Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG236_RS10205 Genome accession   NZ_CP107910
Coordinates   2245633..2246274 (-) Length   213 a.a.
NCBI ID   WP_266511785.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00453     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2240633..2251274
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG236_RS10175 (OG236_10180) - 2241082..2241588 (+) 507 WP_266511769.1 HNH endonuclease -
  OG236_RS10180 (OG236_10185) - 2241663..2242619 (-) 957 WP_266511772.1 SPFH domain-containing protein -
  OG236_RS10185 (OG236_10190) - 2242751..2243182 (-) 432 WP_266923615.1 NfeD family protein -
  OG236_RS10190 (OG236_10195) - 2243276..2244073 (-) 798 WP_266511776.1 ABC transporter ATP-binding protein -
  OG236_RS10195 (OG236_10200) - 2244211..2244999 (+) 789 WP_266841242.1 hypothetical protein -
  OG236_RS10200 (OG236_10205) chpE 2245218..2245460 (-) 243 WP_266511782.1 chaplin ChpE -
  OG236_RS10205 (OG236_10210) vraR 2245633..2246274 (-) 642 WP_266511785.1 response regulator transcription factor Regulator
  OG236_RS10210 (OG236_10215) - 2246267..2247412 (-) 1146 WP_266511788.1 GAF domain-containing sensor histidine kinase -
  OG236_RS10215 (OG236_10220) - 2247637..2248335 (+) 699 WP_266511790.1 SDR family NAD(P)-dependent oxidoreductase -
  OG236_RS10220 (OG236_10225) - 2248332..2249417 (+) 1086 WP_328431240.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OG236_RS10225 (OG236_10230) - 2249715..2250488 (+) 774 WP_266511796.1 transglycosylase SLT domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 22839.14 Da        Isoelectric Point: 5.3711

>NTDB_id=648762 OG236_RS10205 WP_266511785.1 2245633..2246274(-) (vraR) [Streptomyces sp. NBC_00453]
MADAIKVLLVDDHQVVRRGLRTFLEVQDDIEVVGEAADGAEGVARAEELKPDVVLMDVKMPGMDGVDALRKLRELANPAR
VLIVTSFTEQRTVVPALRAGAAGYVYKDVDPDALAGAIRSVHAGHILLQPEVAGALLSQEEANSGQGRGGSLTEREREVL
GLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGVTG

Nucleotide


Download         Length: 642 bp        

>NTDB_id=648762 OG236_RS10205 WP_266511785.1 2245633..2246274(-) (vraR) [Streptomyces sp. NBC_00453]
GTGGCTGACGCAATCAAGGTGCTGCTCGTCGACGACCACCAGGTGGTCCGCCGCGGCCTGCGCACGTTCCTCGAAGTGCA
GGACGACATCGAGGTCGTGGGCGAGGCGGCCGACGGCGCCGAAGGAGTGGCGCGTGCCGAGGAGTTGAAGCCCGACGTCG
TCCTGATGGACGTCAAGATGCCCGGCATGGACGGCGTCGACGCGCTCCGCAAGCTCCGCGAGCTGGCGAACCCCGCACGC
GTACTGATCGTGACCAGCTTCACCGAACAGCGCACGGTGGTCCCGGCCCTGCGCGCGGGCGCCGCCGGTTACGTCTACAA
GGACGTCGACCCGGACGCGCTCGCCGGAGCCATCCGCTCGGTCCACGCCGGGCACATCCTGCTCCAACCCGAGGTGGCGG
GCGCCCTGTTGTCCCAGGAGGAGGCCAACTCGGGCCAGGGGAGAGGCGGTTCGCTCACCGAGCGGGAGCGCGAGGTGCTC
GGCCTGATAGCGGACGGCCGCTCGAACCGGGAGATCGCGCGGGCCCTCGTCCTGTCCGAGAAGACCGTGAAGACCCACGT
CTCGAACATCCTGATGAAGCTCGACCTGGCGGACCGCACCCAGGCGGCGCTGTGGGCCGTACGCCACGGCGTGACCGGCT
GA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(151-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

46.445

99.061

0.46
  degU Bacillus subtilis subsp. subtilis str. 168

38.462

100

0.399