Detailed information NTG0648184

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OG803_RS15350
• Genome accession: NZ_CP107894
• Coordinates: 3350918..3352042 (+)
• Length: 374 a.a.
• NCBI ID: WP_313944917.1
• Uniprot ID: A0ACC6PYI5
• Organism: Streptomyces sp. NBC_00467
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3345918..3357042

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OG803_RS15340 (OG803_15350)	-	3347505..3349184 (-)	1680	WP_327681647.1	hypothetical protein	-
OG803_RS15345 (OG803_15355)	radA/sms	3349419..3350873 (+)	1455	WP_327681649.1	DNA repair protein RadA	Machinery gene
OG803_RS15350 (OG803_15360)	disA	3350918..3352042 (+)	1125	WP_313944917.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OG803_RS15355 (OG803_15365)	-	3352150..3352968 (-)	819	WP_327681651.1	hypothetical protein	-
OG803_RS15360 (OG803_15370)	-	3353583..3354488 (+)	906	WP_327681653.1	A/G-specific adenine glycosylase	-
OG803_RS15365 (OG803_15375)	-	3354673..3355278 (+)	606	WP_327681655.1	SigE family RNA polymerase sigma factor	-
OG803_RS15370 (OG803_15380)	-	3355266..3355937 (+)	672	WP_313944921.1	hypothetical protein	-
OG803_RS15375 (OG803_15385)	cseB	3355947..3356654 (+)	708	WP_327681658.1	two-component system response regulator CseB	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40387.25 Da
• Isoelectric Point: 4.8731

>NTDB_id=648184 OG803_RS15350 WP_313944917.1 3350918..3352042(+) (disA) [Streptomyces sp. NBC_00467]
MAANDRAAAPGKSGGGSGNEALIRAALSAVAPGQALRDGLERILRGNTGGLIVLGMDKTVESMCTGGFVLDVEFTATRLR
ELCKLDGALILDKDITKILRAGVQLVPDASIPTEETGTRHRTADRVSRQCGFPVVSVSQSMRLIALYVDGERRVLEESAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALFELDSLTHTELLELPIVARALGYSGSPETLDSAVSPRGYRLLAKVPRLPGA
IIERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=648184 OG803_RS15350 WP_313944917.1 3350918..3352042(+) (disA) [Streptomyces sp. NBC_00467]
GTGGCAGCCAACGACCGGGCAGCAGCACCCGGAAAGTCCGGCGGAGGCTCCGGCAACGAAGCACTGATCCGCGCCGCCCT
GAGCGCGGTGGCGCCGGGCCAGGCCCTGCGCGACGGCCTGGAGCGGATCCTCCGCGGCAACACCGGCGGCCTGATCGTCC
TCGGCATGGACAAAACGGTCGAATCGATGTGCACCGGCGGCTTCGTGCTGGATGTCGAGTTCACCGCGACCCGGCTGCGC
GAGCTGTGCAAGCTGGACGGCGCGCTGATCCTCGACAAGGACATCACCAAGATCCTCCGGGCCGGTGTGCAGCTGGTCCC
GGACGCGTCCATCCCCACCGAGGAGACCGGCACCCGCCACCGCACGGCGGACCGGGTGTCGCGTCAGTGCGGCTTCCCCG
TCGTGTCCGTGTCGCAGTCCATGCGCCTCATCGCGCTGTACGTGGACGGGGAGCGCCGGGTCCTGGAGGAGTCGGCCGCG
ATCCTGTCCCGCGCGAACCAGGCCCTCGCGACCCTGGAGCGCTACAAGCTCCGCCTCGACGAGGTCGCGGGCACGCTCTC
CGCGCTGGAGATCGAGGACCTGGTGACGGTCCGGGACGTCACGGCCGTGGCCCAGCGCCTGGAGATGGTGCGACGGATCG
CCACCGAGATCGCCGAGTACGTGGTCGAGTTGGGCACCGACGGACGGCTGCTCTCCCTCCAGCTCGACGAGTTGATCGCG
GGCGTCGAGCCCGAGCGCGAGCTGGTGGTGCGTGACTATGTGCCCGAGCCCACCGCGAAGCGGTCCCGTACCGTCGACGA
GGCCCTGTTCGAGCTGGACTCCCTGACCCACACGGAACTACTGGAACTACCCATAGTGGCCAGGGCGCTCGGCTACAGCG
GCTCGCCCGAGACCCTCGACTCCGCGGTCTCCCCGCGCGGCTACCGGCTGCTGGCGAAGGTACCGAGGCTGCCGGGCGCG
ATCATCGAGCGACTGGTGGAGCACTTCGGCGGGCTACAGAAGCTGCTCGCGGCGAGCGTCGACGACCTTCAGACGGTCGA
CGGTGTGGGCGAGGCGCGCGCACGCAGCGTCCGCGAGGGCCTGTCGCGGCTTGCGGAGTCCTCGATCCTCGAGCGGTACG
TCTAG

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.429	96.524	0.438