Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA73_RS15290 Genome accession   NZ_CP107880
Coordinates   3452193..3452870 (+) Length   225 a.a.
NCBI ID   WP_266720021.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00483     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3447193..3457870
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA73_RS15270 (OHA73_15280) - 3447794..3448435 (+) 642 WP_327655305.1 TetR family transcriptional regulator -
  OHA73_RS15275 (OHA73_15285) - 3448553..3449764 (+) 1212 WP_266720027.1 alpha/beta hydrolase -
  OHA73_RS15280 (OHA73_15290) - 3449841..3450719 (+) 879 WP_267070584.1 DUF4429 domain-containing protein -
  OHA73_RS15285 (OHA73_15295) - 3450801..3452177 (+) 1377 WP_327655306.1 sensor histidine kinase -
  OHA73_RS15290 (OHA73_15300) vraR 3452193..3452870 (+) 678 WP_266720021.1 response regulator transcription factor Regulator
  OHA73_RS15295 (OHA73_15305) - 3453024..3454154 (+) 1131 WP_327655307.1 alpha/beta hydrolase -
  OHA73_RS15300 (OHA73_15310) - 3454151..3455380 (+) 1230 WP_327655308.1 acyltransferase -
  OHA73_RS15305 (OHA73_15315) - 3455423..3456469 (-) 1047 WP_327655309.1 aldo/keto reductase -
  OHA73_RS15310 (OHA73_15320) - 3456475..3456948 (-) 474 WP_266720014.1 MerR family transcriptional regulator -
  OHA73_RS15315 (OHA73_15325) - 3457061..3457528 (+) 468 WP_266720012.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 24234.14 Da        Isoelectric Point: 6.4996

>NTDB_id=647898 OHA73_RS15290 WP_266720021.1 3452193..3452870(+) (vraR) [Streptomyces sp. NBC_00483]
MTIRVIIVDDQTMVRAGFAALLNAQSDIDVVGEAPDGKEGVQVSRSTHPDVVLMDVRMPEMDGLAATKELMDPPPGVVHR
PKVLMLTTFDVDDYVYAALRAGASGFLLKDAPPADLISAVRVIAAGEALLAPTVTKRLIADFAKTRPANRKSHDPLLKTL
TPRESEVLELIARGLSNQEIAQKLVLAEQTVKTHIGRVLAKLGLRDRAQAVIFAYESGLVEPGGR

Nucleotide


Download         Length: 678 bp        

>NTDB_id=647898 OHA73_RS15290 WP_266720021.1 3452193..3452870(+) (vraR) [Streptomyces sp. NBC_00483]
ATGACCATTCGCGTGATCATCGTCGACGACCAGACCATGGTGCGGGCGGGTTTCGCCGCGCTGTTGAACGCACAGAGCGA
CATCGACGTCGTGGGAGAGGCCCCGGACGGCAAGGAAGGCGTCCAGGTGAGCCGCTCCACGCATCCCGATGTCGTCCTCA
TGGATGTCCGGATGCCCGAGATGGACGGGCTGGCCGCAACGAAGGAACTGATGGACCCGCCGCCCGGCGTGGTGCACCGG
CCGAAGGTCCTGATGCTCACCACGTTCGACGTCGACGACTATGTGTACGCCGCACTGCGGGCGGGCGCGTCCGGGTTTCT
GCTCAAGGACGCGCCACCGGCCGATCTGATCTCCGCGGTGCGCGTGATCGCGGCCGGTGAGGCACTGCTCGCTCCCACGG
TCACCAAGCGCCTCATCGCGGACTTCGCCAAGACCCGCCCCGCAAACCGCAAGAGCCACGATCCGCTCCTGAAGACCCTG
ACCCCGCGTGAGTCCGAGGTTCTCGAGCTGATCGCGCGCGGACTGTCCAACCAGGAGATCGCGCAGAAGCTGGTGCTGGC
CGAGCAGACGGTGAAGACCCATATCGGCCGTGTGCTGGCGAAGTTGGGCCTGCGCGACCGGGCGCAGGCCGTGATCTTCG
CGTATGAATCGGGTCTTGTAGAGCCCGGCGGACGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-121)

Bacterial regulatory proteins, luxR family (GerE)

(159-214)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

43.694

98.667

0.431
  degU Bacillus subtilis subsp. subtilis str. 168

37.281

100

0.378