Detailed information NTG0646737

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OHS17_RS14675
• Genome accession: NZ_CP107836
• Coordinates: 3258851..3259975 (+)
• Length: 374 a.a.
• NCBI ID: WP_026171409.1
• Uniprot ID: A0ABY6PU31
• Organism: Streptomyces sp. NBC_00523
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3253851..3264975

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OHS17_RS14660 (OHS17_14680)	-	3254374..3255246 (+)	873	WP_330312546.1	hypothetical protein	-
OHS17_RS14665 (OHS17_14685)	-	3255275..3257158 (-)	1884	WP_330312547.1	hypothetical protein	-
OHS17_RS14670 (OHS17_14690)	radA/sms	3257293..3258705 (+)	1413	WP_330312548.1	DNA repair protein RadA	Machinery gene
OHS17_RS14675 (OHS17_14695)	disA	3258851..3259975 (+)	1125	WP_026171409.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OHS17_RS14680 (OHS17_14700)	-	3260012..3260779 (-)	768	WP_330315259.1	hypothetical protein	-
OHS17_RS14685 (OHS17_14705)	-	3261112..3262014 (+)	903	WP_330312549.1	A/G-specific adenine glycosylase	-
OHS17_RS14690 (OHS17_14710)	-	3262321..3262869 (+)	549	WP_018102282.1	SigE family RNA polymerase sigma factor	-
OHS17_RS14695 (OHS17_14715)	-	3262857..3263582 (+)	726	WP_161206639.1	hypothetical protein	-
OHS17_RS14700 (OHS17_14720)	cseB	3263593..3264297 (+)	705	WP_073864177.1	two-component system response regulator CseB	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40422.37 Da
• Isoelectric Point: 5.0161

>NTDB_id=646737 OHS17_RS14675 WP_026171409.1 3258851..3259975(+) (disA) [Streptomyces sp. NBC_00523]
MAASDRAASPGKSGQTTGNEALMRASLSAVAPGMALRDGLERILRGNTGGLIVLGMDKTVESMCTGGFVLDVEFTATRLR
ELAKLDGALILDKDMTKILRAGVQLVPDASIPTEETGTRHRTADRVSKQCNFPVVSVSQSMRLIALYVNGERRVLEESAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVAEALTELDSLTHTELLELPVVARALGYSGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=646737 OHS17_RS14675 WP_026171409.1 3258851..3259975(+) (disA) [Streptomyces sp. NBC_00523]
GTGGCAGCCAGCGACCGGGCAGCATCGCCCGGAAAGTCCGGCCAAACCACGGGCAACGAGGCGCTGATGCGCGCCTCGTT
GAGCGCCGTCGCGCCCGGAATGGCCCTGCGGGACGGCCTGGAGCGCATTCTCCGCGGCAACACCGGGGGTCTGATCGTGC
TCGGCATGGACAAGACCGTCGAGTCGATGTGCACGGGCGGCTTCGTGCTGGACGTGGAGTTCACCGCGACCCGGCTGCGG
GAGCTGGCCAAGCTGGACGGCGCCCTGATCCTCGACAAGGACATGACGAAGATCCTGCGCGCCGGGGTGCAGCTGGTCCC
GGACGCGTCGATCCCCACCGAGGAGACCGGCACCCGGCACCGCACCGCGGACCGGGTCTCGAAGCAGTGCAATTTCCCGG
TCGTCTCGGTCTCCCAGTCGATGCGCCTGATCGCGCTGTACGTGAACGGGGAGCGGCGGGTCCTGGAGGAGTCGGCGGCG
ATCCTGTCCCGCGCCAACCAGGCCCTCGCCACGCTGGAGCGGTACAAGCTGCGGCTGGACGAGGTCGCCGGGACGCTTTC
CGCGCTGGAGATCGAGGACCTGGTGACCGTCCGGGACGTGACGGCGGTGGCCCAGCGCCTGGAGATGGTCCGCCGGATCG
CGACGGAGATCGCGGAGTACGTGGTGGAGCTCGGCACCGACGGGCGGCTGCTGTCGCTCCAGCTGGACGAGCTGATCGCG
GGCGTGGAGCCGGAGCGCGAGCTGGTCGTGCGGGACTACGTGCCGGAGCCGACCGCGAAGCGTTCGCGCACGGTGGCGGA
GGCGCTGACCGAGCTGGACTCGCTGACCCACACGGAGCTGCTCGAACTTCCGGTGGTGGCGCGGGCGCTGGGCTACAGCG
GCTCGCCCGAGACGCTGGACTCGGCGGTGTCGCCGCGCGGTTTCCGGCTGCTGGCGAAGGTGCCGCGGCTGCCCGGCGCG
ATCATCGACCGGCTGGTGGAGCACTTCGGCGGTCTGCAGAAGCTGCTCGCGGCGAGCGTGGACGACCTCCAGACGGTCGA
CGGGGTCGGCGAGGCCCGGGCGCGCAGTGTGCGCGAGGGCCTGTCCCGGCTGGCCGAGTCGTCCATCCTCGAACGGTACG
TGTAA

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	44.598	96.524	0.43