAACGCGAGACGGAGGTCCTGTCCCTCATCGCGCAGGGCCTGTCGAACGCGGAGATCGCCGGGCGTCTGGTCGTGGCGGA
GCAGACCGTGAAGACCCATGTGAGCCGCATCCTGGTCAAGCTGGGTCTGCGTGACCGGACCCAGGCCGCGGTCTTCGCGT
ACGAGACGGGCCTGGTGCGCCCAGCAGGTCACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-120)

Bacterial regulatory proteins, luxR family (GerE)

(159-213)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.954

97.321

0.437
  degU Bacillus subtilis subsp. subtilis str. 168

41.518

100

0.415