Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHB13_RS06750 Genome accession   NZ_CP107921
Coordinates   1503321..1503980 (-) Length   219 a.a.
NCBI ID   WP_323183857.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00440     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1498321..1508980
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHB13_RS06720 (OHB13_06730) - 1498935..1499438 (+) 504 WP_266858388.1 HNH endonuclease -
  OHB13_RS06725 (OHB13_06735) - 1499513..1500454 (-) 942 WP_266858387.1 SPFH domain-containing protein -
  OHB13_RS06730 (OHB13_06740) - 1500537..1500965 (-) 429 WP_328376242.1 NfeD family protein -
  OHB13_RS06735 (OHB13_06745) - 1501025..1501822 (-) 798 WP_266858383.1 ABC transporter ATP-binding protein -
  OHB13_RS06740 (OHB13_06750) - 1501945..1502733 (+) 789 WP_266858381.1 hypothetical protein -
  OHB13_RS06745 (OHB13_06755) - 1502936..1503175 (-) 240 WP_266858379.1 chaplin -
  OHB13_RS06750 (OHB13_06760) vraR 1503321..1503980 (-) 660 WP_323183857.1 response regulator transcription factor Regulator
  OHB13_RS06755 (OHB13_06765) - 1503973..1505124 (-) 1152 WP_328376247.1 GAF domain-containing sensor histidine kinase -
  OHB13_RS06760 (OHB13_06770) - 1505376..1506074 (+) 699 WP_328376249.1 SDR family oxidoreductase -
  OHB13_RS06765 (OHB13_06775) - 1506071..1507168 (+) 1098 WP_328376250.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OHB13_RS06770 (OHB13_06780) - 1507431..1508174 (+) 744 WP_266858372.1 transglycosylase SLT domain-containing protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 23498.93 Da        Isoelectric Point: 5.3956

>NTDB_id=649366 OHB13_RS06750 WP_323183857.1 1503321..1503980(-) (vraR) [Streptomyces sp. NBC_00440]
MADTAPRPKAAIRVLLVDDHQVVRRGLRTFLEIQDDIEVVGEAPDGEQGVAAAEELRPDIVLMDIKMPGMDGIEALRRLR
ELANPARVLVVTSFTEQRTVVPALRAGASGYVYKDVDPEALADAIRSVHAGHVLLQPEVAGALLSPEPGGGQGRGTALTE
REREVLGLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRNGAAG

Nucleotide


Download         Length: 660 bp        

>NTDB_id=649366 OHB13_RS06750 WP_323183857.1 1503321..1503980(-) (vraR) [Streptomyces sp. NBC_00440]
GTGGCTGACACCGCACCCAGGCCGAAGGCGGCCATCCGCGTGCTGCTCGTCGACGACCACCAGGTGGTCAGGCGGGGCCT
GCGCACCTTTCTGGAGATCCAGGACGACATCGAGGTCGTGGGCGAGGCACCGGACGGGGAGCAGGGGGTGGCCGCCGCCG
AGGAGCTGCGCCCCGACATCGTCCTGATGGACATCAAGATGCCGGGCATGGACGGTATCGAGGCGCTGCGCAGGCTCAGG
GAGCTGGCCAATCCGGCGAGGGTGCTGGTGGTCACCAGCTTCACCGAGCAGCGCACCGTGGTTCCCGCCCTGCGCGCGGG
TGCGTCGGGCTATGTGTACAAGGACGTCGACCCGGAGGCGCTGGCCGACGCGATCCGCTCGGTCCACGCCGGGCACGTCC
TGCTCCAGCCCGAAGTGGCCGGGGCGCTGCTCTCCCCGGAGCCGGGCGGCGGCCAGGGGAGGGGCACCGCGCTCACCGAG
CGGGAACGCGAGGTGCTGGGGCTGATCGCCGACGGACGCTCCAACCGGGAGATCGCGCGAGCACTGGTCCTCTCCGAGAA
GACCGTCAAGACGCATGTGTCGAACATCCTGATGAAACTGGACCTCGCCGACCGGACCCAGGCGGCGCTCTGGGCGGTAC
GGAACGGGGCGGCGGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(14-126)

Bacterial regulatory proteins, luxR family (GerE)

(157-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.66

94.064

0.42
  degU Bacillus subtilis subsp. subtilis str. 168

37.557

100

0.379