Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHN74_RS08755 Genome accession   NZ_CP107903
Coordinates   2022255..2022896 (-) Length   213 a.a.
NCBI ID   WP_327693951.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00459     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2017255..2027896
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHN74_RS08725 (OHN74_08740) - 2017709..2018215 (+) 507 WP_327693945.1 HNH endonuclease -
  OHN74_RS08730 (OHN74_08745) - 2018304..2019257 (-) 954 WP_327693946.1 SPFH domain-containing protein -
  OHN74_RS08735 (OHN74_08750) - 2019406..2019837 (-) 432 WP_327693947.1 NfeD family protein -
  OHN74_RS08740 (OHN74_08755) - 2019947..2020738 (-) 792 WP_327693948.1 ABC transporter ATP-binding protein -
  OHN74_RS08745 (OHN74_08760) - 2020862..2021644 (+) 783 WP_327693949.1 hypothetical protein -
  OHN74_RS08750 (OHN74_08765) chpE 2021862..2022107 (-) 246 WP_327693950.1 chaplin ChpE -
  OHN74_RS08755 (OHN74_08770) vraR 2022255..2022896 (-) 642 WP_327693951.1 response regulator transcription factor Regulator
  OHN74_RS08760 (OHN74_08775) - 2022889..2024034 (-) 1146 WP_327693952.1 GAF domain-containing sensor histidine kinase -
  OHN74_RS08765 (OHN74_08780) - 2024220..2024915 (+) 696 WP_327693953.1 SDR family NAD(P)-dependent oxidoreductase -
  OHN74_RS08770 (OHN74_08785) - 2024912..2025958 (+) 1047 WP_327693954.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OHN74_RS08775 (OHN74_08790) - 2026300..2027022 (+) 723 WP_327693955.1 transglycosylase SLT domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23139.41 Da        Isoelectric Point: 5.3618

>NTDB_id=648478 OHN74_RS08755 WP_327693951.1 2022255..2022896(-) (vraR) [Streptomyces sp. NBC_00459]
MADAIKVLLVDDHQVVRRGLRTFLEVQDDIEVVGEASDGAEGVDRAQELKPDVVLMDIKMPGMDGVEALRRLRELDNPAR
VLIVTSFTEQRTVVPALRAGAAGYVYKDIDPDALAGAIRSVHAGHILLQPEVAGALLSQEETHSGQGRSGSLTEREREVL
TLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGVTG

Nucleotide


Download         Length: 642 bp        

>NTDB_id=648478 OHN74_RS08755 WP_327693951.1 2022255..2022896(-) (vraR) [Streptomyces sp. NBC_00459]
GTGGCTGACGCGATCAAGGTGCTGCTCGTCGACGACCACCAGGTGGTCCGCCGGGGCCTGCGCACGTTCCTCGAAGTGCA
GGACGACATCGAGGTCGTGGGCGAGGCGTCGGACGGCGCCGAGGGAGTCGACCGCGCGCAGGAACTGAAACCCGACGTCG
TCCTCATGGACATCAAGATGCCGGGCATGGACGGCGTCGAGGCGTTGCGCAGACTCCGCGAACTCGACAACCCCGCGCGC
GTGCTGATCGTCACGAGCTTCACCGAGCAGCGCACGGTGGTCCCCGCACTGCGCGCGGGCGCCGCCGGCTACGTCTACAA
GGACATCGACCCGGACGCCCTCGCCGGCGCGATCCGCTCCGTGCACGCCGGACACATCCTGCTCCAGCCCGAGGTCGCGG
GCGCACTGCTGAGCCAGGAGGAGACGCACTCGGGCCAGGGGAGGAGCGGCTCGCTCACCGAGCGGGAGCGCGAGGTACTG
ACCCTGATCGCGGACGGCCGCTCGAACCGGGAGATAGCCCGCGCCCTGGTGCTGTCCGAGAAGACGGTCAAGACGCATGT
CTCGAACATCCTGATGAAACTCGACCTGGCGGACCGCACGCAGGCGGCGTTGTGGGCGGTACGTCACGGTGTGACCGGAT
GA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(151-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

46.411

98.122

0.455
  degU Bacillus subtilis subsp. subtilis str. 168

39.367

100

0.408