Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHS81_RS25735 Genome accession   NZ_CP107940
Coordinates   5882736..5883416 (-) Length   226 a.a.
NCBI ID   WP_328387019.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00400     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5877736..5888416
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHS81_RS25715 (OHS81_25735) - 5878394..5878879 (+) 486 WP_328387015.1 MerR family transcriptional regulator -
  OHS81_RS25720 (OHS81_25740) - 5878887..5879915 (+) 1029 WP_328387016.1 aldo/keto reductase -
  OHS81_RS25725 (OHS81_25745) - 5879980..5881218 (-) 1239 WP_328387017.1 acyltransferase family protein -
  OHS81_RS25730 (OHS81_25750) - 5881370..5882536 (-) 1167 WP_328387018.1 alpha/beta hydrolase -
  OHS81_RS25735 (OHS81_25755) vraR 5882736..5883416 (-) 681 WP_328387019.1 response regulator transcription factor Regulator
  OHS81_RS25740 (OHS81_25760) - 5883413..5884789 (-) 1377 WP_328387020.1 sensor histidine kinase -
  OHS81_RS25745 (OHS81_25765) - 5884973..5885851 (-) 879 WP_328387021.1 DUF4429 domain-containing protein -
  OHS81_RS25750 (OHS81_25770) - 5886060..5887274 (-) 1215 WP_328387022.1 alpha/beta hydrolase -
  OHS81_RS25755 (OHS81_25775) - 5887527..5888180 (-) 654 WP_328387023.1 TetR/AcrR family transcriptional regulator -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24260.04 Da        Isoelectric Point: 5.7711

>NTDB_id=649741 OHS81_RS25735 WP_328387019.1 5882736..5883416(-) (vraR) [Streptomyces sp. NBC_00400]
MTTRVIIVDDQAMVRAGFAALLAAQSDIEVVGDAPDGVQGVELSRRTHPDVVLMDVRMPEMDGLEAARQLLDPSPGVPHR
PKVLMLTTFDVDDYVYEALRAGASGFLLKDAPPGDLISAVRVVAAGEALLAPSVTRRLIADFARRRPAPRKGRAALQLTG
LTPRETEVLELIARGLSNQEIAAALIVAEQTVKTHVSRVLAKLALRDRAQAVIFAYESGLVTPGEQ

Nucleotide


Download         Length: 681 bp        

>NTDB_id=649741 OHS81_RS25735 WP_328387019.1 5882736..5883416(-) (vraR) [Streptomyces sp. NBC_00400]
ATGACCACGCGCGTGATCATCGTCGACGACCAGGCCATGGTGCGCGCGGGCTTCGCCGCGCTGCTCGCCGCGCAGAGCGA
TATCGAAGTGGTGGGCGATGCGCCGGACGGGGTGCAGGGAGTGGAGCTGAGCCGCCGGACGCACCCCGATGTGGTGCTGA
TGGATGTCCGGATGCCCGAGATGGACGGGCTGGAGGCGGCCCGGCAGCTGCTCGATCCGTCCCCCGGGGTGCCGCACCGC
CCGAAGGTGCTGATGCTGACCACCTTCGATGTCGACGACTACGTCTACGAGGCACTGCGGGCGGGGGCGTCCGGCTTCCT
GCTCAAGGACGCGCCGCCGGGTGATCTGATCTCCGCGGTCCGGGTCGTGGCGGCCGGGGAGGCGCTGCTCGCCCCGTCCG
TGACCCGGCGGCTGATAGCCGATTTCGCCCGCCGGCGGCCCGCGCCCCGCAAGGGCCGGGCGGCGCTACAGCTGACGGGC
CTCACCCCGCGCGAGACGGAGGTGCTGGAGCTGATCGCCCGCGGTCTGTCGAACCAGGAGATCGCCGCTGCGCTGATCGT
CGCCGAGCAGACCGTGAAGACCCATGTCAGCCGGGTGCTCGCCAAGTTGGCGCTGCGGGACCGCGCCCAGGCCGTGATCT
TCGCGTACGAGTCGGGGCTGGTCACGCCCGGGGAGCAGTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(161-215)

Response regulator receiver domain (Response_reg)

(5-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.344

97.788

0.434
  degU Bacillus subtilis subsp. subtilis str. 168

39.474

100

0.398