Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHN37_RS05175 Genome accession   NZ_CP107878
Coordinates   1130569..1131234 (-) Length   221 a.a.
NCBI ID   WP_266526505.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00485     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1125569..1136234
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHN37_RS05145 (OHN37_05145) - 1125961..1127133 (+) 1173 WP_266526485.1 MFS transporter -
  OHN37_RS05150 (OHN37_05150) - 1127227..1127523 (+) 297 WP_266526487.1 zinc-ribbon domain-containing protein -
  OHN37_RS05155 (OHN37_05155) - 1127571..1128311 (+) 741 WP_266526493.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  OHN37_RS05160 (OHN37_05160) - 1128298..1128690 (-) 393 WP_266526495.1 MarR family transcriptional regulator -
  OHN37_RS05165 (OHN37_05165) - 1128776..1130251 (+) 1476 WP_266526501.1 MFS transporter -
  OHN37_RS05170 (OHN37_05170) - 1130324..1130608 (+) 285 WP_266526503.1 DUF6332 family protein -
  OHN37_RS05175 (OHN37_05175) vraR 1130569..1131234 (-) 666 WP_266526505.1 response regulator transcription factor Regulator
  OHN37_RS05180 (OHN37_05180) - 1131231..1132466 (-) 1236 WP_266526507.1 sensor histidine kinase -
  OHN37_RS05185 (OHN37_05185) - 1132581..1133267 (-) 687 WP_266526509.1 TetR/AcrR family transcriptional regulator -
  OHN37_RS05190 (OHN37_05190) - 1133437..1133886 (+) 450 WP_266526511.1 nitroreductase family deazaflavin-dependent oxidoreductase -
  OHN37_RS05195 (OHN37_05195) - 1133876..1135219 (-) 1344 WP_266526513.1 geranylgeranyl reductase family protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23955.73 Da        Isoelectric Point: 4.8098

>NTDB_id=647693 OHN37_RS05175 WP_266526505.1 1130569..1131234(-) (vraR) [Streptomyces sp. NBC_00485]
MIRVLLADDQSLVRAGFKALLDAQPDIEVAGEASDGEEALGKVRELRPDIVLMDIRMPVLDGLGATRRIIDDEALRGVKV
VMLTTFELDEYVFEAIRSGASGFLVKDTEPDELLRAVRAVVDGDALLSPGVTRRLIAEFAARSKEPAAKGALGELTERER
EVMALVGIGLSNDEIARRLVVSPLTAKTHVSRTMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=647693 OHN37_RS05175 WP_266526505.1 1130569..1131234(-) (vraR) [Streptomyces sp. NBC_00485]
GTGATCCGTGTACTGCTCGCCGATGACCAGTCACTGGTGCGGGCCGGCTTCAAGGCACTGCTCGACGCACAGCCCGACAT
CGAGGTGGCCGGGGAGGCCTCCGACGGTGAGGAGGCGCTGGGCAAGGTGCGTGAACTGCGCCCCGACATCGTCCTGATGG
ACATCCGCATGCCGGTGCTGGACGGGCTGGGGGCGACCCGCCGAATCATCGACGACGAGGCGCTGCGAGGCGTCAAGGTG
GTCATGCTCACCACCTTCGAGCTCGACGAGTACGTCTTCGAGGCGATCCGCTCCGGCGCCTCCGGCTTCCTGGTCAAGGA
CACCGAACCGGACGAACTCCTGCGCGCCGTAAGGGCGGTGGTGGACGGCGACGCGCTGCTCTCGCCCGGTGTGACCCGTC
GCCTGATCGCGGAGTTCGCCGCCCGCTCCAAGGAGCCGGCGGCAAAAGGAGCTCTCGGCGAACTCACCGAGCGGGAACGG
GAGGTGATGGCCCTGGTCGGCATCGGTCTGTCCAACGACGAGATCGCCCGCCGTCTGGTCGTGAGCCCCCTCACGGCGAA
GACCCACGTCAGCCGCACGATGGTCAAGCTCGGCGCCCGGGACAGGGCCCAACTGGTCGTTCTCGCCTACGAGTCGGGGC
TGGTGCGGCCGGGCTGGCTGGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(155-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.605

97.285

0.376
  degU Bacillus subtilis subsp. subtilis str. 168

36.444

100

0.371