Detailed information NTG0649542

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OHS82_RS18940
• Genome accession: NZ_CP107928
• Coordinates: 4431887..4433011 (+)
• Length: 374 a.a.
• NCBI ID: WP_057577693.1
• Uniprot ID: A0ABU0Q5M6
• Organism: Streptomyces sp. NBC_00425
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4426887..4438011

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OHS82_RS18925 (OHS82_18935)	-	4427425..4428231 (+)	807	WP_057577690.1	hypothetical protein	-
OHS82_RS18930 (OHS82_18940)	-	4428365..4430176 (-)	1812	WP_063894241.1	hypothetical protein	-
OHS82_RS18935 (OHS82_18945)	radA/sms	4430396..4431805 (+)	1410	WP_057577692.1	DNA repair protein RadA	Machinery gene
OHS82_RS18940 (OHS82_18950)	disA	4431887..4433011 (+)	1125	WP_057577693.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OHS82_RS18945 (OHS82_18955)	-	4433091..4433942 (-)	852	WP_328434189.1	hypothetical protein	-
OHS82_RS18950 (OHS82_18960)	-	4434180..4435118 (+)	939	WP_328434190.1	A/G-specific adenine glycosylase	-
OHS82_RS18955 (OHS82_18965)	-	4435520..4436062 (+)	543	WP_057577696.1	SigE family RNA polymerase sigma factor	-
OHS82_RS18960 (OHS82_18970)	-	4436137..4436781 (+)	645	WP_057578083.1	hypothetical protein	-
OHS82_RS18965 (OHS82_18975)	cseB	4436981..4437682 (+)	702	WP_057577697.1	two-component system response regulator CseB	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40065.83 Da
• Isoelectric Point: 5.0961

>NTDB_id=649542 OHS82_RS18940 WP_057577693.1 4431887..4433011(+) (disA) [Streptomyces sp. NBC_00425]
MAANDRAAAPGKSGGSSGSDGLMRAALSAVAPGTALRDGLERILRGNTGGLIVLGSDKTVEAMCTGGFVLNVEFAATRLR
ELCKLDGGIVVSSDLSKILRAGVQLVPDPMIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALHELDALTHAELLELSTVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFSSLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=649542 OHS82_RS18940 WP_057577693.1 4431887..4433011(+) (disA) [Streptomyces sp. NBC_00425]
GTGGCAGCCAACGACCGGGCGGCAGCTCCCGGAAAGTCCGGTGGGAGTTCCGGTTCCGACGGCCTGATGCGCGCCGCGCT
GAGCGCGGTGGCCCCCGGCACGGCCCTGCGCGACGGCCTGGAGAGGATCCTCCGCGGCAACACCGGCGGGCTGATCGTGC
TGGGCTCCGACAAGACGGTCGAAGCGATGTGCACGGGCGGGTTCGTCCTGAACGTGGAGTTCGCGGCCACGCGCCTGCGT
GAGCTGTGCAAGCTCGACGGCGGCATCGTGGTCTCCTCCGACCTGTCGAAGATCCTCCGGGCCGGCGTCCAGCTGGTGCC
CGATCCCATGATCCCCACGGAGGAGACCGGCACCCGGCACCGCACGGCGGACCGGGTCAGCAAGCAGGTCGGCTTCCCGG
TCGTCTCGGTCTCGCAGTCCATGCGCCTGATCGCCCTGTACGTCGACGGGCAGCGCCGGGTCCTGGAGGACTCCGCGGCG
ATCCTGTCCCGCGCGAACCAGGCGCTGGCCACCCTGGAGCGCTACAAACTCCGCCTGGACGAGGTCGCGGGAACGTTGTC
AGCGCTGGAGATCGAGGACCTGGTGACGGTCCGGGACGTCTCGGCGGTGGCCCAGCGACTGGAGATGGTGCGTCGCATCG
CCACCGAAATCGCCGAATACGTGGTCGAACTGGGCACGGACGGACGACTGCTCGCCCTCCAGCTCGACGAGCTGATCGCG
GGCGTGGAGCCGGAGCGCGAACTGGTGGTCCGGGACTACGTCCCCGAGCCGACGGCCAAGCGTTCCCGCACGGTCGACGA
GGCGCTGCACGAACTGGACGCGCTCACCCACGCCGAGCTCCTGGAACTGTCCACGGTCGCCCGCGCGCTGGGCTACACCG
GCTCCCCCGAGGCACTGGACTCGGCGGTGTCCCCACGCGGCTTCCGCCTGCTGGCGAAGGTGCCGCGCCTCCCCGGAGCC
ATCATCGACCGTCTCGTGGAGCACTTCAGCAGCCTGCAGAAGCTGCTCGCCGCGAGCGTCGACGACCTCCAGACGGTGGA
CGGCGTGGGCGAGGCGCGGGCCCGCAGCGTCCGCGAGGGCCTGTCCCGACTGGCCGAGTCCTCGATCCTGGAGCGTTACG
TCTAA

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.152	96.524	0.436