Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG381_RS10025 Genome accession   NZ_CP107869
Coordinates   2226608..2227240 (+) Length   210 a.a.
NCBI ID   WP_327715782.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00490     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2221608..2232240
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG381_RS09995 (OG381_10000) - 2221788..2222318 (-) 531 WP_327715777.1 Clp protease N-terminal domain-containing protein -
  OG381_RS10000 (OG381_10005) - 2222517..2222705 (+) 189 WP_327722771.1 hypothetical protein -
  OG381_RS10005 (OG381_10010) - 2222820..2223248 (+) 429 WP_327715778.1 SRPBCC family protein -
  OG381_RS10010 (OG381_10015) - 2223322..2223945 (-) 624 WP_327715779.1 PadR family transcriptional regulator -
  OG381_RS10015 (OG381_10020) - 2224160..2225287 (+) 1128 WP_327715780.1 ABC transporter substrate-binding protein -
  OG381_RS10020 (OG381_10025) - 2225388..2226611 (+) 1224 WP_327715781.1 sensor histidine kinase -
  OG381_RS10025 (OG381_10030) vraR 2226608..2227240 (+) 633 WP_327715782.1 response regulator transcription factor Regulator
  OG381_RS10030 (OG381_10035) - 2227269..2228897 (-) 1629 WP_327715783.1 thiamine pyrophosphate-binding protein -
  OG381_RS10035 (OG381_10040) - 2228894..2229679 (-) 786 WP_327715784.1 cyclase family protein -
  OG381_RS10040 (OG381_10045) - 2229842..2230651 (+) 810 WP_327715785.1 PhzF family phenazine biosynthesis protein -
  OG381_RS10045 (OG381_10050) - 2230773..2231582 (-) 810 WP_327715786.1 type II CAAX endopeptidase family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 22087.52 Da        Isoelectric Point: 5.1552

>NTDB_id=647525 OG381_RS10025 WP_327715782.1 2226608..2227240(+) (vraR) [Streptomyces sp. NBC_00490]
MTVRLVIADDHAVVRAGLRALLDGEPDLEVIAETGSGEEAVRLAAELKPDVVLMDLRFAGSAVDGIEAVRRLSVEAPAVP
ALMLTSFSGRTDVVRALEAGARGYVLKAGPPEELFRAVRGAAAGALALAPEVVGELVGQVVSPDVALTGREVEVVRLAAE
GLSNRAIAQALFLSEATVKTHLVRVYRKLRVENRAAAVTEAARRGLIQLD

Nucleotide


Download         Length: 633 bp        

>NTDB_id=647525 OG381_RS10025 WP_327715782.1 2226608..2227240(+) (vraR) [Streptomyces sp. NBC_00490]
ATGACCGTACGGCTGGTGATCGCGGACGATCACGCCGTCGTCCGCGCCGGGCTGCGGGCCCTGTTGGACGGGGAACCGGA
TCTCGAGGTGATCGCGGAGACGGGCAGCGGCGAGGAGGCCGTCCGTCTCGCCGCGGAGCTGAAGCCGGACGTCGTGCTGA
TGGACCTCCGGTTCGCGGGTTCCGCTGTCGACGGCATCGAGGCGGTCCGCCGGTTGAGCGTCGAGGCCCCGGCCGTGCCC
GCGCTGATGCTGACGAGCTTCTCCGGGCGGACCGACGTCGTGCGGGCCCTGGAGGCGGGCGCCCGCGGATACGTGCTCAA
GGCCGGGCCGCCCGAGGAGCTCTTCCGGGCGGTCCGTGGCGCCGCCGCCGGCGCCCTGGCCCTCGCCCCCGAGGTCGTCG
GCGAACTCGTCGGCCAGGTGGTCAGCCCCGACGTGGCTCTCACCGGGCGCGAGGTCGAGGTCGTACGGCTGGCGGCGGAG
GGGCTGAGCAACCGGGCCATCGCCCAGGCCCTGTTCCTCAGCGAGGCGACCGTCAAGACCCACCTGGTGCGCGTCTACCG
CAAGCTGAGGGTGGAGAACCGCGCGGCAGCCGTGACGGAGGCCGCGCGCCGGGGACTCATCCAGCTCGACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(146-200)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.863

100

0.39
  degU Bacillus subtilis subsp. subtilis str. 168

36.123

100

0.39