Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHS59_RS12835 Genome accession   NZ_CP107935
Coordinates   2998476..2999156 (-) Length   226 a.a.
NCBI ID   WP_328493544.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00414     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2993476..3004156
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHS59_RS12815 (OHS59_12830) - 2993889..2995574 (+) 1686 WP_328493540.1 sensor histidine kinase -
  OHS59_RS12820 (OHS59_12835) - 2995571..2996251 (+) 681 WP_328493541.1 response regulator -
  OHS59_RS12825 (OHS59_12840) - 2996294..2997886 (-) 1593 WP_328493542.1 cation acetate symporter -
  OHS59_RS12830 (OHS59_12845) - 2997883..2998371 (-) 489 WP_328493543.1 DUF485 domain-containing protein -
  OHS59_RS12835 (OHS59_12850) vraR 2998476..2999156 (-) 681 WP_328493544.1 response regulator transcription factor Regulator
  OHS59_RS12840 (OHS59_12855) - 2999153..3000304 (-) 1152 WP_328493545.1 histidine kinase -
  OHS59_RS12845 (OHS59_12860) - 3000301..3000825 (-) 525 WP_328493546.1 DUF1453 domain-containing protein -
  OHS59_RS12850 (OHS59_12865) - 3001177..3003300 (-) 2124 WP_328493547.1 DNA topoisomerase IV subunit B -
  OHS59_RS12855 (OHS59_12870) - 3003741..3003971 (+) 231 WP_107021495.1 hypothetical protein -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24206.75 Da        Isoelectric Point: 5.4120

>NTDB_id=649614 OHS59_RS12835 WP_328493544.1 2998476..2999156(-) (vraR) [Streptomyces sp. NBC_00414]
MTAESGAQPARVVVADDQTVVREGIVMLLGLLPGIEVVGAAADGNEAVRLVAELDPDVVLMDLRMPRCDGVEATRRIRSE
HPRTQVVVLTTFADDESLFPALRAGARGYLTKDADGNEIVRAVRSVLSGDAGFSPGIQRRLLERLSEPQAVVPAQEAPDG
LTLRETEVLVLIADGLTNQEIARKLQVSTATVKIHINNLFAKTGLRDRAQAVRYAFGKGLVRPPGG

Nucleotide


Download         Length: 681 bp        

>NTDB_id=649614 OHS59_RS12835 WP_328493544.1 2998476..2999156(-) (vraR) [Streptomyces sp. NBC_00414]
ATGACGGCGGAGTCCGGTGCGCAGCCTGCTCGTGTCGTGGTGGCGGACGACCAGACCGTGGTGCGCGAGGGCATCGTGAT
GCTGCTCGGCCTGCTGCCGGGGATCGAGGTCGTCGGTGCGGCCGCCGACGGAAACGAGGCGGTACGGCTGGTGGCCGAGC
TCGACCCGGACGTGGTGCTGATGGATTTGCGCATGCCTCGCTGCGACGGAGTCGAGGCGACCAGGCGCATCAGGTCCGAG
CATCCGAGGACGCAGGTCGTCGTGCTCACCACGTTCGCCGACGACGAGTCGCTGTTTCCCGCTCTGCGAGCGGGCGCTCG
CGGCTATCTCACCAAGGACGCGGACGGGAACGAGATCGTCCGAGCCGTGCGGAGTGTGCTGTCCGGGGACGCGGGGTTCT
CGCCGGGCATCCAGCGACGTTTGCTGGAGCGACTGTCGGAACCGCAGGCTGTCGTGCCCGCTCAGGAGGCTCCGGACGGG
CTCACCCTGCGGGAGACGGAGGTGCTGGTGCTGATCGCCGACGGCCTGACCAACCAGGAGATCGCCCGCAAGCTGCAGGT
GTCCACGGCCACGGTGAAGATCCACATCAACAACCTCTTCGCAAAGACGGGACTCAGGGACCGTGCGCAGGCCGTCCGTT
ACGCCTTCGGGAAGGGACTTGTGCGGCCACCAGGGGGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(160-215)

Response regulator receiver domain (Response_reg)

(12-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.623

93.805

0.372
  degU Bacillus subtilis subsp. subtilis str. 168

37.557

97.788

0.367