Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHP34_RS05610 Genome accession   NZ_CP107861
Coordinates   1254287..1254946 (-) Length   219 a.a.
NCBI ID   WP_327659658.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00499     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1249287..1259946
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHP34_RS05585 (OHP34_05590) - 1249830..1250669 (-) 840 WP_327659653.1 AraC family transcriptional regulator -
  OHP34_RS05590 (OHP34_05595) - 1250706..1251551 (-) 846 WP_327659654.1 prephenate dehydratase -
  OHP34_RS05595 (OHP34_05600) - 1251774..1252805 (+) 1032 WP_327659655.1 LacI family DNA-binding transcriptional regulator -
  OHP34_RS05600 (OHP34_05605) - 1252949..1253755 (+) 807 WP_327659656.1 MBL fold metallo-hydrolase -
  OHP34_RS05605 (OHP34_05610) - 1253763..1254041 (-) 279 WP_327659657.1 hypothetical protein -
  OHP34_RS05610 (OHP34_05615) vraR 1254287..1254946 (-) 660 WP_327659658.1 response regulator transcription factor Regulator
  OHP34_RS05615 (OHP34_05620) - 1254943..1256121 (-) 1179 WP_406514632.1 sensor histidine kinase -
  OHP34_RS05620 (OHP34_05625) - 1256266..1257213 (-) 948 WP_327659659.1 alpha/beta hydrolase -
  OHP34_RS05625 (OHP34_05630) - 1257408..1258439 (-) 1032 WP_327659660.1 NADPH:quinone reductase -
  OHP34_RS05630 (OHP34_05635) - 1258523..1258861 (-) 339 WP_327659661.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 23690.58 Da        Isoelectric Point: 5.3719

>NTDB_id=647137 OHP34_RS05610 WP_327659658.1 1254287..1254946(-) (vraR) [Streptomyces sp. NBC_00499]
MTEPIRVLVCDDQVLVRTGLVTIIDAQPDLEVVGECGDGKTAVDLAERLRPDVVLMDVRMPVLDGIEATRRLAGSGVRHP
VRVLVVTTFNLDEYVYEALRAGASGFLLKDAPPAQLLLGIRTVATGAALLDPQVTRQLVGRYAARIRPAEDTAPDTPLTP
RELEVLLLIADGLSNSEIAAALLLSQETVKTFVSRILAKLGLRDRVQAVVHAYRRGLVT

Nucleotide


Download         Length: 660 bp        

>NTDB_id=647137 OHP34_RS05610 WP_327659658.1 1254287..1254946(-) (vraR) [Streptomyces sp. NBC_00499]
GTGACCGAGCCGATCCGGGTACTGGTCTGCGACGACCAAGTACTGGTCCGCACCGGCCTGGTGACCATCATCGATGCCCA
GCCCGACCTGGAAGTGGTGGGCGAGTGCGGGGACGGCAAGACGGCCGTCGACCTCGCCGAACGGCTGCGCCCGGACGTCG
TGTTGATGGACGTACGCATGCCGGTGCTCGACGGCATCGAGGCGACCCGGCGGCTCGCCGGTTCCGGGGTGCGGCATCCC
GTCAGGGTGCTCGTCGTCACCACGTTCAACCTGGACGAGTACGTCTACGAGGCACTGCGCGCCGGGGCGAGCGGATTCCT
CCTCAAGGACGCGCCGCCGGCCCAACTACTCCTGGGGATAAGGACCGTGGCCACCGGCGCGGCCCTCCTCGACCCCCAGG
TGACACGTCAGCTCGTGGGCAGATACGCCGCCCGGATCCGGCCCGCCGAGGACACCGCGCCCGACACCCCGCTGACACCG
CGCGAACTGGAGGTCCTGCTCCTCATCGCGGACGGCCTGTCCAACAGTGAGATCGCCGCGGCCCTCCTGCTGAGCCAGGA
GACCGTCAAGACGTTCGTCTCCCGCATCCTCGCCAAACTCGGCCTCCGCGACCGCGTCCAGGCGGTCGTCCATGCCTACC
GCCGGGGGCTGGTGACCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(157-212)

Response regulator receiver domain (Response_reg)

(7-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.72

97.717

0.388
  degU Bacillus subtilis subsp. subtilis str. 168

37.333

100

0.384