Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   H020_RS0101825 Genome accession   NZ_AKVY01000001
Coordinates   355614..356303 (+) Length   229 a.a.
NCBI ID   WP_000518018.1    Uniprot ID   -
Organism   Streptococcus pneumoniae TIGR4     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 350614..361303
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H020_RS0101800 gpsB 350723..351052 (+) 330 WP_000146522.1 cell division regulator GpsB -
  H020_RS0101810 - 351538..352695 (+) 1158 WP_000711388.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  H020_RS0101815 mapZ 352708..354102 (+) 1395 WP_000039291.1 cell division site-positioning protein MapZ -
  H020_RS0101820 gndA 354178..355602 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  H020_RS0101825 covR 355614..356303 (+) 690 WP_000518018.1 response regulator transcription factor Regulator
  H020_RS0101830 cbpC 356402..357424 (+) 1023 WP_000771084.1 choline-binding protein CbpC -
  H020_RS0101835 cbpJ 357442..358440 (+) 999 WP_000698047.1 choline-binding protein CbpJ -
  H020_RS0101840 - 358558..359790 (-) 1233 WP_000765691.1 MFS transporter -
  H020_RS11625 - 359833..360708 (-) 876 WP_010963214.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26898.22 Da        Isoelectric Point: 6.9836

>NTDB_id=64915 H020_RS0101825 WP_000518018.1 355614..356303(+) (covR) [Streptococcus pneumoniae TIGR4]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=64915 H020_RS0101825 WP_000518018.1 355614..356303(+) (covR) [Streptococcus pneumoniae TIGR4]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACACGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACTGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment