Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA87_RS25350 Genome accession   NZ_CP107867
Coordinates   5578799..5579467 (-) Length   222 a.a.
NCBI ID   WP_327671152.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00493     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5573799..5584467
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA87_RS25320 (OHA87_25350) - 5573822..5574376 (-) 555 WP_327671147.1 helix-turn-helix domain-containing protein -
  OHA87_RS25325 (OHA87_25355) - 5574496..5574990 (+) 495 WP_327671148.1 nuclear transport factor 2 family protein -
  OHA87_RS25330 (OHA87_25360) - 5575006..5576022 (-) 1017 WP_327671149.1 zinc-binding dehydrogenase -
  OHA87_RS25335 (OHA87_25365) - 5576094..5577302 (-) 1209 WP_327671150.1 NAD(P)-binding protein -
  OHA87_RS25340 (OHA87_25370) - 5577513..5578223 (+) 711 WP_327671151.1 pentapeptide repeat-containing protein -
  OHA87_RS25345 (OHA87_25375) - 5578244..5578744 (-) 501 WP_266712566.1 hypothetical protein -
  OHA87_RS25350 (OHA87_25380) vraR 5578799..5579467 (-) 669 WP_327671152.1 response regulator transcription factor Regulator
  OHA87_RS25355 (OHA87_25385) - 5579464..5580663 (-) 1200 WP_327675576.1 sensor histidine kinase -
  OHA87_RS25360 (OHA87_25390) - 5580994..5581563 (+) 570 WP_327662208.1 heme-binding protein -
  OHA87_RS25365 (OHA87_25395) - 5581633..5582235 (+) 603 WP_327671153.1 ankyrin repeat domain-containing protein -
  OHA87_RS25370 (OHA87_25400) - 5582232..5583383 (+) 1152 WP_327671154.1 hypothetical protein -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 23698.15 Da        Isoelectric Point: 5.1568

>NTDB_id=647461 OHA87_RS25350 WP_327671152.1 5578799..5579467(-) (vraR) [Streptomyces sp. NBC_00493]
MTEPGAEMTQPIRILLCDDHVVVRAGLLALLDSAAGIEVVGEAGTGEEAIALAAKLRPDVVLMDLQLGEGMDGVETTRRL
TTDPEDPATGHRPHVLVLTTYDTDADITRAIEAGATGYLLKAERPEELFAAIHAAAEGRTALSAPVASRVMANMRKPRPT
LTDRERDILAQLAHGLGNREIAKALFISEATVKTHLGRIYDKLGVDTRAGAVSVAKEQRLLP

Nucleotide


Download         Length: 669 bp        

>NTDB_id=647461 OHA87_RS25350 WP_327671152.1 5578799..5579467(-) (vraR) [Streptomyces sp. NBC_00493]
ATGACCGAACCGGGAGCCGAAATGACCCAGCCCATCCGCATCCTCCTCTGTGACGACCACGTCGTCGTTCGTGCCGGGTT
GTTGGCGTTGCTCGACAGTGCGGCGGGGATCGAGGTCGTCGGGGAGGCCGGTACCGGGGAGGAGGCGATCGCGCTCGCCG
CGAAGCTCCGGCCCGACGTCGTCCTCATGGACCTGCAGCTGGGCGAGGGCATGGACGGCGTGGAGACGACCCGCCGCCTC
ACCACCGACCCGGAGGACCCGGCCACCGGGCACCGCCCCCACGTCCTCGTTCTGACCACGTACGACACCGACGCCGACAT
CACCCGCGCCATCGAGGCGGGCGCGACGGGCTATCTGCTCAAGGCGGAGCGGCCCGAGGAGCTGTTCGCGGCGATCCACG
CGGCCGCGGAGGGCCGCACCGCGCTGTCCGCCCCGGTCGCCAGCCGCGTCATGGCCAATATGCGCAAGCCGCGGCCCACC
CTCACCGACCGCGAGCGCGACATCCTCGCCCAGCTGGCGCACGGCCTCGGCAACCGGGAGATCGCCAAGGCCCTGTTCAT
CAGCGAGGCCACGGTCAAGACCCACCTGGGCCGCATCTACGACAAGCTCGGCGTGGACACCCGGGCCGGCGCCGTCTCGG
TCGCGAAGGAGCAGCGGCTACTGCCGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(14-132)

Bacterial regulatory proteins, luxR family (GerE)

(160-215)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.785

96.396

0.374
  degU Bacillus subtilis subsp. subtilis str. 168

35.371

100

0.365