Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHS59_RS05230 Genome accession   NZ_CP107935
Coordinates   1191767..1192432 (+) Length   221 a.a.
NCBI ID   WP_328492213.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00414     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1186767..1197432
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHS59_RS05205 (OHS59_05205) - 1187002..1188054 (-) 1053 WP_328492208.1 low specificity L-threonine aldolase -
  OHS59_RS05210 (OHS59_05210) - 1188121..1188786 (-) 666 WP_328492209.1 TetR/AcrR family transcriptional regulator C-terminal domain-containing protein -
  OHS59_RS05215 (OHS59_05215) - 1188944..1189867 (+) 924 WP_328492210.1 ATP-binding cassette domain-containing protein -
  OHS59_RS05220 (OHS59_05220) - 1189876..1190583 (+) 708 WP_328492211.1 ABC transporter permease -
  OHS59_RS05225 (OHS59_05225) - 1190580..1191770 (+) 1191 WP_328492212.1 histidine kinase -
  OHS59_RS05230 (OHS59_05230) vraR 1191767..1192432 (+) 666 WP_328492213.1 response regulator transcription factor Regulator
  OHS59_RS05235 (OHS59_05235) - 1192634..1193752 (+) 1119 WP_328492214.1 hypothetical protein -
  OHS59_RS05240 (OHS59_05240) - 1193851..1194303 (-) 453 WP_328492215.1 hypothetical protein -
  OHS59_RS05245 (OHS59_05245) - 1194337..1194792 (-) 456 WP_328492216.1 SHOCT domain-containing protein -
  OHS59_RS05250 (OHS59_05250) - 1194870..1196222 (-) 1353 WP_328492217.1 hypothetical protein -
  OHS59_RS05255 (OHS59_05255) - 1196319..1197026 (-) 708 WP_328492218.1 DUF308 domain-containing protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 24158.88 Da        Isoelectric Point: 6.6535

>NTDB_id=649599 OHS59_RS05230 WP_328492213.1 1191767..1192432(+) (vraR) [Streptomyces sp. NBC_00414]
MTIRLLIVDDQELIRTGFRLFLQTQNDLEVVGEAADGHEALTQAAALRPDVVLMDIRMPRMDGVEATSRLTASGTSTRVL
VLTTYDLDEYVFGALRAGASGFLLKDASRERLLEAIRVVHAGEALLSPSITRRLIEDYATRTGPLRPRAKLLTGLTPREQ
EILLLVARGLSNPEIAAHLVVTEATVKSHIGSMFAKLHLRDRAQAVVFAYENGFVLPGTSG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=649599 OHS59_RS05230 WP_328492213.1 1191767..1192432(+) (vraR) [Streptomyces sp. NBC_00414]
ATGACCATCCGTCTTCTGATCGTCGACGACCAGGAACTGATCCGCACCGGCTTCCGGCTCTTCCTGCAGACCCAGAACGA
CCTTGAGGTCGTCGGCGAGGCCGCCGACGGCCACGAGGCGCTCACCCAGGCCGCCGCGCTGCGCCCCGACGTGGTCCTGA
TGGACATCCGCATGCCGCGCATGGACGGCGTCGAGGCCACCTCCCGGCTGACCGCCTCCGGAACCTCGACCCGGGTCCTG
GTCCTCACCACCTACGACCTGGACGAATACGTCTTCGGCGCGCTCCGGGCGGGCGCGTCGGGCTTCCTCCTCAAGGACGC
CTCACGCGAGCGCCTGCTGGAGGCGATCCGCGTCGTGCACGCAGGCGAGGCCCTGCTGTCGCCGTCGATCACCCGCAGGC
TGATCGAGGACTACGCCACCCGCACCGGACCGCTCCGGCCCCGGGCCAAACTGCTGACCGGTCTCACCCCCCGGGAACAG
GAGATCCTCCTCCTGGTGGCCAGGGGCCTGTCGAACCCGGAGATCGCCGCGCACCTGGTCGTGACCGAGGCGACGGTGAA
GAGCCACATCGGCAGCATGTTCGCCAAGCTCCATCTGCGTGACCGCGCCCAAGCGGTGGTGTTCGCGTACGAGAACGGCT
TCGTCCTCCCGGGCACCTCGGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(155-209)

Response regulator receiver domain (Response_reg)

(6-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.93

97.285

0.398
  degU Bacillus subtilis subsp. subtilis str. 168

38.117

100

0.385