Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG389_RS06120 Genome accession   NZ_CP107924
Coordinates   1351477..1352127 (+) Length   216 a.a.
NCBI ID   WP_328297441.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00435     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1346477..1357127
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG389_RS06095 (OG389_06105) mug 1347172..1347732 (+) 561 WP_328297437.1 G/U mismatch-specific DNA glycosylase -
  OG389_RS06100 (OG389_06110) - 1347778..1348425 (+) 648 WP_328303550.1 HAD family hydrolase -
  OG389_RS06105 (OG389_06115) - 1348480..1349229 (-) 750 WP_328297438.1 ABC transporter permease -
  OG389_RS06110 (OG389_06120) - 1349259..1350170 (-) 912 WP_328297439.1 ATP-binding cassette domain-containing protein -
  OG389_RS06115 (OG389_06125) - 1350279..1351472 (+) 1194 WP_328297440.1 histidine kinase -
  OG389_RS06120 (OG389_06130) vraR 1351477..1352127 (+) 651 WP_328297441.1 response regulator transcription factor Regulator
  OG389_RS06125 (OG389_06135) - 1352184..1352678 (+) 495 WP_328297442.1 hypothetical protein -
  OG389_RS06130 (OG389_06140) istB 1352699..1353466 (-) 768 WP_328297443.1 IS21-like element helper ATPase IstB -
  OG389_RS06135 (OG389_06145) istA 1353463..1354881 (-) 1419 Protein_1225 IS21 family transposase -
  OG389_RS06140 (OG389_06150) - 1355145..1356302 (+) 1158 WP_328297444.1 ROK family transcriptional regulator -
  OG389_RS06145 (OG389_06155) - 1356402..1356860 (+) 459 WP_328297445.1 PH domain-containing protein -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23283.95 Da        Isoelectric Point: 4.9794

>NTDB_id=649437 OG389_RS06120 WP_328297441.1 1351477..1352127(+) (vraR) [Streptomyces sp. NBC_00435]
MPVTVLLVDDEPLVRAGLRAVLDAQPDIEVVGEAADGASVVPLVRQLRPDVVAMDVRMPLLDGIEATRAVLRSVDSPPKI
LVVTTFENDEYVYQALRAGADGFLLKRARPSEIVHAVRLVAEGETLLFPAAVRSLAAEYGNRQARTVLERAALTEREEAV
LRLMAKGLTNIEIARELIVGTETVKSHVSAILAKLGARDRTQAVITAYESGFVAPA

Nucleotide


Download         Length: 651 bp        

>NTDB_id=649437 OG389_RS06120 WP_328297441.1 1351477..1352127(+) (vraR) [Streptomyces sp. NBC_00435]
ATGCCGGTTACCGTACTGCTCGTCGACGACGAACCCCTGGTGCGCGCGGGTCTGCGCGCCGTCCTGGACGCCCAGCCCGA
CATCGAGGTGGTCGGTGAGGCGGCCGACGGCGCCTCGGTCGTCCCGCTCGTGCGGCAACTGCGGCCGGACGTCGTGGCGA
TGGACGTCCGGATGCCGCTGCTCGACGGGATCGAGGCGACCCGGGCGGTCCTGCGGTCCGTGGATTCGCCGCCCAAGATC
CTCGTGGTCACCACCTTCGAGAACGACGAGTACGTCTACCAGGCCCTGCGGGCGGGCGCGGACGGGTTCCTGCTGAAGCG
GGCCCGCCCGTCGGAGATCGTGCACGCGGTACGGCTGGTGGCCGAGGGCGAGACGCTTCTCTTCCCCGCGGCGGTGCGGT
CGCTGGCCGCCGAGTACGGGAACCGGCAGGCGCGCACGGTGCTGGAGCGGGCGGCGCTGACCGAGCGTGAGGAGGCCGTC
CTCCGGCTGATGGCCAAAGGCCTGACCAACATCGAGATCGCCCGCGAGCTGATCGTGGGCACCGAGACGGTGAAGTCCCA
CGTCAGTGCGATCCTGGCGAAGCTGGGCGCGCGGGACCGGACCCAGGCCGTCATCACCGCGTACGAATCGGGATTCGTCG
CCCCCGCCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(152-207)

Response regulator receiver domain (Response_reg)

(5-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.121

99.074

0.407
  degU Bacillus subtilis subsp. subtilis str. 168

35.714

100

0.37