Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA73_RS12095 Genome accession   NZ_CP107880
Coordinates   2755929..2756570 (-) Length   213 a.a.
NCBI ID   WP_267070926.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00483     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2750929..2761570
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA73_RS12060 (OHA73_12075) - 2751016..2751522 (+) 507 WP_266721151.1 HNH endonuclease -
  OHA73_RS12065 (OHA73_12080) - 2751583..2752542 (-) 960 WP_266721150.1 SPFH domain-containing protein -
  OHA73_RS12070 (OHA73_12085) - 2752679..2753113 (-) 435 WP_266721149.1 NfeD family protein -
  OHA73_RS12075 (OHA73_12090) - 2753182..2753979 (-) 798 WP_266721148.1 ABC transporter ATP-binding protein -
  OHA73_RS12080 (OHA73_12095) - 2754145..2754927 (+) 783 WP_327655038.1 hypothetical protein -
  OHA73_RS12085 (OHA73_12100) - 2755006..2755245 (-) 240 WP_267070927.1 chaplin -
  OHA73_RS12090 (OHA73_12105) - 2755468..2755713 (-) 246 WP_266721145.1 chaplin -
  OHA73_RS12095 (OHA73_12110) vraR 2755929..2756570 (-) 642 WP_267070926.1 response regulator transcription factor Regulator
  OHA73_RS12100 (OHA73_12115) - 2756563..2757708 (-) 1146 WP_327655039.1 GAF domain-containing sensor histidine kinase -
  OHA73_RS12105 (OHA73_12120) - 2757893..2758588 (+) 696 WP_266721142.1 SDR family oxidoreductase -
  OHA73_RS12110 (OHA73_12125) - 2758588..2759670 (+) 1083 WP_327655040.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OHA73_RS12115 (OHA73_12130) - 2759990..2760733 (+) 744 WP_327655041.1 transglycosylase SLT domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 22910.22 Da        Isoelectric Point: 5.3711

>NTDB_id=647892 OHA73_RS12095 WP_267070926.1 2755929..2756570(-) (vraR) [Streptomyces sp. NBC_00483]
MADQIKVLLVDDHQVVRRGLRTFLEVQGDIEVVGEAADGAEGVARTEELKPDVVLMDVKMPVMDGVDALRRLRELDNPAK
VLIVTSFTEQRTVVPALRAGAAGYVYKDVDPDALAGAIRSVHAGHILLQPEVAGALLAQEETNSGQGRGGSLTEREREVL
GLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGAAG

Nucleotide


Download         Length: 642 bp        

>NTDB_id=647892 OHA73_RS12095 WP_267070926.1 2755929..2756570(-) (vraR) [Streptomyces sp. NBC_00483]
GTGGCTGACCAGATCAAGGTACTGCTGGTCGACGATCACCAGGTCGTCCGCCGGGGCCTGCGCACCTTCCTGGAGGTGCA
GGGCGACATCGAGGTCGTCGGCGAGGCGGCGGACGGCGCCGAAGGAGTCGCCCGCACCGAGGAGTTGAAGCCCGACGTCG
TCCTGATGGACGTCAAGATGCCGGTGATGGACGGAGTCGACGCCCTGCGCCGGCTCCGCGAACTCGACAACCCCGCGAAG
GTGTTGATCGTCACCAGCTTCACTGAGCAGCGCACCGTCGTCCCCGCCCTGCGCGCGGGGGCAGCCGGTTACGTCTACAA
GGACGTGGACCCCGACGCCCTGGCCGGCGCCATCCGTTCCGTCCACGCGGGCCACATCCTGCTGCAACCCGAGGTCGCTG
GTGCCCTGTTGGCCCAGGAGGAGACCAACAGCGGGCAGGGGAGGGGCGGTTCCCTCACGGAGCGCGAGCGCGAGGTGCTC
GGCCTGATCGCCGACGGCCGCTCGAACCGGGAGATCGCCCGCGCCCTCGTCCTCTCCGAGAAAACGGTGAAGACCCATGT
CTCGAACATCCTGATGAAGCTCGACCTGGCGGACCGTACCCAGGCCGCCCTGTGGGCCGTGCGACACGGCGCCGCGGGCT
GA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(151-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

47.619

98.592

0.469
  degU Bacillus subtilis subsp. subtilis str. 168

38.739

100

0.404