Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   H020_RS0106030 Genome accession   NZ_AKVY01000001
Coordinates   1160045..1161394 (-) Length   449 a.a.
NCBI ID   WP_000886219.1    Uniprot ID   -
Organism   Streptococcus pneumoniae TIGR4     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1155045..1166394
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H020_RS0106010 - 1156699..1158570 (-) 1872 WP_000150986.1 Eco57I restriction-modification methylase domain-containing protein -
  H020_RS0106015 - 1158645..1158899 (-) 255 WP_001809704.1 type II toxin-antitoxin system RelE family toxin -
  H020_RS0106020 relB 1158901..1159143 (-) 243 WP_000208080.1 type II toxin-antitoxin system RelB family antitoxin -
  H020_RS0106025 vicX 1159234..1160043 (-) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  H020_RS0106030 micB 1160045..1161394 (-) 1350 WP_000886219.1 cell wall metabolism sensor histidine kinase VicK Regulator
  H020_RS0106035 micA 1161387..1162091 (-) 705 WP_000722076.1 response regulator YycF Regulator
  H020_RS0106040 mutY 1162147..1163322 (-) 1176 WP_000886146.1 A/G-specific adenine glycosylase -
  H020_RS14530 - 1163419..1163544 (+) 126 WP_001818232.1 hypothetical protein -
  H020_RS0106045 - 1163650..1165320 (-) 1671 WP_000845295.1 formate--tetrahydrofolate ligase -
  H020_RS0106050 coaB 1165550..1166239 (+) 690 WP_000699501.1 phosphopantothenate--cysteine ligase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51698.39 Da        Isoelectric Point: 4.9706

>NTDB_id=64932 H020_RS0106030 WP_000886219.1 1160045..1161394(-) (micB) [Streptococcus pneumoniae TIGR4]
MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQVNQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSE
VIRLTQENLEQESKRLNSILFYMTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALC
ETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSHLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIW
MEIDTDKMTQVVDNILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSRAQGGTGLG
LSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=64932 H020_RS0106030 WP_000886219.1 1160045..1161394(-) (micB) [Streptococcus pneumoniae TIGR4]
ATGCTTGATTTACTGAAACAAACCATTTTTACCAGAGATTTTATCTTTATCCTGATTTTGTTAGGTTTCATCCTTGTTGT
GACCCTCTTATTACTGGAAAATAGACGTGATAATATTCAGTTGAAGCAAGTCAATCAAAAGGTTAAAGATTTGATTGCAG
GAGATTATTCCAAGGTTCTTGATATGCAAGGTGGGTCTGAAATCACCAATATTACCAATAATTTGAATGACTTGTCGGAG
GTTATTCGTCTCACTCAGGAAAATCTAGAACAAGAGAGTAAGAGGCTAAATAGTATTCTGTTTTATATGACAGATGGGGT
TCTTGCGACTAACCGTCGGGGTCAGATTATCATGATTAACGATACAGCCAAGAAGCAACTGGGGTTGGTTAAGGAAGATG
TTCTGAATAGAAGCATTTTGGAATTGCTCAAGATAGAAGAAAACTATGAATTGCGTGATTTGATTACCCAAAGTCCAGAA
TTGTTGCTAGATTCCCAAGATATCAATGGCGAATATTTGAACCTTCGAGTTCGCTTTGCCTTGATACGTCGAGAGTCTGG
CTTTATTTCAGGTTTGGTGGCTGTTTTGCATGATACGACGGAGCAGGAGAAGGAAGAACGCGAACGAAGACTCTTTGTTT
CCAATGTTAGCCATGAGTTACGGACTCCTCTGACTAGCGTAAAATCCTATCTTGAAGCCTTGGATGAGGGGGCTTTGTGT
GAAACTGTAGCACCAGACTTTATCAAGGTTTCTCTTGATGAGACCAACCGTATGATGCGCATGGTGACGGATCTCCTCCA
TCTTTCACGTATTGATAATGCTACCAGTCACCTAGATGTGGAACTGATTAACTTCACTGCTTTTATTACCTTTATCCTCA
ATCGTTTTGACAAGATGAAAGGACAGGAAAAGGAGAAAAAATATGAGTTGGTGAGAGATTATCCCATCAATTCTATCTGG
ATGGAAATTGATACAGATAAGATGACGCAGGTTGTCGACAATATTTTAAATAATGCTATTAAGTATTCGCCAGATGGGGG
TAAAATCACTGTCAGAATGAAGACAACTGAAGACCAGATGATTTTATCCATTTCTGACCACGGTTTGGGGATTCCTAAGC
AGGATTTACCACGTATCTTTGACCGTTTCTATCGTGTGGATCGTGCTAGAAGTCGTGCACAAGGTGGTACAGGTCTAGGA
CTGTCTATCGCTAAAGAAATTATCAAACAACATAAGGGCTTTATTTGGGCCAAGAGTGAATACGGCAAGGGTTCAACCTT
TACCATTGTACTCCCTTATGATAAGGATGCAGTGAAAGAAGAAGTATGGGAGGATGAAGTAGAAGACTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(98-198)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

99.555

100

0.996
  vicK Streptococcus mutans UA159

69.9

89.532

0.626

Multiple sequence alignment