Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHU74_RS26290 Genome accession   NZ_CP107907
Coordinates   5662281..5662982 (-) Length   233 a.a.
NCBI ID   WP_371618137.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00454     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5657281..5667982
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHU74_RS26270 (OHU74_26260) - 5657580..5659019 (+) 1440 WP_371618134.1 gamma-aminobutyraldehyde dehydrogenase -
  OHU74_RS26275 (OHU74_26265) - 5659185..5660363 (+) 1179 WP_371619817.1 spermidine/putrescine ABC transporter substrate-binding protein -
  OHU74_RS26280 (OHU74_26270) - 5660451..5660915 (+) 465 WP_371618135.1 hypothetical protein -
  OHU74_RS26285 (OHU74_26275) - 5660919..5662133 (-) 1215 WP_371618136.1 serine hydrolase domain-containing protein -
  OHU74_RS26290 (OHU74_26280) vraR 5662281..5662982 (-) 702 WP_371618137.1 response regulator Regulator
  OHU74_RS26295 (OHU74_26285) - 5662979..5664187 (-) 1209 WP_371619818.1 sensor histidine kinase -
  OHU74_RS26300 (OHU74_26290) - 5664187..5664876 (-) 690 WP_371618138.1 glycerophosphodiester phosphodiesterase -
  OHU74_RS26305 (OHU74_26295) - 5664898..5665923 (-) 1026 WP_371618139.1 adenosine deaminase -
  OHU74_RS26310 (OHU74_26300) - 5666032..5666760 (+) 729 WP_371618140.1 DUF4190 domain-containing protein -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 24493.91 Da        Isoelectric Point: 4.4606

>NTDB_id=648724 OHU74_RS26290 WP_371618137.1 5662281..5662982(-) (vraR) [Streptomyces sp. NBC_00454]
MTIRVVVADDQELVRSGFAMILDVQEDIEVVAEVGDGAAAVAAVRDLAPDVALLDIRMPVLDGIEACRTISASSSCRTVM
LTTFDSDEYVYEALHAGASGFLLKDVRRDDLVHAVRVVAAGDSLLAPSVARRLIEEYTAATARPAAGEVLSAERLEALTA
RERETLLLLGRGLSNAEIAGALTVSEHTVKSHVGNVLSKLGLRDRIQAVICAYETGLIAAGGPAGSWVSPSGE

Nucleotide


Download         Length: 702 bp        

>NTDB_id=648724 OHU74_RS26290 WP_371618137.1 5662281..5662982(-) (vraR) [Streptomyces sp. NBC_00454]
GTGACGATCCGTGTGGTGGTGGCCGACGATCAGGAGCTGGTGCGCAGCGGCTTCGCGATGATCCTGGACGTCCAGGAGGA
CATCGAGGTCGTGGCGGAGGTCGGGGACGGTGCGGCGGCGGTGGCCGCGGTGCGGGACCTGGCGCCGGACGTGGCGCTGC
TGGACATCCGGATGCCGGTGCTGGACGGCATCGAGGCGTGCCGGACGATCTCGGCGAGCAGCTCCTGCCGGACGGTGATG
CTGACGACCTTCGACTCGGACGAGTACGTGTACGAGGCGCTGCACGCGGGGGCCAGCGGGTTCCTGCTCAAGGACGTGCG
GCGGGACGATCTGGTGCACGCGGTACGGGTGGTGGCCGCGGGCGATTCCCTGCTGGCGCCTTCGGTGGCCCGGCGCCTGA
TCGAGGAGTACACGGCGGCCACCGCCCGGCCGGCGGCCGGGGAGGTCCTGTCGGCCGAGCGGCTGGAGGCGCTGACGGCC
CGCGAGCGGGAGACGCTGCTGCTCCTGGGGCGGGGGCTGTCGAACGCGGAGATCGCGGGGGCGCTGACCGTGAGCGAGCA
CACGGTCAAATCGCATGTGGGCAACGTGTTGTCGAAGCTGGGGCTGCGGGACCGGATCCAGGCGGTGATCTGCGCGTACG
AGACGGGTTTGATCGCGGCCGGCGGGCCGGCTGGCTCTTGGGTATCTCCCTCTGGGGAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(157-212)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

42.009

93.991

0.395
  degU Bacillus subtilis subsp. subtilis str. 168

39.462

95.708

0.378