Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG236_RS11365 Genome accession   NZ_CP107910
Coordinates   2484318..2484947 (+) Length   209 a.a.
NCBI ID   WP_266512383.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00453     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2479318..2489947
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG236_RS11340 (OG236_11350) - 2479354..2480706 (-) 1353 WP_266512370.1 amidohydrolase -
  OG236_RS11345 (OG236_11355) - 2480844..2481797 (+) 954 WP_328431306.1 endonuclease/exonuclease/phosphatase family protein -
  OG236_RS11350 (OG236_11360) - 2481809..2481997 (-) 189 WP_266512375.1 hypothetical protein -
  OG236_RS11355 (OG236_11365) - 2482123..2482914 (-) 792 WP_266512377.1 class I SAM-dependent methyltransferase -
  OG236_RS11360 (OG236_11370) - 2483080..2484321 (+) 1242 WP_266512380.1 sensor histidine kinase -
  OG236_RS11365 (OG236_11375) vraR 2484318..2484947 (+) 630 WP_266512383.1 response regulator transcription factor Regulator
  OG236_RS11370 (OG236_11380) - 2484953..2486881 (-) 1929 WP_327666823.1 FUSC family protein -
  OG236_RS11375 (OG236_11385) - 2487158..2487952 (-) 795 WP_266512388.1 nucleotidyltransferase domain-containing protein -
  OG236_RS11380 (OG236_11390) - 2488114..2488521 (+) 408 WP_266512391.1 RidA family protein -
  OG236_RS11385 (OG236_11395) - 2488595..2489194 (+) 600 WP_266585461.1 gamma carbonic anhydrase family protein -
  OG236_RS11390 (OG236_11400) - 2489311..2489772 (+) 462 WP_266842207.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 22236.51 Da        Isoelectric Point: 6.7613

>NTDB_id=648766 OG236_RS11365 WP_266512383.1 2484318..2484947(+) (vraR) [Streptomyces sp. NBC_00453]
MSTAPVRLLLCDDHAVVRAGLRALLSSADGIEVVGEAGSGEEALAMAARLHPDVVLMDLQLGEGMDGVTATRRLTTQGDT
HVLVLTMFDTDADITRAIEAGATGYLLKAERPDELFAAIHSAASGRTALSAPVADRLLAQLRSPRPTLSEREHEILGRLA
QGLGNREIARALFISEATVKTHLGRIYGKLGVETRSGAVAVAKERRLLR

Nucleotide


Download         Length: 630 bp        

>NTDB_id=648766 OG236_RS11365 WP_266512383.1 2484318..2484947(+) (vraR) [Streptomyces sp. NBC_00453]
ATGAGTACGGCGCCCGTCCGTCTCCTGCTGTGCGATGACCACGCGGTGGTACGGGCCGGACTGCGCGCGCTGCTGTCGAG
CGCCGACGGCATCGAGGTGGTCGGTGAGGCGGGCAGCGGTGAGGAGGCGCTCGCCATGGCCGCGCGCCTGCACCCCGATG
TCGTACTGATGGACCTCCAGCTCGGCGAGGGCATGGACGGCGTGACGGCGACCAGGCGGCTGACCACTCAAGGAGACACG
CACGTCCTGGTGTTGACCATGTTCGACACGGACGCCGACATCACCCGTGCCATCGAGGCGGGCGCCACGGGATACCTGCT
GAAAGCGGAACGCCCGGACGAGCTGTTCGCGGCGATCCACAGCGCCGCGTCCGGCCGTACGGCCCTGTCGGCACCCGTCG
CCGACCGCCTCCTGGCCCAGCTGCGCAGCCCCCGCCCGACCCTCTCCGAACGCGAACACGAGATCCTCGGCCGGCTGGCC
CAGGGCCTCGGCAACCGGGAGATCGCCCGAGCGCTGTTCATCAGCGAGGCCACGGTGAAGACCCATCTCGGCCGGATCTA
CGGCAAGTTGGGAGTGGAGACGCGGTCGGGCGCGGTGGCGGTGGCGAAGGAGCGGCGGTTGCTGAGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(9-119)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.942

99.522

0.388
  degU Bacillus subtilis subsp. subtilis str. 168

34.862

100

0.364