Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG212_RS44630 Genome accession   NZ_CP107944
Coordinates   10245373..10246011 (+) Length   212 a.a.
NCBI ID   WP_326585966.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00391     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 10240373..10251011
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG212_RS44610 - 10241003..10241182 (+) 180 Protein_8828 hypothetical protein -
  OG212_RS44615 (OG212_44695) - 10241100..10241696 (+) 597 WP_328507976.1 FCD domain-containing protein -
  OG212_RS44620 (OG212_44700) - 10241711..10243351 (-) 1641 WP_328507977.1 AMP-binding protein -
  OG212_RS44625 (OG212_44705) - 10243721..10245376 (+) 1656 WP_328507978.1 GAF domain-containing sensor histidine kinase -
  OG212_RS44630 (OG212_44710) vraR 10245373..10246011 (+) 639 WP_326585966.1 response regulator transcription factor Regulator
  OG212_RS44635 (OG212_44715) - 10246155..10247066 (+) 912 WP_328507979.1 SDR family oxidoreductase -
  OG212_RS44640 - 10247121..10247354 (-) 234 WP_326585140.1 IclR family transcriptional regulator C-terminal domain-containing protein -
  OG212_RS44645 - 10247394..10247633 (-) 240 WP_328507980.1 IclR family transcriptional regulator C-terminal domain-containing protein -
  OG212_RS44650 (OG212_44725) - 10247781..10248239 (+) 459 WP_328507981.1 aldehyde dehydrogenase family protein -
  OG212_RS44655 (OG212_44730) - 10248130..10248357 (+) 228 WP_328508258.1 aldehyde dehydrogenase family protein -
  OG212_RS44660 (OG212_44735) - 10248327..10249271 (-) 945 WP_328507982.1 superoxide dismutase -

Sequence

Protein


Download         Length: 212 a.a.        Molecular weight: 22701.25 Da        Isoelectric Point: 6.3476

>NTDB_id=649828 OG212_RS44630 WP_326585966.1 10245373..10246011(+) (vraR) [Streptomyces sp. NBC_00391]
MIVDDHAVVRRGIRAYLEVLDDMEVAAEAADGQEALTRLDAMAAHRELPDVVLIDLLMPKMDGVTAIGAIKQRHPGLRLV
VLTSFGEMERVHAALAQGAAGYLLKDAEAGEVVAAIRAAARGEVFLDPAVARGLTQEIVSPPTGLASLTSRERDVLVLVA
EGRSNQQIADELVISERTARTHVSNVLRKLRLTSRTQAALLAVRQGLVPPKG

Nucleotide


Download         Length: 639 bp        

>NTDB_id=649828 OG212_RS44630 WP_326585966.1 10245373..10246011(+) (vraR) [Streptomyces sp. NBC_00391]
CTGATCGTCGACGACCACGCCGTCGTACGCCGCGGAATCCGTGCCTACCTCGAGGTCCTGGACGACATGGAAGTGGCCGC
GGAGGCCGCCGACGGCCAGGAGGCACTCACCCGGCTCGACGCGATGGCCGCCCACCGGGAACTGCCGGACGTGGTCTTGA
TTGACCTGCTCATGCCCAAAATGGACGGGGTGACCGCGATCGGAGCGATCAAGCAGCGCCACCCCGGTCTCCGACTCGTG
GTGCTCACCAGCTTCGGAGAGATGGAACGCGTCCACGCGGCACTCGCCCAGGGAGCCGCCGGCTACCTACTCAAGGACGC
CGAAGCGGGCGAAGTGGTCGCCGCGATCCGCGCGGCCGCCCGGGGCGAGGTCTTCCTCGACCCCGCGGTGGCCAGGGGAC
TCACCCAGGAGATCGTTTCGCCGCCGACCGGGCTCGCCTCTCTCACCAGCCGGGAACGCGACGTCCTCGTCCTCGTCGCC
GAGGGACGGTCGAACCAGCAGATCGCCGACGAGTTGGTGATCAGCGAGCGCACCGCCCGCACCCACGTGAGCAACGTCCT
GCGCAAACTCCGGCTCACCTCCCGGACCCAGGCCGCATTGCTCGCGGTGCGGCAAGGACTGGTGCCTCCGAAGGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(1-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.385

98.113

0.396
  degU Bacillus subtilis subsp. subtilis str. 168

35.111

100

0.373