Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHQ36_RS11170 Genome accession   NZ_CP107860
Coordinates   2416285..2416926 (-) Length   213 a.a.
NCBI ID   WP_330303574.1    Uniprot ID   A0ABW2VPD9
Organism   Streptomyces sp. NBC_00500     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2411285..2421926
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHQ36_RS11140 (OHQ36_11135) - 2411676..2412182 (+) 507 WP_330303568.1 HNH endonuclease -
  OHQ36_RS11145 (OHQ36_11140) - 2412240..2413175 (-) 936 WP_330303569.1 SPFH domain-containing protein -
  OHQ36_RS11150 (OHQ36_11145) - 2413306..2413740 (-) 435 WP_330303570.1 NfeD family protein -
  OHQ36_RS11155 (OHQ36_11150) - 2413835..2414626 (-) 792 WP_330303571.1 ABC transporter ATP-binding protein -
  OHQ36_RS11160 (OHQ36_11155) - 2414748..2415536 (+) 789 WP_330303572.1 hypothetical protein -
  OHQ36_RS11165 (OHQ36_11160) - 2415833..2416078 (-) 246 WP_330303573.1 chaplin -
  OHQ36_RS11170 (OHQ36_11165) vraR 2416285..2416926 (-) 642 WP_330303574.1 response regulator transcription factor Regulator
  OHQ36_RS11175 (OHQ36_11170) - 2416919..2418076 (-) 1158 WP_330303575.1 GAF domain-containing sensor histidine kinase -
  OHQ36_RS11180 (OHQ36_11175) - 2418264..2418959 (+) 696 WP_330303576.1 SDR family NAD(P)-dependent oxidoreductase -
  OHQ36_RS11185 (OHQ36_11180) - 2418956..2420041 (+) 1086 WP_330303577.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OHQ36_RS11190 (OHQ36_11185) - 2420341..2421090 (+) 750 WP_330303578.1 transglycosylase SLT domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 22911.24 Da        Isoelectric Point: 5.3758

>NTDB_id=647053 OHQ36_RS11170 WP_330303574.1 2416285..2416926(-) (vraR) [Streptomyces sp. NBC_00500]
MADAIKVLLVDDHQVVRRGLRTFLEVQDDIEVVGEASDGAEGIARAEELKPDVVLMDVKMPGMDGIEALRKLRELANPAR
VLIVTSFTEQRTVVPALRAGAAGYVYKDVDPDALAGAIRSVHAGHILLQPEVAGALLSQEEANSGQGRGGSLTEREREVL
TLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGVAG

Nucleotide


Download         Length: 642 bp        

>NTDB_id=647053 OHQ36_RS11170 WP_330303574.1 2416285..2416926(-) (vraR) [Streptomyces sp. NBC_00500]
GTGGCTGACGCAATCAAGGTGCTGCTCGTCGACGACCACCAAGTGGTCCGCCGGGGTCTGCGCACCTTCCTCGAAGTACA
GGACGACATCGAGGTCGTGGGAGAGGCGTCCGACGGCGCCGAAGGGATCGCCCGCGCCGAGGAGTTGAAGCCCGACGTCG
TCCTCATGGACGTCAAGATGCCGGGCATGGACGGTATCGAGGCGCTGCGCAAGCTCCGCGAACTCGCCAACCCCGCGCGC
GTGCTGATCGTCACCAGCTTCACCGAGCAGCGCACGGTCGTCCCCGCCCTGCGCGCGGGCGCCGCCGGATATGTGTACAA
GGACGTGGACCCCGACGCCCTCGCCGGCGCCATCCGCTCCGTGCACGCCGGACACATCCTGCTGCAGCCCGAGGTCGCGG
GCGCGCTGCTGTCCCAGGAGGAGGCCAACTCGGGCCAGGGGAGAGGCGGTTCACTCACCGAGCGGGAGCGCGAGGTGCTC
ACCCTGATCGCGGACGGCCGCTCCAACCGCGAGATCGCCCGCGCGCTCGTCCTCTCCGAGAAGACCGTCAAGACGCATGT
CTCGAACATCCTGATGAAACTCGACCTCGCGGACCGGACCCAGGCCGCGCTCTGGGCCGTACGACATGGGGTGGCAGGCT
GA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(151-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

46.445

99.061

0.46
  degU Bacillus subtilis subsp. subtilis str. 168

38.462

100

0.399