Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG212_RS36760 Genome accession   NZ_CP107944
Coordinates   8475164..8475805 (+) Length   213 a.a.
NCBI ID   WP_326583789.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00391     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8470164..8480805
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG212_RS36740 (OG212_36795) - 8471024..8471692 (-) 669 WP_326583785.1 transglycosylase SLT domain-containing protein -
  OG212_RS36745 (OG212_36800) - 8471990..8473090 (-) 1101 WP_328507533.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OG212_RS36750 (OG212_36805) - 8473087..8473782 (-) 696 WP_326583787.1 SDR family NAD(P)-dependent oxidoreductase -
  OG212_RS36755 (OG212_36810) - 8474026..8475171 (+) 1146 WP_326583788.1 GAF domain-containing sensor histidine kinase -
  OG212_RS36760 (OG212_36815) vraR 8475164..8475805 (+) 642 WP_326583789.1 response regulator transcription factor Regulator
  OG212_RS36765 (OG212_36820) chpE 8475963..8476211 (+) 249 WP_033529228.1 chaplin ChpE -
  OG212_RS36770 (OG212_36825) - 8476591..8477376 (-) 786 WP_326583790.1 hypothetical protein -
  OG212_RS36775 (OG212_36830) - 8477527..8478318 (+) 792 WP_326583791.1 ABC transporter ATP-binding protein -
  OG212_RS36780 (OG212_36835) - 8478464..8478895 (+) 432 WP_326583792.1 NfeD family protein -
  OG212_RS36785 (OG212_36840) - 8479055..8480002 (+) 948 WP_326583793.1 SPFH domain-containing protein -
  OG212_RS36790 (OG212_36845) - 8480130..8480636 (-) 507 WP_326583794.1 HNH endonuclease -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 22915.15 Da        Isoelectric Point: 4.9871

>NTDB_id=649820 OG212_RS36760 WP_326583789.1 8475164..8475805(+) (vraR) [Streptomyces sp. NBC_00391]
MADAIKVLLVDDHQVVRRGLRTFLEVQDDIEVVGEAADGAEGVARAEELRPDVVLMDVKMPGMDGVDALRKLRELDNPAR
VLIVTSFTEQRTVVPALRAGAAGYVYKDVDPDALAGAIRSVHAGHILLQPEVADALLSQEQANSGQGRGGSLTEREREVL
GLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRNGVAG

Nucleotide


Download         Length: 642 bp        

>NTDB_id=649820 OG212_RS36760 WP_326583789.1 8475164..8475805(+) (vraR) [Streptomyces sp. NBC_00391]
GTGGCTGACGCAATCAAGGTGCTCCTGGTCGACGACCACCAGGTGGTCCGGCGCGGCCTGCGCACCTTCCTGGAGGTGCA
GGACGACATCGAGGTCGTGGGGGAGGCCGCCGACGGCGCCGAAGGGGTCGCCCGCGCCGAGGAGCTCCGGCCCGACGTCG
TCCTCATGGACGTCAAGATGCCGGGCATGGACGGCGTCGACGCGCTGCGCAAGCTCCGCGAACTCGACAACCCCGCGCGT
GTGCTCATCGTCACCAGCTTCACCGAGCAGCGCACGGTCGTCCCGGCCCTGCGCGCCGGCGCCGCCGGATACGTCTACAA
GGACGTGGACCCCGACGCCCTGGCCGGCGCCATCCGCTCGGTGCACGCCGGGCACATCCTCCTCCAGCCGGAGGTCGCCG
ACGCGCTCCTGTCCCAGGAGCAGGCCAACTCCGGCCAGGGGAGAGGAGGTTCACTCACCGAGCGGGAGCGCGAGGTGCTC
GGTCTGATAGCCGACGGCCGCTCCAACCGCGAGATCGCCCGCGCGCTGGTCCTCTCCGAGAAGACGGTGAAGACCCACGT
CTCGAACATCCTGATGAAGCTCGACCTGGCGGACCGTACACAGGCCGCGCTGTGGGCGGTACGCAACGGTGTGGCCGGAT
GA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(151-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

46.226

99.531

0.46
  degU Bacillus subtilis subsp. subtilis str. 168

38.914

100

0.404