Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG800_RS10980 Genome accession   NZ_CP107914
Coordinates   2389824..2390471 (+) Length   215 a.a.
NCBI ID   WP_328353350.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00445     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2384824..2395471
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG800_RS10945 (OG800_10940) - 2385680..2385982 (-) 303 WP_328353329.1 hypothetical protein -
  OG800_RS10950 (OG800_10945) - 2386027..2386500 (-) 474 WP_328353332.1 hypothetical protein -
  OG800_RS10955 (OG800_10950) - 2386497..2386733 (-) 237 WP_328372758.1 hypothetical protein -
  OG800_RS10960 (OG800_10955) - 2386777..2386956 (-) 180 Protein_2185 helix-turn-helix domain-containing protein -
  OG800_RS10965 (OG800_10960) - 2387065..2387505 (-) 441 WP_328353341.1 DUF6069 family protein -
  OG800_RS10970 (OG800_10965) lgt 2387536..2388402 (-) 867 WP_328353344.1 prolipoprotein diacylglyceryl transferase -
  OG800_RS10975 (OG800_10970) - 2388580..2389827 (+) 1248 WP_328353347.1 sensor histidine kinase -
  OG800_RS10980 (OG800_10975) vraR 2389824..2390471 (+) 648 WP_328353350.1 response regulator transcription factor Regulator
  OG800_RS10985 (OG800_10980) - 2391212..2392903 (+) 1692 WP_328353353.1 carboxylesterase family protein -
  OG800_RS10990 (OG800_10985) - 2393286..2394650 (+) 1365 WP_328353356.1 aminomethyl transferase family protein -

Sequence

Protein


Download         Length: 215 a.a.        Molecular weight: 22358.59 Da        Isoelectric Point: 6.7588

>NTDB_id=648920 OG800_RS10980 WP_328353350.1 2389824..2390471(+) (vraR) [Streptomyces sp. NBC_00445]
MSTSTTPPIRVLLADDHPVVRDGLAAVLATQPDLTVVGEAATGAEAVRRTASLAPDVVLMDLQMPDMDSTAATAAIRAAH
PEVRVLVLTTYDTDADITAAVDAGAVGYLLKDTGRHELCEAVRTAARGGAALSPSVAAKVLAHMRGDRSAGLSGRELEVL
SAVARGQSNKQIARALRLSEATVKTHLLHIYTKLDVADRTAAVTAALGRGIIRID

Nucleotide


Download         Length: 648 bp        

>NTDB_id=648920 OG800_RS10980 WP_328353350.1 2389824..2390471(+) (vraR) [Streptomyces sp. NBC_00445]
ATGAGCACTTCGACCACTCCCCCGATCCGGGTCCTCCTCGCAGACGACCACCCCGTGGTCCGCGACGGGCTGGCCGCCGT
GCTGGCCACCCAGCCCGACCTCACGGTCGTCGGCGAAGCCGCCACCGGAGCCGAGGCAGTGCGCCGGACCGCGTCACTGG
CACCCGATGTCGTCCTGATGGACCTGCAGATGCCCGACATGGACAGCACCGCCGCGACCGCCGCTATCCGCGCCGCCCAC
CCCGAGGTGCGGGTCCTCGTCCTGACCACCTACGACACGGACGCCGACATCACCGCAGCCGTCGACGCCGGCGCGGTCGG
CTACCTGCTCAAGGACACCGGACGACACGAGCTGTGCGAGGCCGTGCGTACCGCGGCCCGGGGAGGAGCGGCACTGTCCC
CCTCGGTGGCCGCCAAGGTCCTCGCCCATATGCGCGGCGACCGGAGTGCCGGGCTGTCCGGCCGGGAACTCGAAGTTCTG
TCGGCCGTGGCCCGCGGGCAGAGCAACAAGCAGATCGCCCGCGCCCTGCGCCTGTCCGAGGCAACGGTCAAGACCCATCT
GCTGCACATCTACACCAAGCTCGACGTCGCCGACCGCACCGCCGCCGTCACCGCCGCACTGGGCCGCGGAATCATCCGCA
TCGACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(11-123)

Bacterial regulatory proteins, luxR family (GerE)

(152-205)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

42.029

96.279

0.405
  degU Bacillus subtilis subsp. subtilis str. 168

34.667

100

0.363