Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG889_RS43135 Genome accession   NZ_CP107882
Coordinates   9883555..9884193 (+) Length   212 a.a.
NCBI ID   WP_326585966.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00481     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 9878555..9889193
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG889_RS43120 (OG889_43210) - 9879185..9879878 (+) 694 Protein_8531 GntR family transcriptional regulator -
  OG889_RS43125 (OG889_43215) - 9879893..9881533 (-) 1641 WP_326585137.1 AMP-binding protein -
  OG889_RS43130 (OG889_43220) - 9881903..9883558 (+) 1656 WP_326585138.1 GAF domain-containing sensor histidine kinase -
  OG889_RS43135 (OG889_43225) vraR 9883555..9884193 (+) 639 WP_326585966.1 response regulator transcription factor Regulator
  OG889_RS43140 (OG889_43230) - 9884337..9885248 (+) 912 WP_326585139.1 SDR family oxidoreductase -
  OG889_RS43145 - 9885303..9885536 (-) 234 WP_326585140.1 IclR family transcriptional regulator C-terminal domain-containing protein -
  OG889_RS43150 - 9885594..9885803 (-) 210 WP_326585141.1 IclR family transcriptional regulator C-terminal domain-containing protein -
  OG889_RS43155 (OG889_43240) - 9885963..9886421 (+) 459 WP_326585142.1 aldehyde dehydrogenase family protein -
  OG889_RS43160 (OG889_43245) - 9886312..9886539 (+) 228 WP_326585967.1 aldehyde dehydrogenase family protein -
  OG889_RS43165 (OG889_43250) - 9886509..9887453 (-) 945 WP_326585143.1 superoxide dismutase -

Sequence

Protein


Download         Length: 212 a.a.        Molecular weight: 22701.25 Da        Isoelectric Point: 6.3476

>NTDB_id=648048 OG889_RS43135 WP_326585966.1 9883555..9884193(+) (vraR) [Streptomyces sp. NBC_00481]
MIVDDHAVVRRGIRAYLEVLDDMEVAAEAADGQEALTRLDAMAAHRELPDVVLIDLLMPKMDGVTAIGAIKQRHPGLRLV
VLTSFGEMERVHAALAQGAAGYLLKDAEAGEVVAAIRAAARGEVFLDPAVARGLTQEIVSPPTGLASLTSRERDVLVLVA
EGRSNQQIADELVISERTARTHVSNVLRKLRLTSRTQAALLAVRQGLVPPKG

Nucleotide


Download         Length: 639 bp        

>NTDB_id=648048 OG889_RS43135 WP_326585966.1 9883555..9884193(+) (vraR) [Streptomyces sp. NBC_00481]
CTGATCGTCGACGACCACGCCGTCGTACGCCGCGGAATCCGTGCCTACCTCGAGGTCCTGGACGACATGGAAGTGGCCGC
GGAGGCCGCCGACGGCCAGGAGGCACTCACCCGGCTCGACGCGATGGCCGCCCACCGGGAACTGCCGGACGTGGTCTTGA
TTGACCTGCTCATGCCCAAGATGGACGGGGTGACCGCGATCGGAGCGATCAAGCAGCGCCACCCCGGTCTCCGACTCGTG
GTGCTCACCAGCTTCGGAGAGATGGAACGCGTCCACGCGGCACTCGCCCAGGGAGCCGCCGGCTACCTGCTCAAGGACGC
CGAAGCGGGCGAAGTGGTCGCCGCGATCCGCGCGGCCGCCCGGGGCGAGGTCTTCCTCGACCCCGCGGTGGCCAGGGGAC
TCACCCAGGAGATCGTTTCGCCGCCGACCGGGCTCGCCTCTCTCACCAGCCGGGAACGCGACGTCCTCGTCCTCGTCGCC
GAGGGACGGTCGAACCAGCAGATCGCCGACGAGTTGGTGATCAGCGAGCGCACCGCCCGCACCCACGTGAGCAACGTCCT
GCGCAAACTCCGGCTCACCTCCCGGACCCAGGCCGCGTTGCTCGCGGTGCGGCAAGGACTGGTGCCTCCGAAGGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(1-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.385

98.113

0.396
  degU Bacillus subtilis subsp. subtilis str. 168

35.111

100

0.373