Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHN74_RS32540 Genome accession   NZ_CP107903
Coordinates   7350955..7351638 (+) Length   227 a.a.
NCBI ID   WP_327698126.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00459     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7345955..7356638
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHN74_RS32520 (OHN74_32510) - 7346239..7346469 (-) 231 WP_055532400.1 hypothetical protein -
  OHN74_RS32525 (OHN74_32515) - 7346921..7349041 (+) 2121 WP_327698123.1 DNA topoisomerase IV subunit B -
  OHN74_RS32530 (OHN74_32520) - 7349247..7349810 (+) 564 WP_327698124.1 DUF1453 domain-containing protein -
  OHN74_RS32535 (OHN74_32525) - 7349807..7350958 (+) 1152 WP_327698125.1 histidine kinase -
  OHN74_RS32540 (OHN74_32530) vraR 7350955..7351638 (+) 684 WP_327698126.1 response regulator transcription factor Regulator
  OHN74_RS32545 (OHN74_32535) - 7351708..7352274 (+) 567 WP_327698127.1 DUF485 domain-containing protein -
  OHN74_RS32550 (OHN74_32540) - 7352271..7353863 (+) 1593 WP_327698128.1 cation acetate symporter -
  OHN74_RS32555 (OHN74_32545) - 7353922..7354614 (-) 693 WP_327698129.1 response regulator -
  OHN74_RS32560 (OHN74_32550) - 7354828..7355508 (-) 681 WP_327698130.1 response regulator -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 24273.79 Da        Isoelectric Point: 5.7330

>NTDB_id=648536 OHN74_RS32540 WP_327698126.1 7350955..7351638(+) (vraR) [Streptomyces sp. NBC_00459]
MTREAGPKLARVVVADDQTVVREGIVMLLGLLPGIEVVGAAGDGDEAVRLAGELAPDVVLMDLRMPRCDGVEATRRIRAE
YPGTQVVVLTTFADDESLFRALKAGARGYLTKDADGDEIVRAVHSVLSGDAGLAPSIQRRLLERLTEPEKKPAAPAEPPD
GLTTRETEVLVLIADGLSNQEIAHQLHVSTATVKTHINNLFAKTGIKDRAQAVRYAYGRGLVRPPTG

Nucleotide


Download         Length: 684 bp        

>NTDB_id=648536 OHN74_RS32540 WP_327698126.1 7350955..7351638(+) (vraR) [Streptomyces sp. NBC_00459]
ATGACGCGGGAGGCCGGCCCGAAGCTCGCGCGGGTCGTGGTCGCGGACGACCAGACCGTCGTACGGGAAGGCATCGTGAT
GCTGCTCGGGCTGCTGCCCGGCATCGAGGTCGTCGGAGCGGCCGGAGACGGGGACGAGGCCGTGAGGCTCGCCGGTGAAC
TCGCGCCGGACGTGGTGCTGATGGATCTGCGCATGCCGCGCTGCGACGGTGTCGAGGCGACCCGGCGGATCAGGGCGGAG
TACCCCGGGACGCAGGTCGTGGTGCTCACGACGTTCGCGGACGACGAGTCGCTGTTCCGTGCGCTGAAGGCGGGCGCGCG
CGGCTATCTCACCAAGGATGCGGACGGTGACGAGATCGTCCGGGCGGTGCACAGCGTGCTGTCCGGGGACGCGGGGCTGG
CGCCGAGCATCCAGCGGCGGCTCCTGGAGCGGCTGACGGAGCCGGAGAAGAAGCCTGCCGCGCCCGCCGAGCCGCCCGAC
GGGCTCACCACGAGGGAGACCGAGGTGCTGGTGCTGATCGCGGACGGCCTCAGCAACCAGGAGATCGCGCACCAACTGCA
TGTCTCCACAGCGACCGTGAAGACCCACATCAACAACCTCTTCGCCAAGACGGGAATCAAGGACCGTGCGCAGGCGGTGC
GTTACGCCTACGGGAGGGGGTTGGTGCGGCCTCCCACGGGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(161-216)

Response regulator receiver domain (Response_reg)

(12-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.376

93.833

0.379
  degU Bacillus subtilis subsp. subtilis str. 168

38.288

97.797

0.374