Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   L2Y54_RS20975 Genome accession   NZ_CP091244
Coordinates   4245333..4246766 (+) Length   477 a.a.
NCBI ID   WP_236498829.1    Uniprot ID   -
Organism   Thiothrix winogradskyi strain CT3     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 4240333..4251766
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L2Y54_RS20960 (L2Y54_20960) - 4241375..4241713 (-) 339 WP_236498824.1 P-II family nitrogen regulator -
  L2Y54_RS20965 (L2Y54_20965) - 4241716..4243422 (-) 1707 WP_236498826.1 NAD+ synthase -
  L2Y54_RS21935 - 4243485..4243727 (+) 243 WP_374048252.1 PP0621 family protein -
  L2Y54_RS20970 (L2Y54_20970) - 4243685..4245313 (+) 1629 WP_236498828.1 two-component system sensor histidine kinase NtrB -
  L2Y54_RS20975 (L2Y54_20975) pilR 4245333..4246766 (+) 1434 WP_236498829.1 sigma-54-dependent transcriptional regulator Regulator
  L2Y54_RS20980 (L2Y54_20980) - 4246938..4247147 (+) 210 WP_236498831.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
  L2Y54_RS20985 (L2Y54_20985) - 4247147..4247542 (+) 396 WP_236498832.1 type II toxin-antitoxin system VapC family toxin -
  L2Y54_RS20990 (L2Y54_20990) - 4247597..4248175 (+) 579 WP_236498834.1 Uma2 family endonuclease -
  L2Y54_RS20995 (L2Y54_20995) - 4248172..4248483 (-) 312 WP_236498836.1 BrnA antitoxin family protein -
  L2Y54_RS21005 (L2Y54_21005) - 4248826..4249380 (+) 555 WP_414718481.1 pilin -
  L2Y54_RS21015 (L2Y54_21015) - 4249460..4250005 (+) 546 WP_311196213.1 pilin -
  L2Y54_RS21020 (L2Y54_21020) tfpZ 4250249..4251016 (+) 768 WP_236498838.1 TfpX/TfpZ family type IV pilin accessory protein -
  L2Y54_RS21025 (L2Y54_21025) - 4251319..4251696 (+) 378 WP_236498840.1 MarR family transcriptional regulator -

Sequence

Protein


Download         Length: 477 a.a.        Molecular weight: 52773.52 Da        Isoelectric Point: 6.0362

>NTDB_id=648800 L2Y54_RS20975 WP_236498829.1 4245333..4246766(+) (pilR) [Thiothrix winogradskyi strain CT3]
MTEQTVLIIDDEPDIRELLEITLLRMGLDTITAGDVESALSQIEKYRPHLCLTDMKLPDGSGIDIVRYLQKNHPHIPVAV
ITAFGSMDTAVEALKAGAYDFVSKPVDLPKLRELIQTALKLSAGKGKQPAQTDDDSDTHSNSILGNSPAMQQLKATIHKL
ARSQAPVYIHGESGSGKELVAHQIHQQGSRVKAPFVPVNCGAIPENLMESEFFGHKKGSFTGAMADKQGLFQAAHKGTLF
LDEVADLPLTMQVKLLRAIQEGAVKPVGGLEEIPVDVRILSATHKSLEHEVAAGHFRQDLYYRLNVIKLKVPPLRERQED
ILLLADFFLQKIAERWQMPPIRLSPAARQELGAYGFPGNVRELENVLERASTLCDNNTIQPDDLQLPVAVVTPHPNPAPS
RFGGVPLSGEGLEEKKVMKGEADMLPAWNPVDEEAERDLILRALEQTRWNRTKAAEVLGMSFRQLRYRIQKYGLDEG

Nucleotide


Download         Length: 1434 bp        

>NTDB_id=648800 L2Y54_RS20975 WP_236498829.1 4245333..4246766(+) (pilR) [Thiothrix winogradskyi strain CT3]
ATGACTGAACAAACCGTACTCATCATTGATGATGAACCTGACATTCGTGAACTGTTGGAAATCACCCTGTTACGCATGGG
GCTGGATACCATCACCGCTGGCGACGTGGAGAGCGCTCTCAGCCAGATCGAAAAATACCGCCCGCACCTGTGCCTGACCG
ATATGAAACTACCCGACGGTAGCGGCATCGACATTGTGCGTTACCTGCAAAAAAATCACCCGCACATTCCTGTCGCGGTG
ATTACGGCGTTTGGCAGCATGGATACAGCAGTGGAAGCGCTCAAAGCGGGTGCTTACGATTTCGTGTCCAAACCCGTGGA
TTTGCCAAAACTGCGCGAGTTGATTCAAACCGCCCTGAAGCTTTCCGCTGGTAAAGGCAAACAGCCCGCGCAAACGGATG
ATGATAGCGACACCCACAGCAACAGTATTTTGGGCAATTCCCCGGCGATGCAGCAACTCAAAGCCACCATCCACAAACTG
GCACGTAGCCAAGCGCCGGTTTACATCCACGGTGAATCGGGCAGCGGTAAGGAATTGGTGGCGCACCAGATTCACCAGCA
AGGTTCGCGGGTCAAAGCGCCGTTTGTGCCGGTCAACTGCGGGGCGATTCCTGAAAATCTGATGGAAAGCGAATTCTTTG
GGCACAAAAAAGGCAGCTTTACCGGCGCAATGGCGGATAAGCAGGGGCTGTTTCAAGCGGCGCACAAAGGCACGTTGTTT
TTGGATGAGGTGGCTGATTTGCCGTTGACTATGCAGGTCAAATTGTTGCGGGCGATTCAGGAAGGCGCGGTTAAACCCGT
GGGAGGCTTGGAAGAAATCCCGGTGGATGTGCGGATTCTGAGCGCGACCCACAAGAGTTTAGAACACGAGGTCGCGGCGG
GGCATTTCCGGCAAGATTTGTATTACCGTTTGAATGTGATCAAGTTGAAAGTGCCACCGCTGCGCGAACGGCAGGAGGAT
ATTTTGCTGTTGGCGGACTTTTTCTTGCAGAAAATTGCCGAGCGTTGGCAGATGCCACCGATTCGGTTGTCGCCTGCGGC
GCGGCAAGAGTTGGGGGCGTATGGGTTTCCGGGGAATGTGCGCGAGCTGGAAAACGTGCTGGAGCGGGCGAGTACGTTGT
GTGATAACAATACGATTCAGCCGGATGATTTGCAGTTGCCGGTGGCAGTTGTTACCCCTCACCCCAACCCCGCACCCAGC
CGCTTTGGCGGCGTCCCTCTAAGTGGCGAGGGGCTTGAAGAGAAGAAGGTGATGAAGGGAGAAGCGGACATGTTACCAGC
ATGGAATCCCGTGGATGAGGAGGCGGAACGTGATTTGATTTTGCGGGCGTTGGAACAGACGCGCTGGAATCGGACGAAGG
CAGCAGAAGTATTGGGGATGTCGTTCCGGCAGTTGCGTTACCGGATTCAGAAGTATGGGTTGGATGAGGGTTAA

Domains

Predicted by InterproScan.

Bacterial regulatory protein, Fis family (HTH_8)

(433-472)

Sigma-54 interaction domain (Sigma54_activat)

(143-309)

Response regulator receiver domain (Response_reg)

(6-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

60.211

99.581

0.6
  pilR Acinetobacter baumannii strain A118

49.163

100

0.493