Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHU74_RS29290 Genome accession   NZ_CP107907
Coordinates   6406860..6407495 (-) Length   211 a.a.
NCBI ID   WP_371618639.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00454     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6401860..6412495
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHU74_RS29270 (OHU74_29245) aceB 6402096..6403715 (-) 1620 WP_371618635.1 malate synthase A -
  OHU74_RS29275 (OHU74_29250) - 6403988..6404740 (-) 753 WP_371618636.1 NTP transferase domain-containing protein -
  OHU74_RS29280 (OHU74_29255) - 6404966..6406453 (+) 1488 WP_371618637.1 PLP-dependent aminotransferase family protein -
  OHU74_RS29285 (OHU74_29260) - 6406457..6406702 (-) 246 WP_371618638.1 hypothetical protein -
  OHU74_RS29290 (OHU74_29265) vraR 6406860..6407495 (-) 636 WP_371618639.1 response regulator Regulator
  OHU74_RS29295 (OHU74_29270) - 6407495..6408739 (-) 1245 WP_371618640.1 sensor histidine kinase -
  OHU74_RS29300 (OHU74_29275) - 6408874..6409965 (+) 1092 WP_371618641.1 ABC transporter permease -
  OHU74_RS29305 (OHU74_29280) - 6409962..6410645 (+) 684 WP_371618642.1 ABC transporter ATP-binding protein -
  OHU74_RS29310 (OHU74_29285) - 6410763..6411566 (-) 804 WP_371618643.1 IclR family transcriptional regulator -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 22036.37 Da        Isoelectric Point: 5.6583

>NTDB_id=648732 OHU74_RS29290 WP_371618639.1 6406860..6407495(-) (vraR) [Streptomyces sp. NBC_00454]
MTIRLLLADDHPVVRAGLRAVLDTEPDFAVVAEAATAERAVDLAASAGVDVVLMDLQFGPGPGMHGSEATALITARPSAP
RVLVLTTYDTDADILAAVEAGASGYLLKDAPPEELAAAVRTAAAGQSALAPAVALRLMDRMRTPAEALTKRELEVLQLVA
DGLSNQQISKQLFLSQATVKSHLVHIYAKLGVDSRTSAVAAAATRRLIRTP

Nucleotide


Download         Length: 636 bp        

>NTDB_id=648732 OHU74_RS29290 WP_371618639.1 6406860..6407495(-) (vraR) [Streptomyces sp. NBC_00454]
ATGACCATCCGGCTGCTGCTCGCCGACGACCACCCGGTGGTCCGGGCCGGGCTGCGCGCGGTGCTGGACACCGAGCCGGA
CTTCGCGGTGGTGGCGGAGGCCGCGACGGCGGAGCGCGCGGTGGACCTGGCGGCCTCCGCGGGGGTGGACGTGGTCCTGA
TGGACCTCCAGTTCGGCCCCGGGCCCGGTATGCACGGCTCGGAGGCCACGGCCCTGATCACGGCCCGGCCCTCGGCCCCC
AGGGTGCTGGTCCTGACCACGTACGACACGGACGCGGACATCCTGGCCGCGGTGGAGGCGGGCGCCTCGGGCTACCTGCT
CAAGGACGCCCCGCCGGAGGAACTCGCGGCGGCCGTGCGCACCGCGGCGGCCGGCCAGTCGGCCCTGGCCCCGGCGGTGG
CCCTGCGCCTGATGGACCGCATGCGGACCCCCGCCGAAGCCCTGACCAAGCGCGAGCTGGAGGTCCTCCAGCTGGTCGCG
GACGGCCTGTCGAACCAGCAGATCTCCAAACAGCTCTTCCTGAGCCAGGCCACGGTCAAATCCCACCTGGTCCACATCTA
CGCCAAACTCGGCGTCGACTCCCGCACCTCGGCAGTGGCCGCAGCCGCCACCCGCCGCCTGATCCGCACGCCGTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-119)

Bacterial regulatory proteins, luxR family (GerE)

(147-201)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.208

100

0.384
  degU Bacillus subtilis subsp. subtilis str. 168

35

100

0.365