Detailed information NTG0646590

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: OHS33_RS17245
• Genome accession: NZ_CP107819
• Coordinates: 3958131..3960716 (-)
• Length: 861 a.a.
• NCBI ID: WP_330331301.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_00536
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3953131..3965716

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OHS33_RS17225 (OHS33_17220)	-	3953672..3954193 (-)	522	WP_330331297.1	DUF2617 family protein	-
OHS33_RS17230 (OHS33_17225)	-	3954962..3956164 (+)	1203	WP_330331298.1	pyridoxal phosphate-dependent aminotransferase	-
OHS33_RS17235 (OHS33_17230)	-	3956232..3957407 (+)	1176	WP_330331299.1	hypothetical protein	-
OHS33_RS17240 (OHS33_17235)	-	3957438..3957995 (-)	558	WP_330331300.1	YbjN domain-containing protein	-
OHS33_RS17245 (OHS33_17240)	clpC	3958131..3960716 (-)	2586	WP_330331301.1	ATP-dependent chaperone ClpB	Regulator
OHS33_RS17250 (OHS33_17245)	-	3960860..3961264 (+)	405	WP_330331302.1	TIGR03618 family F420-dependent PPOX class oxidoreductase	-
OHS33_RS17255 (OHS33_17250)	-	3961476..3961799 (-)	324	WP_330331303.1	(2Fe-2S)-binding protein	-
OHS33_RS17260 (OHS33_17255)	-	3961796..3962092 (-)	297	WP_330331304.1	hypothetical protein	-
OHS33_RS17265 (OHS33_17260)	-	3962177..3963259 (+)	1083	WP_330331305.1	helix-turn-helix transcriptional regulator	-
OHS33_RS17270 (OHS33_17265)	-	3963382..3963834 (-)	453	WP_330331306.1	helix-turn-helix domain-containing protein	-
OHS33_RS17275 (OHS33_17270)	dnaJ	3963836..3965026 (-)	1191	WP_330331307.1	molecular chaperone DnaJ	-

Sequence

Protein

• Length: 861 a.a.
• Molecular weight: 93681.15 Da
• Isoelectric Point: 4.7097

>NTDB_id=646590 OHS33_RS17245 WP_330331301.1 3958131..3960716(-) (clpC) [Streptomyces sp. NBC_00536]
MDAELTNKSRAALNAATSRAVQAGHADLTPAHLLLALLTGEDNENVTDLLAATEADQAVVRAGAERLLAALPSVTGSTVA
PPQPSRDLLAVLAEADREAGRLGDEYLSTEHLLIAIAAKGGPAGEVLSAQGATADRLLTAFETSRGGRRVTSPDPEGQYK
ALEKFGTDFTAAAREGKLDPVIGRDQEIRRVVQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQRIVKGDVPESLKNKRLVS
LDLGAMVAGAKYRGEFEERLKTVLAEIKSSDGQIITFIDELHTVVGAGAGGDSAMDAGNMLKPMLARGELRMVGATTLDE
YRERIEKDPALERRFQQVLVAEPSVEDTIAILRGLKGRYEAHHKVVINDSALVAAATLSDRYITSRFLPDKAIDLVDESM
SRLRMEIDSSPLEIDELQRSVDRLRMEELALNHESDPASIERLDKLRKDLADKEEDLRGLNARWEKEKQSLNRVGELKER
LDDLRGQAERAQRDGDFDAASKLLYGEIPALERELAEATEAEAEVSLDTMVKDEVGPDDIADVVGAWTGIPAGRLLEGET
QKLLRMEEELGRRLIGQKEAVQAVSDAVRRTRAGIADPDRPTGSFLFLGPTGVGKTELAKALADFLFDDERAMIRIDMSE
YGEKHSVARLVGAPPGYVGYEEGGQLTEAVRRRPYSVVLLDEVEKAHPEVFDVLLQVLDDGRLTDGQGRTVDFRNTILVL
TSNLGSQHLMDPLTSAEVKKAQVLEVVRASFKPEFINRLDDLVVFSALDRDELAHIAELQIARLAARLAERRLTLDVTPE
ALAWLADKGNDPAYGARPLRRLIQTAVGDRLAREILAGEVKDGDTVRVDVAGDGLLVGKAL

Nucleotide

• Length: 2586 bp

>NTDB_id=646590 OHS33_RS17245 WP_330331301.1 3958131..3960716(-) (clpC) [Streptomyces sp. NBC_00536]
GTGGACGCCGAGCTGACCAACAAGAGCCGGGCCGCCCTGAACGCCGCCACCAGCAGGGCGGTCCAGGCCGGCCACGCCGA
CCTGACCCCCGCGCACCTGCTGCTGGCCCTGCTCACGGGCGAGGACAACGAGAACGTCACCGACCTGCTCGCCGCCACCG
AGGCCGACCAGGCCGTCGTACGGGCGGGCGCCGAGCGCCTGCTCGCCGCGCTGCCCAGCGTCACCGGATCCACGGTCGCG
CCGCCGCAGCCCAGCCGCGACCTGCTCGCCGTACTCGCCGAGGCCGACCGCGAGGCCGGACGGCTCGGCGACGAGTACCT
CTCCACCGAACACCTCCTCATCGCCATCGCCGCCAAGGGCGGCCCGGCGGGCGAGGTCCTTTCCGCACAAGGCGCGACCG
CCGACCGGCTGCTGACCGCTTTCGAGACCTCAAGAGGAGGGCGGCGGGTGACCTCCCCCGACCCCGAGGGCCAGTACAAG
GCCCTGGAGAAGTTCGGCACCGACTTCACGGCCGCGGCCCGCGAGGGCAAGCTCGACCCGGTGATCGGCCGGGATCAGGA
GATCCGGCGGGTGGTCCAGGTGCTGTCGCGCCGGACGAAGAACAACCCGGTGCTGATCGGCGAGCCCGGCGTCGGCAAGA
CGGCCGTGGTCGAGGGTCTGGCCCAGCGGATCGTGAAGGGCGATGTCCCCGAGTCCCTCAAGAACAAGCGGCTCGTCTCC
CTGGACCTCGGCGCGATGGTGGCCGGCGCCAAGTACCGCGGCGAATTCGAGGAACGGCTCAAGACCGTCCTCGCGGAGAT
CAAGTCCAGCGACGGGCAGATCATCACCTTCATCGACGAGCTGCACACCGTCGTCGGCGCGGGCGCCGGCGGGGACTCCG
CCATGGACGCGGGCAACATGCTCAAGCCCATGCTGGCCCGCGGCGAGCTGCGGATGGTCGGCGCGACCACGCTGGACGAG
TACCGCGAGCGGATCGAGAAGGACCCGGCCCTGGAGCGCCGCTTCCAGCAGGTGCTGGTCGCCGAGCCGAGCGTCGAGGA
CACCATCGCGATCCTGCGCGGGCTCAAGGGCCGCTACGAAGCCCACCACAAGGTGGTCATCAACGACAGCGCGCTCGTCG
CCGCGGCCACCCTGTCCGACCGGTACATCACCTCGCGGTTCCTCCCCGACAAGGCGATCGACCTGGTGGACGAGTCCATG
TCCCGGCTCCGCATGGAGATCGACTCCTCCCCGCTGGAGATCGACGAGCTGCAGCGCTCGGTCGACCGCCTCCGGATGGA
GGAGCTGGCCCTGAACCACGAGTCCGACCCGGCCTCGATCGAGCGCTTGGACAAGCTCCGCAAGGACCTCGCCGACAAGG
AGGAGGACCTGCGCGGCCTGAACGCCCGCTGGGAGAAGGAGAAGCAGTCCCTCAACCGGGTCGGCGAGCTGAAGGAACGC
CTCGACGACCTGCGCGGACAGGCCGAGCGCGCCCAGCGCGACGGCGATTTCGACGCGGCCTCGAAGCTGCTGTACGGGGA
GATCCCGGCGCTGGAGCGGGAGCTGGCGGAGGCCACCGAGGCCGAGGCGGAGGTCTCCCTCGACACCATGGTGAAGGACG
AGGTCGGTCCGGACGACATCGCCGACGTGGTGGGCGCCTGGACCGGCATCCCGGCCGGACGGCTCCTCGAAGGCGAGACG
CAGAAGCTGCTGCGCATGGAGGAGGAACTGGGCCGCCGTCTGATCGGGCAGAAGGAGGCGGTGCAGGCCGTCTCGGACGC
GGTGCGCCGCACCCGTGCGGGGATCGCGGACCCGGACCGGCCGACGGGCTCGTTCCTCTTCCTGGGCCCCACCGGTGTCG
GCAAGACCGAGCTGGCGAAGGCCCTCGCCGACTTCCTCTTCGACGACGAGCGGGCCATGATCCGCATCGACATGTCGGAG
TACGGCGAGAAGCACAGCGTGGCCCGGCTCGTCGGCGCCCCGCCCGGATACGTCGGCTACGAGGAGGGCGGCCAGCTCAC
CGAGGCGGTGCGCAGGCGCCCGTACTCGGTGGTCCTCCTCGACGAGGTGGAGAAGGCCCACCCGGAGGTCTTCGACGTGC
TGCTCCAGGTCCTGGACGACGGGCGTCTCACGGACGGGCAGGGCCGGACCGTGGACTTCCGCAACACCATCCTGGTGCTG
ACCTCGAATCTGGGCAGCCAGCACCTGATGGACCCGCTGACCTCGGCGGAGGTGAAGAAGGCGCAGGTCCTGGAGGTGGT
CCGGGCGAGCTTCAAGCCGGAGTTCATCAACCGGCTCGACGACCTCGTGGTGTTCTCGGCCCTCGACCGGGACGAGCTGG
CGCACATCGCCGAACTCCAGATCGCCCGCCTCGCGGCCCGTCTCGCGGAGCGGCGGCTGACCCTGGACGTGACCCCCGAG
GCGCTGGCCTGGCTCGCCGACAAGGGCAACGACCCGGCGTACGGAGCGCGGCCGCTGCGCCGCCTGATCCAGACCGCGGT
CGGCGACCGGCTGGCCCGCGAGATCCTGGCGGGCGAGGTCAAGGACGGCGACACCGTCCGCGTGGACGTGGCGGGCGACG
GCCTGCTCGTCGGCAAGGCGCTGTGA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (768-848)

• ATPase family associated with various cellular activities (AAA) (AAA) (204-338)

• AAA lid domain (AAA_lid_9) (344-446)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (18-42)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-146)

• AAA domain (Cdc48 subfamily) (AAA_2) (600-761)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	45.516	100	0.466
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.008	100	0.416
clpC	Lactococcus lactis subsp. cremoris KW2	44.875	83.856	0.376