Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   SCAZ3_RS01780 Genome accession   NZ_AIDX01000001
Coordinates   388088..389413 (-) Length   441 a.a.
NCBI ID   WP_003044694.1    Uniprot ID   A0AAV3FTH7
Organism   Streptococcus canis FSL Z3-227     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 383088..394413
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCAZ3_RS01740 (SCAZ3_08720) - 383460..383759 (-) 300 WP_000129105.1 hypothetical protein -
  SCAZ3_RS01745 (SCAZ3_08725) - 384142..384339 (-) 198 WP_000208121.1 helix-turn-helix transcriptional regulator -
  SCAZ3_RS01750 (SCAZ3_08730) - 384336..384521 (-) 186 WP_000938679.1 hypothetical protein -
  SCAZ3_RS01755 (SCAZ3_08735) - 384523..385548 (-) 1026 WP_000822468.1 replication initiator protein A -
  SCAZ3_RS11925 (SCAZ3_08740) - 385550..385714 (-) 165 WP_000166480.1 hypothetical protein -
  SCAZ3_RS01760 (SCAZ3_08745) - 385821..386264 (-) 444 WP_000447421.1 hypothetical protein -
  SCAZ3_RS01765 (SCAZ3_08760) - 386530..386787 (-) 258 WP_000191926.1 DUF3850 domain-containing protein -
  SCAZ3_RS01770 (SCAZ3_08765) - 386971..387342 (-) 372 WP_001282474.1 hypothetical protein -
  SCAZ3_RS12155 (SCAZ3_08770) - 387451..387873 (-) 423 WP_003044691.1 ComF family protein -
  SCAZ3_RS01780 (SCAZ3_08775) comFA/cflA 388088..389413 (-) 1326 WP_003044694.1 DEAD/DEAH box helicase Machinery gene
  SCAZ3_RS01785 (SCAZ3_08780) - 389469..390101 (+) 633 WP_003044697.1 YigZ family protein -
  SCAZ3_RS01790 (SCAZ3_08785) cysK 390219..391154 (+) 936 WP_003044700.1 cysteine synthase A -
  SCAZ3_RS01795 (SCAZ3_08790) - 391321..391680 (-) 360 WP_003044703.1 S1 RNA-binding domain-containing protein -
  SCAZ3_RS01800 (SCAZ3_08795) - 391680..393080 (-) 1401 WP_003044706.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  SCAZ3_RS01805 (SCAZ3_08800) - 393117..393758 (-) 642 WP_003044709.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 49783.96 Da        Isoelectric Point: 9.8599

>NTDB_id=64758 SCAZ3_RS01780 WP_003044694.1 388088..389413(-) (comFA/cflA) [Streptococcus canis FSL Z3-227]
MEGIENYYGRLFLENQLPEEGKHLAKPLESIVITKGKVTCQRCRYHISEEERLPSGAYYCRFCLVFGRNQSDKSLYYMSP
KPFPKGSCLKWKGQLTPHQKKISQQLVRNVQTKKPTLVHAVTGAGKTEMIYAAIARVIEAGGWVCLASPRVDVCIEVAKR
LSQAFSCQVCLMHAGSSPYQRSPIIVATTHQLLTFYKAFDLLIIDEVDAFPFVTNVQLNHAANQASKTDAARILLTATST
TTLEKQVKRGEVEKLTLARRFHNHPLVIPQFIRSFAILNNIHCHKIPEIVIKYLREQRQTGYPLLIFLPVITTAEIVTNL
LKKAFPKEKIACVSSQAEEREKDITAFRQGEKTILVTTTILERGVTFPGVDVFVLAAHHRVFTPQSLVQISGRVGRSLER
PTGNLYFFHDGISRAMLKARKEIKEMNQKGYPDDMPTVPTT

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=64758 SCAZ3_RS01780 WP_003044694.1 388088..389413(-) (comFA/cflA) [Streptococcus canis FSL Z3-227]
ATGGAAGGTATTGAAAATTATTACGGTCGTTTATTTTTAGAAAATCAATTGCCAGAAGAAGGAAAGCATCTTGCAAAACC
TTTAGAAAGTATAGTAATTACAAAAGGTAAAGTTACTTGCCAACGATGCCGTTATCACATTAGTGAGGAAGAAAGATTGC
CTAGTGGCGCTTATTATTGCCGCTTCTGTCTTGTCTTTGGCCGCAATCAATCTGATAAATCGCTTTACTATATGTCCCCT
AAGCCATTCCCTAAAGGAAGCTGTCTTAAATGGAAAGGACAATTAACACCTCATCAAAAAAAGATTTCCCAACAGTTGGT
AAGAAATGTACAGACCAAAAAGCCTACCTTGGTTCATGCTGTAACAGGAGCTGGTAAAACAGAAATGATTTATGCAGCTA
TTGCAAGAGTTATTGAAGCAGGTGGCTGGGTATGTTTAGCTAGCCCGCGAGTAGATGTTTGTATCGAAGTGGCCAAACGG
TTATCTCAAGCCTTTTCGTGTCAAGTCTGTTTAATGCATGCTGGATCCTCTCCTTACCAGAGAAGTCCTATTATTGTAGC
AACAACACATCAGTTACTCACTTTTTACAAGGCTTTTGACCTTTTGATTATTGATGAAGTTGATGCTTTTCCATTTGTGA
CAAACGTTCAACTGAATCACGCTGCAAATCAAGCCTCTAAAACAGATGCTGCTAGGATTTTATTAACAGCAACATCAACG
ACAACCTTAGAAAAACAAGTCAAAAGAGGAGAAGTAGAAAAGCTAACATTAGCTAGGCGCTTTCATAATCATCCCTTAGT
TATTCCACAGTTTATCAGAAGTTTTGCTATCTTGAACAATATACACTGCCATAAGATTCCTGAAATAGTCATCAAATACC
TTCGAGAGCAGCGGCAGACAGGTTATCCCCTGTTAATATTTCTTCCTGTTATTACAACAGCAGAAATAGTCACCAATTTG
TTAAAAAAAGCTTTTCCAAAAGAAAAGATAGCTTGTGTTTCAAGTCAAGCAGAAGAGAGGGAGAAAGATATTACTGCCTT
TCGCCAGGGTGAAAAAACTATTTTAGTCACGACAACAATCTTGGAAAGGGGGGTTACCTTTCCTGGTGTTGATGTCTTTG
TACTAGCAGCCCACCATCGAGTTTTCACCCCACAAAGTCTTGTTCAAATCTCGGGACGCGTGGGAAGATCTCTGGAGAGA
CCGACAGGGAACTTATACTTTTTTCATGATGGCATCAGTAGAGCAATGTTGAAGGCTCGAAAAGAAATCAAAGAAATGAA
TCAGAAAGGTTACCCAGATGACATGCCTACTGTGCCAACAACCTAG

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(98-245)

Helicase conserved C-terminal domain (Helicase_C)

(287-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

55.529

96.372

0.535
  comFA/cflA Streptococcus pneumoniae D39

55.529

96.372

0.535
  comFA/cflA Streptococcus pneumoniae R6

55.529

96.372

0.535
  comFA/cflA Streptococcus pneumoniae TIGR4

55.529

96.372

0.535
  comFA/cflA Streptococcus mitis NCTC 12261

54.353

96.372

0.524
  comFA/cflA Streptococcus mitis SK321

53.864

96.825

0.522
  comFA Lactococcus lactis subsp. cremoris KW2

45.476

97.732

0.444
  comFA Latilactobacillus sakei subsp. sakei 23K

40.049

92.29

0.37

Multiple sequence alignment