Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHO27_RS33375 Genome accession   NZ_CP107917
Coordinates   7334655..7335296 (+) Length   213 a.a.
NCBI ID   WP_328428680.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00443     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7329655..7340296
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHO27_RS33355 (OHO27_33335) - 7330362..7331123 (-) 762 WP_328428676.1 transglycosylase SLT domain-containing protein -
  OHO27_RS33360 (OHO27_33340) - 7331423..7332580 (-) 1158 WP_328428677.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OHO27_RS33365 (OHO27_33345) - 7332577..7333275 (-) 699 WP_328428678.1 SDR family oxidoreductase -
  OHO27_RS33370 (OHO27_33350) - 7333517..7334662 (+) 1146 WP_328428679.1 GAF domain-containing sensor histidine kinase -
  OHO27_RS33375 (OHO27_33355) vraR 7334655..7335296 (+) 642 WP_328428680.1 response regulator transcription factor Regulator
  OHO27_RS33380 (OHO27_33360) chpE 7335465..7335710 (+) 246 WP_328428681.1 chaplin ChpE -
  OHO27_RS33385 (OHO27_33365) - 7335921..7336709 (-) 789 WP_328428682.1 hypothetical protein -
  OHO27_RS33390 (OHO27_33370) - 7336848..7337645 (+) 798 WP_328428683.1 ABC transporter ATP-binding protein -
  OHO27_RS33395 (OHO27_33375) - 7337740..7338171 (+) 432 WP_328428684.1 NfeD family protein -
  OHO27_RS33400 (OHO27_33380) - 7338303..7339250 (+) 948 WP_328428685.1 SPFH domain-containing protein -
  OHO27_RS33405 (OHO27_33385) - 7339390..7339896 (-) 507 WP_328428686.1 HNH endonuclease -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 22897.17 Da        Isoelectric Point: 5.1490

>NTDB_id=649196 OHO27_RS33375 WP_328428680.1 7334655..7335296(+) (vraR) [Streptomyces sp. NBC_00443]
MADAIKVLLVDDHQVVRRGLRTFLEVQDDIEVVGEAADGAEGVARAEELKPDVVLMDVKMPGMDGVDALRKLRELDNPAR
VLIVTSFTEQRTVIPALRAGAAGYVYKDVDPDALAGAIRSVHAGHILLQPEVAGALLSQEEANSGQGRAGSLTDREREVL
GLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGVTG

Nucleotide


Download         Length: 642 bp        

>NTDB_id=649196 OHO27_RS33375 WP_328428680.1 7334655..7335296(+) (vraR) [Streptomyces sp. NBC_00443]
GTGGCTGACGCAATCAAGGTGCTGCTCGTCGACGACCACCAGGTCGTCCGCCGGGGCCTGCGCACCTTCCTCGAAGTACA
GGACGACATCGAGGTCGTGGGTGAGGCCGCCGACGGCGCCGAGGGAGTGGCCCGCGCCGAGGAACTCAAGCCCGACGTGG
TGCTGATGGACGTCAAGATGCCGGGCATGGACGGAGTCGACGCCCTGCGTAAGCTCCGCGAACTCGACAACCCCGCGCGC
GTGCTGATCGTCACCAGCTTCACCGAACAGCGCACGGTGATCCCCGCCCTGCGCGCGGGCGCCGCCGGTTACGTCTACAA
GGACGTGGACCCGGACGCCCTCGCCGGCGCCATCCGCTCCGTACACGCCGGGCACATCCTGCTCCAACCCGAGGTCGCGG
GCGCCTTGCTGTCCCAGGAGGAGGCCAACTCGGGGCAGGGAAGAGCCGGCTCGCTGACGGACCGCGAGCGCGAGGTCCTC
GGCCTGATCGCCGACGGCCGCTCGAACCGCGAGATCGCGCGGGCCCTGGTCCTCTCCGAGAAGACCGTCAAGACACACGT
CTCAAACATCTTGATGAAGCTCGACCTGGCAGACCGCACACAGGCCGCCCTGTGGGCCGTACGCCATGGCGTGACCGGCT
GA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(151-206)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

47.17

99.531

0.469
  degU Bacillus subtilis subsp. subtilis str. 168

38.462

100

0.399