Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG381_RS09500 Genome accession   NZ_CP107869
Coordinates   2118525..2119187 (+) Length   220 a.a.
NCBI ID   WP_327715686.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00490     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2113525..2124187
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG381_RS09475 (OG381_09480) mug 2114603..2115152 (+) 550 Protein_1891 G/U mismatch-specific DNA glycosylase -
  OG381_RS09480 (OG381_09485) - 2115157..2115543 (-) 387 WP_327715682.1 hypothetical protein -
  OG381_RS09485 (OG381_09490) - 2115585..2116310 (-) 726 WP_327715683.1 ABC transporter permease -
  OG381_RS09490 (OG381_09495) - 2116312..2117232 (-) 921 WP_327715684.1 ABC transporter ATP-binding protein -
  OG381_RS09495 (OG381_09500) - 2117341..2118510 (+) 1170 WP_327715685.1 histidine kinase -
  OG381_RS09500 (OG381_09505) vraR 2118525..2119187 (+) 663 WP_327715686.1 response regulator transcription factor Regulator
  OG381_RS09505 (OG381_09510) - 2119287..2120444 (+) 1158 WP_307033680.1 ROK family protein -
  OG381_RS09510 (OG381_09515) - 2120535..2121296 (-) 762 WP_327715687.1 GntR family transcriptional regulator -
  OG381_RS09515 (OG381_09520) - 2121462..2122343 (-) 882 WP_327715688.1 RNA polymerase sigma-70 factor -
  OG381_RS09520 (OG381_09525) - 2122487..2123317 (+) 831 WP_327715689.1 alpha/beta fold hydrolase -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23629.25 Da        Isoelectric Point: 4.7788

>NTDB_id=647524 OG381_RS09500 WP_327715686.1 2118525..2119187(+) (vraR) [Streptomyces sp. NBC_00490]
MPVTVLLVDDEPLVRAGLRAVLEAQPDIEVVGEAADGAAVIPLVRQLRPDVVAMDVRMPLMDGIEATRAVLRTIENPPKI
LVVTTFENDEYVYEALRAGADGFLLKRARPAEIVHAVRLVAEGESLLFPASVRQLAAEYGESGGNRAARAVMERAQLTER
EAEVLRLMARGLSNAEIAERLIVGTETVKSHVSGVLAKLGARDRTQAVIAAYESGFVAPG

Nucleotide


Download         Length: 663 bp        

>NTDB_id=647524 OG381_RS09500 WP_327715686.1 2118525..2119187(+) (vraR) [Streptomyces sp. NBC_00490]
ATGCCGGTCACCGTTCTCCTCGTCGACGACGAACCCCTCGTACGCGCGGGTCTGCGGGCCGTGTTGGAGGCGCAGCCCGA
CATCGAGGTCGTCGGGGAGGCGGCGGACGGGGCCGCCGTGATCCCGCTGGTGCGGCAGCTGCGGCCCGACGTGGTCGCCA
TGGACGTACGGATGCCGCTGATGGACGGGATCGAGGCCACGCGCGCGGTGCTGCGGACGATCGAGAACCCGCCGAAGATC
CTGGTGGTGACGACGTTCGAGAACGACGAGTACGTGTACGAGGCGCTGCGGGCCGGGGCCGACGGGTTCCTGCTGAAGCG
GGCCCGGCCGGCCGAGATCGTGCACGCGGTGCGGCTGGTCGCCGAGGGCGAGTCGCTGCTGTTCCCGGCGTCGGTGCGGC
AGCTCGCCGCCGAGTACGGCGAGAGTGGCGGCAACCGTGCGGCCCGGGCGGTGATGGAGCGGGCCCAGCTGACCGAGCGG
GAGGCCGAGGTACTGCGGCTGATGGCCCGCGGGCTGTCCAACGCGGAGATCGCCGAGCGGCTGATCGTCGGAACGGAGAC
CGTGAAGTCCCACGTCAGCGGCGTACTGGCGAAGCTCGGGGCACGGGACCGCACGCAGGCCGTGATCGCGGCGTACGAGT
CGGGGTTCGTGGCGCCCGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-118)

Bacterial regulatory proteins, luxR family (GerE)

(156-210)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.284

99.091

0.409
  degU Bacillus subtilis subsp. subtilis str. 168

36.404

100

0.377