Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   KB232_RS07565 Genome accession   NZ_CP090989
Coordinates   1618860..1619732 (-) Length   290 a.a.
NCBI ID   WP_002484839.1    Uniprot ID   A0A4Y7VXK4
Organism   Staphylococcus epidermidis strain 52B     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1580400..1651274 1618860..1619732 within 0


Gene organization within MGE regions


Location: 1580400..1651274
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KB232_RS07420 (KB232_07420) yfmF 1581440..1582711 (-) 1272 WP_002439538.1 EF-P 5-aminopentanol modification-associated protein YfmF -
  KB232_RS07425 (KB232_07425) - 1582742..1583455 (-) 714 WP_002439536.1 GntR family transcriptional regulator -
  KB232_RS07430 (KB232_07430) - 1583458..1585851 (-) 2394 WP_049392165.1 DNA translocase FtsK -
  KB232_RS07435 (KB232_07435) rnjB 1586117..1587790 (-) 1674 WP_002457357.1 ribonuclease J2 -
  KB232_RS07440 (KB232_07440) pnp 1588158..1590263 (-) 2106 WP_001832554.1 polyribonucleotide nucleotidyltransferase -
  KB232_RS07445 (KB232_07445) rpsO 1590395..1590664 (-) 270 WP_002439528.1 30S ribosomal protein S15 -
  KB232_RS07450 (KB232_07450) - 1590784..1591755 (-) 972 WP_001832563.1 bifunctional riboflavin kinase/FAD synthetase -
  KB232_RS07455 (KB232_07455) truB 1591771..1592688 (-) 918 WP_002456563.1 tRNA pseudouridine(55) synthase TruB -
  KB232_RS07460 (KB232_07460) rbfA 1592826..1593176 (-) 351 WP_001829509.1 30S ribosome-binding factor RbfA -
  KB232_RS07465 (KB232_07465) infB 1593479..1595641 (-) 2163 WP_002468903.1 translation initiation factor IF-2 -
  KB232_RS07470 (KB232_07470) - 1595646..1595963 (-) 318 WP_002439520.1 YlxQ family RNA-binding protein -
  KB232_RS07475 (KB232_07475) rnpM 1595963..1596247 (-) 285 WP_001829465.1 RNase P modulator RnpM -
  KB232_RS07480 (KB232_07480) nusA 1596265..1597488 (-) 1224 WP_002456565.1 transcription termination factor NusA -
  KB232_RS07485 (KB232_07485) rimP 1597509..1597976 (-) 468 WP_002439519.1 ribosome maturation factor RimP -
  KB232_RS07490 (KB232_07490) - 1598155..1602465 (-) 4311 WP_002456566.1 PolC-type DNA polymerase III -
  KB232_RS07495 (KB232_07495) - 1602715..1604418 (-) 1704 WP_001829513.1 proline--tRNA ligase -
  KB232_RS07500 (KB232_07500) rseP 1604437..1605723 (-) 1287 WP_001829501.1 RIP metalloprotease RseP -
  KB232_RS07505 (KB232_07505) - 1605957..1606739 (-) 783 WP_001829499.1 phosphatidate cytidylyltransferase -
  KB232_RS07510 (KB232_07510) - 1606743..1607513 (-) 771 WP_001832561.1 isoprenyl transferase -
  KB232_RS07515 (KB232_07515) frr 1607734..1608288 (-) 555 WP_001829472.1 ribosome recycling factor -
  KB232_RS07520 (KB232_07520) pyrH 1608305..1609027 (-) 723 WP_002439511.1 UMP kinase -
  KB232_RS07525 (KB232_07525) tsf 1609168..1610046 (-) 879 WP_002439509.1 translation elongation factor Ts -
  KB232_RS07530 (KB232_07530) rpsB 1610198..1610986 (-) 789 WP_001832557.1 30S ribosomal protein S2 -
  KB232_RS07535 (KB232_07535) codY 1611349..1612119 (-) 771 WP_002439506.1 GTP-sensing pleiotropic transcriptional regulator CodY -
  KB232_RS07540 (KB232_07540) hslU 1612143..1613546 (-) 1404 WP_001829474.1 ATP-dependent protease ATPase subunit HslU -
  KB232_RS07545 (KB232_07545) hslV 1613615..1614157 (-) 543 WP_001829498.1 ATP-dependent protease subunit HslV -
  KB232_RS07550 (KB232_07550) xerC 1614161..1615021 (-) 861 WP_002439503.1 tyrosine recombinase XerC -
  KB232_RS07555 (KB232_07555) trmFO 1615276..1616583 (-) 1308 WP_001832560.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  KB232_RS07560 (KB232_07560) topA 1616608..1618677 (-) 2070 WP_001829508.1 type I DNA topoisomerase -
  KB232_RS07565 (KB232_07565) dprA 1618860..1619732 (-) 873 WP_002484839.1 DNA-processing protein DprA Machinery gene
  KB232_RS07575 (KB232_07575) sucD 1620537..1621445 (-) 909 WP_002446283.1 succinate--CoA ligase subunit alpha -
  KB232_RS07580 (KB232_07580) sucC 1621467..1622633 (-) 1167 WP_002439496.1 ADP-forming succinate--CoA ligase subunit beta -
  KB232_RS07585 (KB232_07585) - 1622741..1623511 (-) 771 WP_001829514.1 ribonuclease HII -
  KB232_RS07590 (KB232_07590) ylqF 1623516..1624379 (-) 864 WP_002468554.1 ribosome biogenesis GTPase YlqF -
  KB232_RS07595 (KB232_07595) - 1624400..1624549 (-) 150 WP_162152279.1 hypothetical protein -
  KB232_RS07600 (KB232_07600) - 1624708..1627308 (+) 2601 WP_010959172.1 YfhO family protein -
  KB232_RS07605 (KB232_07605) - 1627301..1629904 (+) 2604 WP_020368058.1 YfhO family protein -
  KB232_RS07610 (KB232_07610) rplS 1630434..1630784 (-) 351 WP_002436293.1 50S ribosomal protein L19 -
  KB232_RS07615 (KB232_07615) trmD 1630890..1631627 (-) 738 WP_001829466.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  KB232_RS07620 (KB232_07620) rimM 1631627..1632130 (-) 504 WP_001832559.1 ribosome maturation factor RimM -
  KB232_RS07625 (KB232_07625) rpsP 1632257..1632532 (-) 276 WP_002439483.1 30S ribosomal protein S16 -
  KB232_RS07630 (KB232_07630) ffh 1632840..1634207 (-) 1368 WP_001830113.1 signal recognition particle protein -
  KB232_RS07635 (KB232_07635) - 1634238..1634570 (-) 333 WP_002457379.1 putative DNA-binding protein -
  KB232_RS07640 (KB232_07640) ftsY 1634572..1635798 (-) 1227 WP_001830080.1 signal recognition particle-docking protein FtsY -
  KB232_RS07645 (KB232_07645) smc 1635795..1639364 (-) 3570 WP_002502436.1 chromosome segregation protein SMC -
  KB232_RS07650 (KB232_07650) rnc 1639491..1640228 (-) 738 WP_002470220.1 ribonuclease III -
  KB232_RS07655 (KB232_07655) - 1640343..1640576 (-) 234 WP_001830184.1 acyl carrier protein -
  KB232_RS07660 (KB232_07660) fabG 1640803..1641537 (-) 735 WP_001830161.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  KB232_RS07665 (KB232_07665) fabD 1641530..1642456 (-) 927 WP_001830062.1 ACP S-malonyltransferase -
  KB232_RS07670 (KB232_07670) plsX 1642458..1643435 (-) 978 WP_001830112.1 phosphate acyltransferase PlsX -
  KB232_RS07675 (KB232_07675) fapR 1643437..1643997 (-) 561 WP_001830099.1 transcription factor FapR -
  KB232_RS07680 (KB232_07680) recG 1644156..1646204 (-) 2049 WP_020368084.1 ATP-dependent DNA helicase RecG -
  KB232_RS07685 (KB232_07685) fakA 1646408..1648066 (-) 1659 WP_002489351.1 fatty acid kinase catalytic subunit FakA -
  KB232_RS07690 (KB232_07690) - 1648081..1648455 (-) 375 WP_001830156.1 Asp23/Gls24 family envelope stress response protein -
  KB232_RS07695 (KB232_07695) rpmB 1648813..1649001 (+) 189 WP_001830107.1 50S ribosomal protein L28 -
  KB232_RS07700 (KB232_07700) - 1649084..1649719 (-) 636 WP_002489340.1 thiamine diphosphokinase -
  KB232_RS07705 (KB232_07705) rpe 1649724..1650368 (-) 645 WP_001830173.1 ribulose-phosphate 3-epimerase -
  KB232_RS07710 (KB232_07710) rsgA 1650369..1651244 (-) 876 WP_002456227.1 ribosome small subunit-dependent GTPase A -

Sequence

Protein


Download         Length: 290 a.a.        Molecular weight: 33717.61 Da        Isoelectric Point: 9.3616

>NTDB_id=647006 KB232_RS07565 WP_002484839.1 1618860..1619732(-) (dprA) [Staphylococcus epidermidis strain 52B]
MIQQTMLKLYWANFTTAQLHHLTSTYPDFLSENVFHQHDMIKRWLTERNSERLWNKYERFKELKLMDIIKEMKKANVSFT
TYFDDNYPSLCKEMYDYPYVIFYKGNPQFFNHSHSLAVIGSRNATQYTSQSLNYLFPSFRQLNMAIVSGLARGADSVAHQ
TALKYLLPTIGVLGFGHCYHYPKATLNLRTKVERNGLVISEYPPFSPISKHKFPERNRLISGLSRGVLITEAEERSGSQI
TIDCALEQNRNVYVLPGSMFNKMTKGNLRRINEGAQVVIDESSILYDYLF

Nucleotide


Download         Length: 873 bp        

>NTDB_id=647006 KB232_RS07565 WP_002484839.1 1618860..1619732(-) (dprA) [Staphylococcus epidermidis strain 52B]
TTGATACAACAGACGATGTTAAAACTATATTGGGCAAATTTCACTACGGCACAACTTCATCATCTTACAAGTACATATCC
TGACTTTCTATCAGAAAACGTATTTCATCAACATGACATGATAAAAAGGTGGCTTACAGAGCGTAATTCTGAAAGGCTAT
GGAACAAATATGAACGTTTCAAAGAATTAAAGCTGATGGACATTATTAAAGAAATGAAAAAAGCAAATGTTAGTTTTACA
ACATACTTTGATGATAACTACCCTTCTCTTTGCAAAGAAATGTATGATTATCCTTATGTGATATTCTACAAAGGAAATCC
ACAGTTCTTTAATCATTCTCACTCTTTAGCTGTAATTGGCTCACGTAATGCCACACAATATACAAGTCAATCTTTAAACT
ATCTTTTTCCTTCATTTAGACAATTAAATATGGCGATTGTTTCTGGATTAGCGCGCGGTGCAGATAGTGTAGCACATCAA
ACCGCACTTAAATACCTATTACCAACTATTGGCGTACTTGGATTTGGCCATTGTTATCATTATCCTAAAGCAACCTTAAA
TTTAAGAACTAAAGTTGAAAGGAATGGCTTAGTGATAAGTGAATATCCACCATTTTCTCCTATAAGTAAGCATAAATTTC
CTGAAAGAAACAGGCTTATAAGTGGTCTGTCCAGAGGGGTACTTATAACTGAGGCTGAAGAAAGAAGTGGTAGTCAAATC
ACTATCGATTGTGCTTTAGAGCAAAATAGAAATGTTTATGTTCTACCTGGTTCAATGTTCAACAAAATGACTAAAGGTAA
TTTAAGAAGGATAAATGAAGGTGCTCAAGTTGTTATAGATGAAAGTAGTATATTATATGATTATCTATTTTAG

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4Y7VXK4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus MW2

56.944

99.31

0.566
  dprA Staphylococcus aureus N315

56.944

99.31

0.566