Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA71_RS24495 Genome accession   NZ_CP107916
Coordinates   5328042..5328707 (-) Length   221 a.a.
NCBI ID   WP_328439474.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00444     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5323042..5333707
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA71_RS24460 (OHA71_24455) - 5323462..5323647 (-) 186 WP_328439467.1 DUF397 domain-containing protein -
  OHA71_RS24465 (OHA71_24460) - 5323647..5324498 (-) 852 WP_328439468.1 helix-turn-helix transcriptional regulator -
  OHA71_RS24470 (OHA71_24465) - 5324726..5325133 (+) 408 WP_328439469.1 ATP-binding protein -
  OHA71_RS24475 (OHA71_24470) - 5325163..5325300 (-) 138 WP_328439470.1 hypothetical protein -
  OHA71_RS24480 (OHA71_24475) - 5325549..5326400 (+) 852 WP_328439471.1 GntR family transcriptional regulator -
  OHA71_RS24485 (OHA71_24480) - 5326427..5327254 (-) 828 WP_328439472.1 class I SAM-dependent methyltransferase -
  OHA71_RS24490 (OHA71_24485) - 5327327..5327929 (+) 603 WP_328439473.1 TetR/AcrR family transcriptional regulator -
  OHA71_RS24495 (OHA71_24490) vraR 5328042..5328707 (-) 666 WP_328439474.1 response regulator transcription factor Regulator
  OHA71_RS24500 (OHA71_24495) - 5328704..5330044 (-) 1341 WP_328360032.1 histidine kinase -
  OHA71_RS24505 (OHA71_24500) - 5330168..5330841 (-) 674 Protein_4875 response regulator transcription factor -
  OHA71_RS24510 (OHA71_24505) - 5330838..5332178 (-) 1341 WP_328372094.1 sensor histidine kinase -
  OHA71_RS24515 (OHA71_24510) - 5332318..5333505 (-) 1188 WP_328442385.1 acyltransferase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23963.63 Da        Isoelectric Point: 4.6082

>NTDB_id=649070 OHA71_RS24495 WP_328439474.1 5328042..5328707(-) (vraR) [Streptomyces sp. NBC_00444]
MTIRVLIADDQMMVREGFSVLLNAMPDIEVVGEAVNGREAVDRVRELSPDVVLMDIRMPELNGIEATREIVAADDAAKVL
VLTTFDLDEYVYQALRAGASGFLLKDASARQLAEGVRVVASGEALLAPSVTKRLITEFSKLSEAPRAMSTAHAAYGELTE
RETEVLVLIAQGLSNAEIAERLVVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=649070 OHA71_RS24495 WP_328439474.1 5328042..5328707(-) (vraR) [Streptomyces sp. NBC_00444]
ATGACCATCCGCGTGCTGATCGCGGACGACCAGATGATGGTCCGCGAGGGCTTCTCGGTCCTGCTGAACGCGATGCCGGA
CATCGAGGTCGTCGGCGAGGCCGTCAACGGCCGGGAGGCGGTGGACCGAGTCCGCGAACTGTCCCCGGACGTCGTGCTGA
TGGACATCCGCATGCCCGAGCTGAACGGCATCGAGGCGACCCGGGAGATCGTCGCGGCCGACGACGCGGCGAAGGTGCTG
GTGCTGACCACCTTCGACCTGGACGAATACGTCTACCAGGCGCTGCGCGCAGGAGCCTCCGGCTTCCTCCTCAAGGACGC
CTCGGCCCGCCAACTCGCCGAGGGCGTACGGGTGGTGGCGTCCGGTGAGGCCCTCCTCGCCCCCTCCGTCACCAAGCGCC
TGATCACCGAGTTCTCCAAACTGTCCGAGGCCCCGCGCGCCATGTCCACCGCCCACGCGGCGTACGGCGAACTGACCGAA
CGGGAGACGGAGGTCCTGGTCCTGATCGCCCAGGGCCTGTCGAACGCGGAGATCGCCGAGCGCCTGGTGGTGGCGGAGTC
GACCATCAAGACCCACGTCAGCCGAATCCTGGTAAAGCTCGGCCTCAGAGACCGCACGCAGGCAGCGGTGTTCGCGTACG
AGGCGCGGCTGGTGACGCCGGGTTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-115)

Bacterial regulatory proteins, luxR family (GerE)

(158-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.037

98.643

0.434
  degU Bacillus subtilis subsp. subtilis str. 168

43.318

98.19

0.425