Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG912_RS05950 Genome accession   NZ_CP107899
Coordinates   1386706..1387383 (-) Length   225 a.a.
NCBI ID   WP_327708497.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00464     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1381706..1392383
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG912_RS05925 (OG912_05925) - 1382971..1383651 (+) 681 WP_327708493.1 response regulator -
  OG912_RS05930 (OG912_05930) - 1383661..1384044 (-) 384 WP_327708494.1 helix-turn-helix domain-containing protein -
  OG912_RS05935 (OG912_05935) - 1384152..1384514 (+) 363 WP_327713349.1 DoxX family protein -
  OG912_RS05940 (OG912_05940) - 1384542..1386134 (-) 1593 WP_327708495.1 cation acetate symporter -
  OG912_RS05945 (OG912_05945) - 1386131..1386607 (-) 477 WP_327708496.1 DUF485 domain-containing protein -
  OG912_RS05950 (OG912_05950) vraR 1386706..1387383 (-) 678 WP_327708497.1 response regulator transcription factor Regulator
  OG912_RS05955 (OG912_05955) - 1387380..1388543 (-) 1164 WP_327708498.1 histidine kinase -
  OG912_RS05960 (OG912_05960) - 1388540..1389058 (-) 519 WP_327708499.1 DUF1453 domain-containing protein -
  OG912_RS05965 (OG912_05965) - 1389274..1391394 (-) 2121 WP_327708500.1 DNA topoisomerase IV subunit B -
  OG912_RS05970 (OG912_05970) - 1391828..1392061 (+) 234 WP_024489001.1 hypothetical protein -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 23799.14 Da        Isoelectric Point: 4.9371

>NTDB_id=648313 OG912_RS05950 WP_327708497.1 1386706..1387383(-) (vraR) [Streptomyces sp. NBC_00464]
MSARVVVADDQSVVREGIVMLLGLLPGIEVVASAKDGEEAVALVAEHAPDVVLMDLRMPRCDGVEATRRIRRDFPGTQVV
VLTTFDDDDSLFPALRAGARGYLTKDAGGDEIVRAIQAVLSGEAGLSPTIQRRLLEQVTTGPQPSAGGAEAGLPDGMTSR
EAEVLVLIAEGMSNAEIARSLHISQATVKSHINNLFAKAGLRDRAQAVRYAYVRGLAQPPGTSFT

Nucleotide


Download         Length: 678 bp        

>NTDB_id=648313 OG912_RS05950 WP_327708497.1 1386706..1387383(-) (vraR) [Streptomyces sp. NBC_00464]
GTGAGCGCGCGGGTGGTGGTCGCCGACGATCAGTCGGTGGTGCGTGAGGGAATCGTCATGCTCCTGGGCCTGCTGCCCGG
GATCGAGGTGGTCGCCTCGGCGAAGGACGGGGAGGAGGCTGTCGCCCTTGTGGCCGAACACGCCCCGGACGTCGTCCTGA
TGGACCTGAGAATGCCCCGCTGCGACGGCGTGGAGGCGACGCGCCGTATCCGCAGGGACTTTCCCGGTACCCAGGTCGTG
GTGCTGACGACCTTCGACGACGACGATTCGCTCTTCCCCGCGCTCCGGGCGGGGGCCCGCGGCTACCTCACCAAGGACGC
CGGGGGCGACGAGATCGTGCGGGCCATTCAGGCGGTGCTCTCGGGCGAGGCGGGTCTCTCGCCCACCATCCAGCGCCGTC
TGCTGGAGCAGGTCACCACGGGGCCCCAGCCGTCCGCCGGCGGCGCTGAGGCCGGGCTGCCCGACGGGATGACGTCTCGT
GAGGCCGAGGTGCTCGTGCTGATCGCCGAAGGGATGTCCAACGCGGAGATCGCTCGGAGCCTGCATATTTCGCAGGCCAC
GGTGAAGAGCCATATCAACAACCTGTTCGCCAAGGCGGGGCTTCGCGACCGGGCCCAGGCGGTTCGCTATGCGTACGTTC
GAGGACTCGCACAGCCGCCCGGGACATCCTTCACCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(157-211)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.073

96.889

0.369
  degU Bacillus subtilis subsp. subtilis str. 168

36.444

100

0.364