Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA84_RS20260 Genome accession   NZ_CP107845
Coordinates   4376723..4377343 (-) Length   206 a.a.
NCBI ID   WP_053681157.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00513     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4371723..4382343
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA84_RS20240 (OHA84_20190) - 4372290..4373282 (-) 993 WP_266974023.1 zinc-binding dehydrogenase -
  OHA84_RS20245 (OHA84_20195) - 4373508..4374182 (+) 675 WP_266970400.1 pentapeptide repeat-containing protein -
  OHA84_RS20250 (OHA84_20200) - 4374202..4374705 (-) 504 WP_053678538.1 hypothetical protein -
  OHA84_RS20255 (OHA84_20205) - 4374767..4375939 (-) 1173 WP_266970398.1 M4 family metallopeptidase -
  OHA84_RS20260 (OHA84_20210) vraR 4376723..4377343 (-) 621 WP_053681157.1 response regulator transcription factor Regulator
  OHA84_RS20265 (OHA84_20215) - 4377340..4378677 (-) 1338 WP_266970395.1 sensor histidine kinase -
  OHA84_RS20270 (OHA84_20220) - 4378908..4379468 (+) 561 WP_053681152.1 heme-binding protein -
  OHA84_RS20275 (OHA84_20225) - 4379589..4381001 (+) 1413 WP_266970393.1 M1 family metallopeptidase -
  OHA84_RS20280 (OHA84_20230) - 4381113..4381643 (-) 531 WP_053681148.1 GNAT family N-acetyltransferase -
  OHA84_RS20285 (OHA84_20235) - 4381716..4382291 (-) 576 WP_053681146.1 TerD family protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 21779.04 Da        Isoelectric Point: 5.3171

>NTDB_id=646914 OHA84_RS20260 WP_053681157.1 4376723..4377343(-) (vraR) [Streptomyces sp. NBC_00513]
MTTILLCDDHVVVRAGLLALLGSEPDIEVLGEAGSGEEAVALAAKLRPDVVLMDLQLGEGIDGVEATRRITALTDPPHVL
VLTTYDTDADITRAIGAGATGYLLKAERPEELFAAIHSAAAGRTTLSAPVASRVMAHMRGTRPTLTDRELDILGQLARGL
GNRDIARALFISEATVKTHLGRIYDKLGVDTRAGAVSVAKEQRLLP

Nucleotide


Download         Length: 621 bp        

>NTDB_id=646914 OHA84_RS20260 WP_053681157.1 4376723..4377343(-) (vraR) [Streptomyces sp. NBC_00513]
ATGACCACGATCCTGCTCTGCGACGACCACGTGGTGGTCCGCGCCGGCCTGCTCGCCCTGCTGGGCAGCGAACCCGACAT
CGAGGTGCTCGGCGAAGCCGGCAGCGGCGAGGAAGCCGTCGCACTGGCCGCCAAACTCCGCCCCGACGTGGTCCTGATGG
ACCTCCAACTCGGCGAGGGCATCGACGGCGTCGAAGCCACCCGCCGCATCACGGCGCTCACCGACCCGCCGCACGTGCTG
GTACTCACCACCTACGACACCGACGCCGACATCACCCGGGCCATCGGGGCGGGCGCCACCGGCTACCTCCTCAAGGCGGA
ACGCCCCGAGGAACTCTTCGCCGCGATCCACTCCGCGGCGGCCGGCCGCACCACGCTCTCCGCGCCGGTGGCCAGCCGGG
TGATGGCCCACATGCGGGGCACCCGGCCCACCCTGACGGACCGTGAACTGGACATCCTGGGCCAACTGGCCCGCGGCCTC
GGCAACCGGGACATCGCCCGGGCCCTGTTCATCAGCGAAGCCACGGTCAAGACCCACCTGGGCCGCATCTACGACAAGCT
CGGCGTGGACACGCGCGCGGGGGCGGTGTCGGTGGCGAAGGAACAGCGCCTGCTGCCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(144-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.35

100

0.384
  degU Bacillus subtilis subsp. subtilis str. 168

35.023

100

0.369