Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHS59_RS34235 Genome accession   NZ_CP107935
Coordinates   7873170..7873811 (+) Length   213 a.a.
NCBI ID   WP_328497218.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00414     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7868170..7878811
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHS59_RS34215 (OHS59_34225) - 7869022..7869729 (-) 708 WP_328497214.1 transglycosylase SLT domain-containing protein -
  OHS59_RS34220 (OHS59_34230) - 7870030..7871154 (-) 1125 WP_328497215.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OHS59_RS34225 (OHS59_34235) - 7871151..7871846 (-) 696 WP_328497216.1 SDR family NAD(P)-dependent oxidoreductase -
  OHS59_RS34230 (OHS59_34240) - 7872032..7873177 (+) 1146 WP_328497217.1 GAF domain-containing sensor histidine kinase -
  OHS59_RS34235 (OHS59_34245) vraR 7873170..7873811 (+) 642 WP_328497218.1 response regulator transcription factor Regulator
  OHS59_RS34240 (OHS59_34250) chpE 7873995..7874240 (+) 246 WP_328497219.1 chaplin ChpE -
  OHS59_RS34245 (OHS59_34255) - 7874435..7874674 (+) 240 WP_107017791.1 chaplin -
  OHS59_RS34250 (OHS59_34260) - 7874772..7875560 (-) 789 WP_328497220.1 hypothetical protein -
  OHS59_RS34255 (OHS59_34265) - 7875695..7876486 (+) 792 WP_328497221.1 ABC transporter ATP-binding protein -
  OHS59_RS34260 (OHS59_34270) - 7876598..7877029 (+) 432 WP_328497222.1 NfeD family protein -
  OHS59_RS34265 (OHS59_34275) - 7877198..7878160 (+) 963 WP_328497223.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23159.48 Da        Isoelectric Point: 5.1544

>NTDB_id=649668 OHS59_RS34235 WP_328497218.1 7873170..7873811(+) (vraR) [Streptomyces sp. NBC_00414]
MPDAIKVLLVDDHQVVRRGLRTFLEVQDDIEVVGEASDGAEGVARAEELKPDVVLMDVKMPVMDGVEALRRLRELDNPAR
VLIVTSFTEQRTVIPALRAGAAGYVYKDVDPDALAGAIRSVHAGHILLQPEVADVLLSQEGTNYGQGRGGSLTEREREVL
GLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLSDRTQAALWAVRHGVTG

Nucleotide


Download         Length: 642 bp        

>NTDB_id=649668 OHS59_RS34235 WP_328497218.1 7873170..7873811(+) (vraR) [Streptomyces sp. NBC_00414]
GTGCCTGACGCCATCAAGGTGCTGCTCGTCGACGACCACCAGGTGGTCCGCCGGGGGCTGCGCACCTTCCTCGAAGTGCA
GGACGACATCGAGGTCGTGGGGGAGGCGTCCGACGGCGCCGAAGGAGTCGCCCGCGCCGAGGAGTTGAAGCCCGACGTCG
TCCTCATGGACGTCAAGATGCCGGTCATGGACGGCGTGGAGGCCCTGCGCAGGCTCCGCGAACTCGACAACCCCGCGCGC
GTGCTCATCGTCACCAGCTTCACCGAGCAGCGCACGGTGATCCCGGCCCTGCGCGCGGGCGCCGCGGGCTATGTCTACAA
GGACGTCGACCCGGACGCCCTGGCCGGAGCCATCCGCTCGGTCCACGCCGGGCACATCCTGCTCCAGCCCGAGGTGGCCG
ACGTGCTGCTGTCCCAGGAGGGGACCAACTACGGCCAGGGGAGAGGCGGTTCGCTCACCGAGCGGGAGCGCGAGGTACTC
GGCCTGATCGCCGACGGCCGCTCCAACCGCGAGATAGCCCGCGCCCTCGTCCTCTCCGAGAAGACCGTCAAGACGCATGT
ATCGAACATTCTGATGAAACTCGACCTCTCCGACCGCACCCAGGCCGCGCTGTGGGCCGTACGCCACGGTGTGACCGGCT
GA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(151-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

46.445

99.061

0.46
  degU Bacillus subtilis subsp. subtilis str. 168

39.367

100

0.408