Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG236_RS24950 Genome accession   NZ_CP107910
Coordinates   5452321..5452986 (+) Length   221 a.a.
NCBI ID   WP_266518618.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00453     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5447321..5457986
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG236_RS24930 (OG236_24940) - 5447445..5448626 (+) 1182 WP_328432797.1 acyltransferase -
  OG236_RS24935 (OG236_24945) - 5448667..5450145 (+) 1479 WP_328432798.1 sensor histidine kinase -
  OG236_RS24940 (OG236_24950) vraR 5450142..5450822 (+) 681 WP_266518613.1 response regulator transcription factor Regulator
  OG236_RS24945 (OG236_24955) - 5450957..5452324 (+) 1368 WP_266588832.1 histidine kinase -
  OG236_RS24950 (OG236_24960) vraR 5452321..5452986 (+) 666 WP_266518618.1 response regulator transcription factor Regulator
  OG236_RS24955 (OG236_24965) - 5453056..5454651 (-) 1596 WP_328431880.1 carboxylesterase family protein -
  OG236_RS24960 (OG236_24970) - 5454754..5455392 (-) 639 WP_328431881.1 GPP34 family phosphoprotein -
  OG236_RS24965 (OG236_24975) - 5455555..5456214 (-) 660 WP_328431882.1 response regulator transcription factor -
  OG236_RS24970 (OG236_24980) - 5456211..5457359 (-) 1149 WP_328431883.1 histidine kinase -
  OG236_RS24975 (OG236_24985) - 5457356..5457775 (-) 420 WP_266518628.1 ATP-binding protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23941.68 Da        Isoelectric Point: 4.7252

>NTDB_id=648786 OG236_RS24950 WP_266518618.1 5452321..5452986(+) (vraR) [Streptomyces sp. NBC_00453]
MTIRVLIADDQMMVREGFSVLLNAMPDIEVVGEAVNGREAVDRVRELAPDVVLMDIRMPEMNGIEATREIVAADSPSKVL
VLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVASGEALLAPTVTKRLITEFSKLSTSPRLMQSAQAAYGDLTE
RETEVLVLIAQGLSNAEIAGRLVVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=648786 OG236_RS24950 WP_266518618.1 5452321..5452986(+) (vraR) [Streptomyces sp. NBC_00453]
ATGACCATCCGCGTCCTGATCGCGGACGATCAGATGATGGTGCGCGAGGGCTTCTCGGTCCTGCTGAACGCGATGCCGGA
CATCGAGGTCGTGGGCGAGGCGGTCAACGGCCGCGAGGCGGTCGACCGCGTCCGTGAACTGGCCCCCGACGTGGTCCTGA
TGGACATCCGCATGCCCGAAATGAACGGCATCGAGGCGACCCGGGAGATCGTGGCCGCCGACAGCCCGTCGAAGGTCCTC
GTCCTCACGACCTTCGACCTCGACGAGTACGTGTACCAGGCGCTGCGCGCGGGAGCCTCCGGCTTCCTCCTCAAGGACGC
CTCGGCCCGCCAACTCGCGGACGGCGTAAGGGTGGTGGCCTCCGGTGAGGCACTCCTCGCACCGACCGTCACCAAGCGGC
TGATCACGGAGTTCTCGAAGCTGTCCACGTCCCCCCGCCTCATGCAGTCCGCCCAGGCGGCGTACGGCGATCTGACCGAG
CGTGAGACGGAGGTCCTGGTCCTGATCGCGCAGGGCCTGTCGAACGCGGAGATCGCCGGGCGCCTCGTGGTCGCCGAGTC
GACGATCAAGACCCACGTCAGCCGCATCCTGGTCAAGCTGGGCCTCAGGGACCGCACACAGGCGGCGGTGTTCGCGTACG
AGGCGCGACTGGTGACACCGGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(158-212)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

45.662

99.095

0.452
  degU Bacillus subtilis subsp. subtilis str. 168

42.857

98.19

0.421