Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHN73_RS41395 Genome accession   NZ_CP107839
Coordinates   8929423..8930088 (+) Length   221 a.a.
NCBI ID   WP_266526505.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00519     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8924423..8935088
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHN73_RS41375 (OHN73_41265) - 8925456..8926781 (+) 1326 WP_406322450.1 geranylgeranyl reductase family protein -
  OHN73_RS41380 (OHN73_41270) - 8926771..8927220 (-) 450 WP_266526511.1 nitroreductase family deazaflavin-dependent oxidoreductase -
  OHN73_RS41385 (OHN73_41275) - 8927390..8928076 (+) 687 WP_406322452.1 TetR/AcrR family transcriptional regulator -
  OHN73_RS41390 (OHN73_41280) - 8928191..8929426 (+) 1236 WP_266587137.1 sensor histidine kinase -
  OHN73_RS41395 (OHN73_41285) vraR 8929423..8930088 (+) 666 WP_266526505.1 response regulator transcription factor Regulator
  OHN73_RS41400 (OHN73_41290) - 8930049..8930333 (-) 285 WP_266587139.1 DUF6332 family protein -
  OHN73_RS41405 (OHN73_41295) - 8930406..8931881 (-) 1476 WP_266587141.1 MFS transporter -
  OHN73_RS41410 (OHN73_41300) - 8931967..8932359 (+) 393 WP_266526495.1 MarR family winged helix-turn-helix transcriptional regulator -
  OHN73_RS41415 (OHN73_41305) - 8932346..8933086 (-) 741 WP_266526493.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  OHN73_RS41420 (OHN73_41310) - 8933134..8933430 (-) 297 WP_266526487.1 zinc-ribbon domain-containing protein -
  OHN73_RS41425 (OHN73_41315) - 8933524..8934732 (-) 1209 WP_405623385.1 MFS transporter -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23955.73 Da        Isoelectric Point: 4.8098

>NTDB_id=646862 OHN73_RS41395 WP_266526505.1 8929423..8930088(+) (vraR) [Streptomyces sp. NBC_00519]
MIRVLLADDQSLVRAGFKALLDAQPDIEVAGEASDGEEALGKVRELRPDIVLMDIRMPVLDGLGATRRIIDDEALRGVKV
VMLTTFELDEYVFEAIRSGASGFLVKDTEPDELLRAVRAVVDGDALLSPGVTRRLIAEFAARSKEPAAKGALGELTERER
EVMALVGIGLSNDEIARRLVVSPLTAKTHVSRTMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=646862 OHN73_RS41395 WP_266526505.1 8929423..8930088(+) (vraR) [Streptomyces sp. NBC_00519]
GTGATCCGTGTACTGCTCGCCGATGACCAGTCACTGGTGCGGGCCGGCTTCAAGGCACTGCTCGACGCACAGCCCGACAT
CGAGGTGGCCGGGGAGGCCTCCGACGGTGAGGAGGCGCTGGGCAAGGTGCGTGAACTGCGCCCCGACATCGTCCTGATGG
ACATCCGCATGCCGGTGCTGGACGGGCTGGGGGCGACCCGCCGGATCATCGACGACGAGGCGCTGCGAGGCGTCAAGGTG
GTCATGCTCACCACCTTCGAGCTCGACGAGTACGTCTTCGAGGCGATCCGCTCCGGCGCCTCCGGCTTCCTGGTCAAGGA
CACCGAACCGGACGAACTCCTGCGCGCCGTAAGGGCGGTGGTGGACGGCGACGCGCTGCTCTCGCCCGGTGTGACCCGTC
GCCTGATCGCGGAGTTCGCGGCCCGCTCCAAGGAGCCGGCGGCAAAAGGAGCTCTCGGCGAACTCACCGAGCGGGAACGG
GAGGTGATGGCCCTGGTCGGCATCGGTCTGTCCAACGACGAGATCGCCCGCCGTCTGGTCGTGAGCCCCCTCACGGCGAA
GACCCACGTCAGCCGCACGATGGTCAAGCTCGGCGCCCGGGACAGGGCCCAACTGGTCGTTCTCGCCTACGAGTCGGGGC
TGGTGCGGCCGGGCTGGCTGGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(155-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.605

97.285

0.376
  degU Bacillus subtilis subsp. subtilis str. 168

36.444

100

0.371