Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG432_RS18285 Genome accession   NZ_CP107918
Coordinates   4058646..4059311 (+) Length   221 a.a.
NCBI ID   WP_328312010.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00442     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4053646..4064311
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG432_RS18260 (OG432_18260) - 4053752..4054633 (+) 882 WP_328312006.1 alpha/beta hydrolase -
  OG432_RS18265 (OG432_18265) - 4054630..4055820 (-) 1191 WP_328312007.1 SGNH/GDSL hydrolase family protein -
  OG432_RS18270 (OG432_18270) - 4055832..4056401 (-) 570 WP_328312008.1 WHG domain-containing protein -
  OG432_RS18275 (OG432_18275) - 4056543..4057040 (+) 498 WP_328312009.1 FBP domain-containing protein -
  OG432_RS18280 (OG432_18280) - 4057267..4058649 (+) 1383 WP_328315151.1 histidine kinase -
  OG432_RS18285 (OG432_18285) vraR 4058646..4059311 (+) 666 WP_328312010.1 response regulator transcription factor Regulator
  OG432_RS18290 (OG432_18290) - 4059412..4059680 (+) 269 Protein_3602 ISAzo13 family transposase -
  OG432_RS18295 (OG432_18295) - 4059735..4060526 (-) 792 WP_328312011.1 ABC transporter permease -
  OG432_RS18300 (OG432_18300) - 4060523..4061485 (-) 963 WP_328312012.1 ATP-binding cassette domain-containing protein -
  OG432_RS18305 (OG432_18305) - 4061694..4062428 (+) 735 WP_328312013.1 helix-turn-helix domain-containing protein -
  OG432_RS18310 (OG432_18310) - 4062647..4063489 (-) 843 Protein_3606 IS5 family transposase -
  OG432_RS18315 (OG432_18315) - 4063688..4064014 (-) 327 WP_328312014.1 rhodanese-like domain-containing protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23923.51 Da        Isoelectric Point: 4.6475

>NTDB_id=649256 OG432_RS18285 WP_328312010.1 4058646..4059311(+) (vraR) [Streptomyces sp. NBC_00442]
MTIKVLIVDDQMMVREGFSVLLGAQPDIEVVGEAVDGREAVAQVQALRPDVVLMDIRMPHMNGIEATREIVAADDSSKVL
VLTTFDLDEYVYQALRAGASGFLLKDASARQLAEGVRVVASGEALLAPSVTRRLINEFARVLPAQRGGSAGVGQVEELTD
RETEVLVLIAQGLSNQEIAERLVVAESTIKTHVSRVLVKLGLRDRTQAAVYAYETRLVTPS

Nucleotide


Download         Length: 666 bp        

>NTDB_id=649256 OG432_RS18285 WP_328312010.1 4058646..4059311(+) (vraR) [Streptomyces sp. NBC_00442]
GTGACGATCAAGGTCCTCATCGTCGACGACCAGATGATGGTGCGCGAGGGATTCTCCGTACTGCTCGGCGCGCAGCCGGA
CATCGAGGTCGTCGGTGAGGCGGTCGACGGCCGCGAGGCGGTGGCCCAGGTGCAGGCGCTCCGCCCCGACGTGGTCCTGA
TGGACATCCGCATGCCCCACATGAACGGCATCGAGGCGACGCGGGAGATCGTCGCGGCGGACGACTCGTCGAAGGTGCTC
GTCCTGACCACGTTCGACCTCGACGAGTACGTGTACCAGGCGCTGCGGGCCGGTGCGTCCGGCTTCCTCCTGAAGGACGC
ATCCGCGCGTCAACTCGCCGAGGGGGTAAGGGTGGTGGCGTCCGGGGAGGCGCTGCTCGCGCCCTCGGTGACGCGGCGCC
TGATCAACGAGTTCGCGCGGGTCCTGCCGGCGCAGCGGGGTGGCTCCGCCGGGGTGGGGCAGGTGGAGGAGCTCACGGAT
CGTGAGACGGAGGTGCTCGTCCTGATCGCTCAGGGGTTGTCCAACCAGGAGATCGCGGAGCGGCTGGTTGTGGCGGAGTC
GACGATCAAGACGCACGTCAGTCGGGTGCTGGTGAAACTTGGTCTCCGTGACCGTACGCAGGCGGCGGTCTACGCCTACG
AAACCCGCCTGGTAACCCCGTCCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-115)

Bacterial regulatory proteins, luxR family (GerE)

(158-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

45.413

98.643

0.448
  degU Bacillus subtilis subsp. subtilis str. 168

43.556

100

0.443