Detailed information NTG0649650

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OHS59_RS25295
• Genome accession: NZ_CP107935
• Coordinates: 5819229..5820353 (-)
• Length: 374 a.a.
• NCBI ID: WP_107022362.1
• Uniprot ID: A0A2P8PTM3
• Organism: Streptomyces sp. NBC_00414
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 5814229..5825353

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OHS59_RS25270 (OHS59_25280)	cseB	5814613..5815344 (-)	732	WP_328495679.1	two-component system response regulator CseB	-
OHS59_RS25275 (OHS59_25285)	-	5815413..5816018 (-)	606	WP_328495680.1	hypothetical protein	-
OHS59_RS25280 (OHS59_25290)	-	5816057..5816614 (-)	558	WP_328495681.1	SigE family RNA polymerase sigma factor	-
OHS59_RS25285 (OHS59_25295)	-	5816872..5817801 (-)	930	WP_328495682.1	A/G-specific adenine glycosylase	-
OHS59_RS25290 (OHS59_25300)	-	5818050..5818886 (+)	837	WP_328495683.1	hypothetical protein	-
OHS59_RS25295 (OHS59_25305)	disA	5819229..5820353 (-)	1125	WP_107022362.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OHS59_RS25300 (OHS59_25310)	radA/sms	5820424..5821833 (-)	1410	WP_107022363.1	DNA repair protein RadA	Machinery gene
OHS59_RS25305 (OHS59_25315)	-	5822067..5823986 (+)	1920	WP_328495684.1	hypothetical protein	-
OHS59_RS25310 (OHS59_25320)	-	5824090..5825004 (-)	915	WP_328495685.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40286.15 Da
• Isoelectric Point: 5.0058

>NTDB_id=649650 OHS59_RS25295 WP_107022362.1 5819229..5820353(-) (disA) [Streptomyces sp. NBC_00414]
MAANDRAAVPGKSGGSSGTDGLMRTALSAVAPGTGLRDGLERILRGNTGGLIVLGWDKTVEAMCSGGFVLDVEFTATRLR
ELCKLDGGIVLDKDITKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALFELNALSHAELLEMPTVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=649650 OHS59_RS25295 WP_107022362.1 5819229..5820353(-) (disA) [Streptomyces sp. NBC_00414]
GTGGCAGCCAACGACCGGGCAGCAGTTCCCGGCAAGTCCGGCGGGAGTTCCGGCACCGATGGCCTGATGCGCACGGCTCT
CAGCGCTGTGGCACCCGGCACCGGGCTGCGTGACGGCCTGGAGCGAATCCTCCGCGGCAACACCGGCGGGCTCATCGTGC
TCGGCTGGGACAAGACCGTCGAGGCGATGTGCAGCGGCGGTTTCGTGCTGGACGTGGAGTTCACCGCGACCCGGCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTGCTGGACAAGGACATCACCAAGATCCTGCGGGCCGGCGTGCAGCTGGTCCC
CGACCCGACCATCCCCACCGAGGAGACGGGCACGCGGCACCGCACGGCGGACCGGGTGAGCAAGCAGGTCGGCTTCCCCG
TCGTCTCCGTCTCCCAGTCCATGCGCCTGATCGCGCTGTACGTGGACGGGCAGCGGCGGGTCCTGGAGGACTCGGCCGCG
ATCCTCTCCCGTGCCAACCAGGCGCTGGCCACGCTGGAGCGGTACAAGCTGCGGCTCGACGAGGTCGCGGGCACGTTGTC
CGCGCTGGAGATCGAGGACCTGGTCACCGTCCGGGACGTGTCGGCGGTGGCCCAGCGGCTGGAGATGGTGCGCCGGATCG
CCACGGAGATCGCCGAGTACGTGGTGGAGCTGGGCACGGACGGGCGGCTGCTCTCGCTGCAGCTGGACGAGCTGATCGCC
GGGGTCGAGCCCGAGCGGGAGCTCGTCGTACGGGACTATGTGCCCGAGCCGACGGCCAAGCGGTCCCGCACGGTGGACGA
GGCGCTGTTCGAGCTGAACGCGCTCAGTCATGCGGAGCTGCTCGAAATGCCCACCGTGGCGCGGGCGTTGGGGTACACGG
GGTCGCCCGAGGCGCTCGACTCCGCGGTGTCGCCCCGCGGGTTCCGGTTGCTGGCCAAGGTGCCGCGGCTGCCCGGCGCG
ATCATCGACCGGCTGGTCGAGCACTTCGGCGGGCTGCAGAAGCTGCTCGCCGCGAGCGTGGATGATCTGCAGACCGTGGA
CGGGGTGGGGGAGGCTCGGGCCCGAAGCGTGCGGGAGGGGCTTTCCCGGCTGGCGGAGTCGTCGATTCTCGAACGCTACG
TGTAG

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• Helix-hairpin-helix motif (HHH_2) (324-359)

3D structure

• AlphaFold DB: A0A2P8PTM3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.429	96.524	0.438