Detailed information NTG0646994

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OG490_RS21295
• Genome accession: NZ_CP107855
• Coordinates: 4583039..4584163 (-)
• Length: 374 a.a.
• NCBI ID: WP_330297894.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_00503
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4578039..4589163

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OG490_RS21265 (OG490_21240)	cseB	4578193..4578906 (-)	714	WP_330297890.1	two-component system response regulator CseB	-
OG490_RS21270 (OG490_21245)	-	4578960..4579619 (-)	660	WP_330300999.1	hypothetical protein	-
OG490_RS21275 (OG490_21250)	-	4579646..4580206 (-)	561	WP_069920779.1	SigE family RNA polymerase sigma factor	-
OG490_RS21280 (OG490_21255)	-	4580382..4581305 (-)	924	WP_330297891.1	A/G-specific adenine glycosylase	-
OG490_RS21285 (OG490_21260)	-	4581335..4581943 (-)	609	WP_330297892.1	phosphatase PAP2 family protein	-
OG490_RS21290 (OG490_21265)	-	4582114..4582935 (+)	822	WP_330297893.1	hypothetical protein	-
OG490_RS21295 (OG490_21270)	disA	4583039..4584163 (-)	1125	WP_330297894.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OG490_RS21300 (OG490_21275)	radA/sms	4584425..4585840 (-)	1416	WP_330297895.1	DNA repair protein RadA	Machinery gene
OG490_RS21305 (OG490_21280)	-	4586117..4587979 (+)	1863	WP_330297896.1	hypothetical protein	-
OG490_RS21310 (OG490_21285)	-	4587992..4588864 (-)	873	WP_330297897.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40330.32 Da
• Isoelectric Point: 5.1222

>NTDB_id=646994 OG490_RS21295 WP_330297894.1 4583039..4584163(-) (disA) [Streptomyces sp. NBC_00503]
MAAKDGAAASGKSGASSKQEAMMRASLSAVAPGQPLRDGLERIVRGNTGGLIVLGMDKSVEAMCTGGFVLDVEFTATRLR
ELCKLDGALILDKDLTKILRAGVQLVPDASIHTEETGTRHRTADRVSKQCGFPVVSVSQSMRLIALYVDGERRVLEESGA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVGAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELTV
GIEQERELVIRDYVPEPTAKRSRTVEEALPALDALTHPELLELAIVAKALGYTGSPETLDSAVSPRGYRLLAKVPRLPGA
IIERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=646994 OG490_RS21295 WP_330297894.1 4583039..4584163(-) (disA) [Streptomyces sp. NBC_00503]
GTGGCAGCCAAGGACGGGGCAGCAGCATCCGGGAAGTCGGGCGCGAGCTCCAAGCAGGAGGCCATGATGCGTGCCTCGCT
GAGCGCGGTCGCACCCGGTCAGCCGCTGCGCGACGGCCTCGAACGGATCGTCCGCGGCAACACCGGCGGGCTCATCGTGC
TCGGCATGGACAAGTCCGTGGAAGCGATGTGCACGGGCGGTTTCGTCCTGGACGTGGAGTTCACCGCGACCCGGTTGCGC
GAGCTGTGCAAGCTCGACGGCGCGCTGATCCTGGACAAGGACCTCACCAAGATCCTGCGGGCGGGCGTGCAGCTGGTTCC
GGACGCGTCCATCCACACGGAGGAGACCGGCACCCGGCACCGCACCGCGGACCGCGTCTCGAAGCAGTGCGGGTTCCCGG
TGGTCTCGGTGTCGCAGTCGATGCGGCTGATCGCGCTGTACGTGGACGGCGAGCGGCGCGTGCTGGAGGAGTCCGGGGCG
ATCCTGTCGCGGGCGAACCAGGCGCTGGCCACGCTGGAGCGGTACAAGCTCCGCCTGGACGAGGTGGCGGGCACGCTGTC
CGCGCTGGAGATCGAGGACCTGGTGACGGTCCGCGACGTCGGCGCGGTGGCGCAGCGGCTGGAAATGGTCCGCCGGATCG
CGACGGAAATCGCGGAATACGTGGTGGAACTGGGCACGGACGGCCGACTGCTCTCGCTCCAGCTGGACGAGCTGACGGTC
GGGATCGAGCAGGAGCGCGAGCTGGTCATCCGGGACTACGTGCCGGAGCCGACGGCGAAGCGGTCGCGGACGGTGGAGGA
AGCTCTGCCCGCGCTGGACGCGCTGACCCACCCGGAGCTGCTGGAACTGGCGATCGTGGCGAAGGCGCTGGGGTACACCG
GTTCGCCGGAGACGCTCGACTCGGCGGTGTCCCCGCGGGGCTACCGGCTGCTGGCGAAGGTTCCCCGGCTGCCGGGCGCG
ATCATCGAGCGGCTGGTGGAGCACTTCGGCGGGCTGCAGAAGCTGCTGGCCGCCTCCGTGGACGACCTGCAGACGGTCGA
CGGGGTCGGCGAGGCCCGTGCCCGTAGCGTCCGCGAGGGGCTGTCGCGGCTGGCGGAATCCTCGATCCTGGAGCGGTACG
TCTAG

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• Helix-hairpin-helix motif (HHH_2) (324-359)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.983	96.524	0.444