Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG381_RS12895 Genome accession   NZ_CP107869
Coordinates   2872719..2873360 (-) Length   213 a.a.
NCBI ID   WP_307032607.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00490     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2867719..2878360
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG381_RS12860 (OG381_12865) - 2867764..2868270 (+) 507 WP_327716238.1 HNH endonuclease -
  OG381_RS12865 (OG381_12870) - 2868418..2869365 (-) 948 WP_046257770.1 SPFH domain-containing protein -
  OG381_RS12870 (OG381_12875) - 2869498..2869932 (-) 435 WP_327716239.1 NfeD family protein -
  OG381_RS12875 (OG381_12880) - 2870035..2870832 (-) 798 WP_307032614.1 ABC transporter ATP-binding protein -
  OG381_RS12880 (OG381_12885) - 2870970..2871758 (+) 789 WP_327716240.1 hypothetical protein -
  OG381_RS12885 (OG381_12890) - 2871884..2872123 (-) 240 WP_327716241.1 chaplin -
  OG381_RS12890 (OG381_12895) chpE 2872316..2872561 (-) 246 WP_307032609.1 chaplin ChpE -
  OG381_RS12895 (OG381_12900) vraR 2872719..2873360 (-) 642 WP_307032607.1 response regulator transcription factor Regulator
  OG381_RS12900 (OG381_12905) - 2873353..2874498 (-) 1146 WP_327716242.1 GAF domain-containing sensor histidine kinase -
  OG381_RS12905 (OG381_12910) - 2874687..2875382 (+) 696 WP_327716243.1 SDR family oxidoreductase -
  OG381_RS12910 (OG381_12915) - 2875379..2876476 (+) 1098 WP_327716244.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OG381_RS12915 (OG381_12920) - 2876791..2877525 (+) 735 WP_327716245.1 transglycosylase SLT domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 22909.19 Da        Isoelectric Point: 5.3711

>NTDB_id=647529 OG381_RS12895 WP_307032607.1 2872719..2873360(-) (vraR) [Streptomyces sp. NBC_00490]
MADAIKVLLVDDHQVVRRGLRTFLEVQDDIEVVGEAADGAEGVARAEELKPDVVLMDVKMPGMDGVDALRKLRELNNPAR
VLIVTSFTEQRTVVPALRAGAAGYVYKDVDPDALAGAIRSVHAGHILLQPEVAGALLSQEEANNGQGRGGSLTEREREVL
GLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGVTG

Nucleotide


Download         Length: 642 bp        

>NTDB_id=647529 OG381_RS12895 WP_307032607.1 2872719..2873360(-) (vraR) [Streptomyces sp. NBC_00490]
GTGGCTGACGCAATCAAGGTGCTGCTCGTCGACGACCACCAGGTGGTCCGCCGCGGACTGCGTACCTTCCTCGAAGTGCA
GGACGACATCGAGGTCGTCGGCGAGGCCGCCGACGGCGCCGAAGGAGTCGCCCGCGCCGAGGAACTCAAACCCGACGTCG
TCCTCATGGACGTCAAGATGCCGGGCATGGACGGCGTCGACGCGCTGCGCAAGCTCCGCGAACTGAACAACCCCGCGCGC
GTGCTGATCGTCACCAGCTTCACCGAACAGCGCACGGTGGTCCCGGCGCTGCGCGCGGGCGCCGCGGGGTACGTCTACAA
GGACGTCGACCCCGACGCCCTCGCCGGCGCCATCCGCTCCGTCCACGCCGGGCACATCCTGCTCCAGCCGGAGGTCGCGG
GGGCGCTGCTCTCCCAGGAGGAGGCCAACAACGGCCAGGGAAGAGGCGGCTCGCTCACCGAACGCGAGCGTGAGGTCCTC
GGCCTGATAGCGGACGGCCGCTCGAACCGCGAGATCGCCCGCGCCCTCGTCCTGTCCGAGAAGACCGTCAAGACCCATGT
CTCGAACATCCTGATGAAACTCGACCTGGCGGACCGCACGCAGGCCGCTCTGTGGGCGGTACGTCATGGAGTGACCGGTT
GA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(151-206)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

46.445

99.061

0.46
  degU Bacillus subtilis subsp. subtilis str. 168

38.462

100

0.399