Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG210_RS04310 Genome accession   NZ_CP107896
Coordinates   993383..994057 (-) Length   224 a.a.
NCBI ID   WP_328332290.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00466 strain NBC 00466     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 988383..999057
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG210_RS04285 (OG210_04290) - 988630..989529 (-) 900 WP_328332298.1 ABC transporter permease -
  OG210_RS04290 (OG210_04295) - 989519..990334 (-) 816 WP_328332296.1 ABC transporter ATP-binding protein -
  OG210_RS04295 (OG210_04300) - 990491..991213 (+) 723 WP_371535024.1 response regulator -
  OG210_RS04300 (OG210_04305) - 991187..992779 (-) 1593 WP_328335638.1 cation acetate symporter -
  OG210_RS04305 (OG210_04310) - 992791..993261 (-) 471 WP_328332292.1 DUF485 domain-containing protein -
  OG210_RS04310 (OG210_04315) vraR 993383..994057 (-) 675 WP_328332290.1 response regulator transcription factor Regulator
  OG210_RS04315 (OG210_04320) - 994054..995199 (-) 1146 WP_328332288.1 histidine kinase -
  OG210_RS04320 (OG210_04325) - 995196..995717 (-) 522 WP_328332286.1 DUF1453 domain-containing protein -
  OG210_RS04325 (OG210_04330) - 995903..998023 (-) 2121 WP_328332284.1 DNA topoisomerase IV subunit B -
  OG210_RS04330 (OG210_04335) - 998457..998687 (+) 231 WP_266852304.1 hypothetical protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 23825.37 Da        Isoelectric Point: 5.1017

>NTDB_id=648244 OG210_RS04310 WP_328332290.1 993383..994057(-) (vraR) [Streptomyces sp. NBC_00466 strain NBC 00466]
MTARVVVADDQSVVREGIVMLLGLLPGVEVVGAARDGVEAVALVGEHAPDVVLMDLRMPRCDGVEATRRIREQYPSTQVV
VLTTFSDDDSLFPALQAGARGYLTKDAGGEEIVRAIEDVMAGQAGLSPSVQRLLVERVTAPPAPAPRTAVELPDGLTPRE
AEILALIAEGLSNSEISRSLHISPATVKTHINNLFAKTGIRDRAQAVRYAYRHGLALPPGIPLT

Nucleotide


Download         Length: 675 bp        

>NTDB_id=648244 OG210_RS04310 WP_328332290.1 993383..994057(-) (vraR) [Streptomyces sp. NBC_00466 strain NBC 00466]
ATGACGGCACGGGTGGTGGTGGCCGACGATCAGTCCGTCGTGCGTGAAGGCATCGTGATGCTGCTGGGGCTGCTGCCCGG
GGTCGAGGTCGTGGGAGCGGCCAGGGACGGAGTGGAGGCCGTCGCCCTCGTAGGTGAACACGCCCCCGACGTGGTCCTGA
TGGATCTGCGGATGCCCCGTTGCGACGGGGTGGAGGCGACCCGTCGTATCCGCGAGCAGTATCCGTCCACTCAGGTCGTG
GTGCTCACGACGTTCTCCGACGACGACTCGCTCTTTCCCGCGCTGCAGGCCGGGGCGCGCGGGTACCTCACCAAGGACGC
CGGTGGCGAGGAGATCGTCCGGGCCATCGAGGACGTCATGGCCGGACAGGCCGGGCTCTCGCCGAGCGTGCAGCGGCTGC
TCGTCGAGCGGGTCACCGCGCCGCCCGCGCCGGCCCCGCGGACCGCAGTGGAGCTGCCCGACGGCCTCACCCCCCGGGAG
GCCGAGATCCTGGCCCTTATCGCGGAAGGGCTCTCCAATTCGGAGATCTCCCGCTCGCTGCACATCTCGCCGGCCACCGT
GAAGACGCACATCAACAATCTCTTCGCCAAGACCGGGATACGGGACCGGGCGCAGGCCGTGCGCTATGCCTACCGGCACG
GTCTTGCCCTGCCGCCGGGCATACCCCTCACCTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(155-210)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40

95.982

0.384
  degU Bacillus subtilis subsp. subtilis str. 168

38.009

98.661

0.375