Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHB13_RS02425 Genome accession   NZ_CP107921
Coordinates   539578..540243 (-) Length   221 a.a.
NCBI ID   WP_266859760.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00440     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 534578..545243
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHB13_RS02405 (OHB13_02410) - 535357..536142 (+) 786 WP_328375227.1 helix-turn-helix domain-containing protein -
  OHB13_RS02410 (OHB13_02415) - 536203..537417 (-) 1215 WP_266859766.1 ROK family protein -
  OHB13_RS02415 (OHB13_02420) - 537505..538728 (+) 1224 WP_328375230.1 MFS transporter -
  OHB13_RS02420 (OHB13_02425) - 538770..539516 (+) 747 WP_328375231.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  OHB13_RS02425 (OHB13_02430) vraR 539578..540243 (-) 666 WP_266859760.1 response regulator transcription factor Regulator
  OHB13_RS02430 (OHB13_02435) - 540240..541460 (-) 1221 WP_328375236.1 sensor histidine kinase -
  OHB13_RS02435 (OHB13_02440) - 541769..542464 (-) 696 WP_266859756.1 TetR/AcrR family transcriptional regulator -
  OHB13_RS02440 (OHB13_02445) - 542598..543047 (+) 450 WP_328375238.1 nitroreductase/quinone reductase family protein -
  OHB13_RS02445 (OHB13_02450) - 543171..544487 (-) 1317 WP_266859752.1 geranylgeranyl reductase family protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23752.57 Da        Isoelectric Point: 4.7696

>NTDB_id=649360 OHB13_RS02425 WP_266859760.1 539578..540243(-) (vraR) [Streptomyces sp. NBC_00440]
MIRVLLADDQSLVRAGFRALLGAQPDIEVTGEAADGTEALALVRELRPDVVLMDIRMPLLDGLAATRKITADPELDGIKV
VMLTTFELDEYVFEAIRSGASGFLVKDTEPEELLRAVRAVVDGDALLSPGVTRRLIAEFAARSKEPATAVGLGGLTERER
EVMALVGIGLSNDEIARRLVVSPLTAKTHVSRAMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=649360 OHB13_RS02425 WP_266859760.1 539578..540243(-) (vraR) [Streptomyces sp. NBC_00440]
GTGATCCGTGTCCTGCTCGCCGACGACCAGTCCCTGGTCAGAGCCGGATTCCGGGCGCTGCTCGGGGCCCAGCCGGACAT
CGAGGTGACCGGCGAGGCCGCCGACGGCACCGAGGCGCTGGCACTGGTACGGGAACTGCGGCCGGACGTCGTGCTGATGG
ACATCCGGATGCCGTTGCTCGACGGCCTGGCCGCCACCAGGAAGATCACCGCGGACCCGGAGCTGGACGGGATCAAGGTG
GTCATGCTCACCACCTTCGAGCTCGACGAGTACGTCTTCGAGGCGATCCGCTCCGGAGCCTCCGGCTTCCTGGTCAAGGA
CACCGAACCGGAAGAACTGCTGCGCGCGGTACGGGCGGTGGTCGACGGCGACGCGCTGCTCTCGCCGGGCGTGACGCGCA
GGCTCATCGCCGAGTTCGCCGCGCGCTCCAAGGAACCGGCCACCGCCGTCGGCCTCGGCGGACTCACCGAACGCGAGCGG
GAGGTGATGGCCCTGGTCGGTATCGGCCTCTCCAACGACGAGATCGCCCGCAGGCTCGTGGTCAGCCCGCTCACCGCCAA
GACCCACGTCAGCCGCGCCATGGTGAAGCTCGGTGCCCGCGACCGGGCCCAGCTCGTGGTCCTGGCGTACGAGTCGGGGC
TGGTGCGCCCCGGCTGGCTGGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(155-209)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.07

97.285

0.38
  degU Bacillus subtilis subsp. subtilis str. 168

36.283

100

0.371