Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHB13_RS03645 Genome accession   NZ_CP107921
Coordinates   805055..805705 (+) Length   216 a.a.
NCBI ID   WP_328375574.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00440     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 800055..810705
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHB13_RS03620 (OHB13_03625) mug 801013..801567 (+) 555 WP_266859365.1 G/U mismatch-specific DNA glycosylase -
  OHB13_RS03625 (OHB13_03630) - 801649..802092 (-) 444 WP_328375566.1 hypothetical protein -
  OHB13_RS03630 (OHB13_03635) - 802138..802881 (-) 744 WP_328375568.1 ABC transporter permease -
  OHB13_RS03635 (OHB13_03640) - 802885..803817 (-) 933 WP_328375570.1 ATP-binding cassette domain-containing protein -
  OHB13_RS03640 (OHB13_03645) - 803926..805050 (+) 1125 WP_328375572.1 histidine kinase -
  OHB13_RS03645 (OHB13_03650) vraR 805055..805705 (+) 651 WP_328375574.1 response regulator transcription factor Regulator
  OHB13_RS03650 (OHB13_03655) - 805797..806957 (+) 1161 WP_266859362.1 ROK family protein -
  OHB13_RS03655 (OHB13_03660) - 807020..807787 (-) 768 WP_266859360.1 GntR family transcriptional regulator -
  OHB13_RS03660 (OHB13_03665) - 808025..808909 (-) 885 WP_328375576.1 RNA polymerase sigma-70 factor -
  OHB13_RS03665 (OHB13_03670) - 809111..809941 (+) 831 WP_328375577.1 alpha/beta hydrolase -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 22875.59 Da        Isoelectric Point: 5.8510

>NTDB_id=649362 OHB13_RS03645 WP_328375574.1 805055..805705(+) (vraR) [Streptomyces sp. NBC_00440]
MPISVLLVDDEPLVRAGLRAVLEAQGDIQVVGEAADGAAVVPLVRQLRPDVVAMDVRMPLLDGIAATRAVLRAFQPPPKI
LVVTTFENDEYVYQALRAGADGFLLKRARPAEIVHAVRLIAEGESLLFPAAVRALAAEYGNSAAREALDRAALTEREAAV
LRLMARGLSNAEIAGRLVIGIETVKSHVSAVLAKLGARDRTQAVIAAYESGFVAPA

Nucleotide


Download         Length: 651 bp        

>NTDB_id=649362 OHB13_RS03645 WP_328375574.1 805055..805705(+) (vraR) [Streptomyces sp. NBC_00440]
GTGCCGATCTCTGTGCTGCTTGTCGACGACGAACCTCTCGTACGTGCCGGCCTGCGCGCCGTACTTGAGGCCCAGGGCGA
CATTCAGGTGGTGGGCGAGGCCGCTGACGGTGCGGCCGTGGTCCCGCTGGTACGCCAGTTGCGCCCTGACGTGGTGGCCA
TGGATGTGCGGATGCCCCTGCTCGACGGCATCGCGGCCACCCGGGCAGTGCTGCGGGCCTTTCAGCCGCCGCCGAAGATC
CTGGTCGTGACGACCTTCGAGAACGACGAGTACGTCTATCAGGCACTGCGCGCGGGTGCGGACGGGTTTCTGCTGAAGCG
GGCCCGGCCCGCCGAGATCGTCCACGCGGTACGGCTGATCGCCGAGGGCGAGTCTCTGCTGTTCCCGGCCGCGGTCCGAG
CCCTCGCGGCCGAGTACGGCAACAGCGCGGCGCGAGAAGCACTGGACCGGGCGGCTCTGACCGAACGGGAAGCCGCAGTG
CTCCGGCTGATGGCGCGCGGTCTGTCGAACGCGGAGATCGCGGGCCGGCTCGTCATCGGGATCGAAACGGTGAAGTCCCA
CGTCAGCGCTGTGCTGGCGAAGTTGGGGGCCCGGGACCGTACGCAAGCGGTGATTGCCGCGTACGAGTCGGGGTTCGTCG
CGCCCGCCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-118)

Bacterial regulatory proteins, luxR family (GerE)

(152-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.315

98.611

0.407
  degU Bacillus subtilis subsp. subtilis str. 168

35.398

100

0.37